Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Structure
(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester structure
CAS No.
1168150-46-6
Chemical Name:
(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester
Synonyms
(3E)-2;Nintedanib-017;BIBF1120 Intermediate4;Nintedanib impurities3;Nintedanib Impurity 125;Nintedanib Intermediate 4;Nintedanib ethanesulfonate intermediates;oxo-1h-indole-6-carboxylic acid methyl ester;3E-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-...;methyl (E)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
CBNumber:
CB92671010
Molecular Formula:
C18H15NO4
Molecular Weight:
309.32
MDL Number:
MFCD28139165
MOL File:
1168150-46-6.mol
Last updated:2023-12-19 16:21:16
Request For Quotation

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Properties

Boiling point 523.8±50.0 °C(Predicted)
Density 1.273±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka 10.62±0.20(Predicted)
form Solid
color Light Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M322025 (E)-Methyl3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 1168150-46-6 100mg $110 2021-12-16 Buy
TRC M322025 (E)-Methyl3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 1168150-46-6 250mg $225 2021-12-16 Buy
TRC M322025 (E)-Methyl3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 1168150-46-6 500mg $425 2021-12-16 Buy
TRC M322025 (E)-Methyl3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 1168150-46-6 1g $795 2021-12-16 Buy
AK Scientific 0001AP Methyl(3E)-3-[methoxy(phenyl)methylene]-2-oxo-6-indolinecarboxylate 1168150-46-6 25mg $39 2021-12-16 Buy
Product number Packaging Price Buy
M322025 100mg $110 Buy
M322025 250mg $225 Buy
M322025 500mg $425 Buy
M322025 1g $795 Buy
0001AP 25mg $39 Buy

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Chemical Properties,Uses,Production

Uses

(E)-Methyl 3-(Methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is an intermediate of (E)-Intedanib [I666670]. It is also used as a reactant in the preparation of deuterated derivatives of Nintedanib (N478290), which is angiokinase inhibitor with antitumor activity.

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester synthesis

1174335-83-1
1168150-46-6
Synthesis of (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester from Nintedanib

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Suppliers

Global( 139)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15371 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1811 55
Shanghai Yingrui Biopharma Co., Ltd. 		+86-21-33585366 - 03@ sales03@shyrchem.com CHINA 738 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Hangzhou Cyanochem Co., Ltd. 		+86 17788583750 sales@cyanochem.com CHINA 283 58
Jinan Finer Chemical Co., Ltd 		+86-531-88989536 +86-15508631887 sales@finerchem.com China 2966 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Shanghai Yingrui Biopharma Co.,Ltd 		21-33585366 export01@shyrchem.com CHINA 1320 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
Shanghai Yingrui Biopharma Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Hangzhou Cyanochem Co., Ltd. 		58
Jinan Finer Chemical Co., Ltd 		58
Chongqing Chemdad Co., Ltd 		58
Shanghai Yingrui Biopharma Co.,Ltd 		58

View Lastest Price from (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(E)-methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate pictures 2023-12-19 (E)-methyl 3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
1168150-46-6
 US $0.00-0.00 / kg 1kg 98% 1 ton Nanjing Fred Technology Co., Ltd
(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester pictures 2022-10-01 (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester
1168150-46-6
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
methyl (E)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate pictures 2022-02-25 methyl (E)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
1168150-46-6
 US $100.00 / Kg/Bag 1Kg/Bag 98% 10KG Hong Kong Tiansheng New Material Trading Co., Ltd

1168150-46-6((3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester)Related Search:

Methyl 2-oxoindole-6-carboxylate 1-Chloro-4-(trimethoxymethyl)benzene Methyl 1-acetyl-2-oxoindoline-6-carboxylate N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide N-methyl-N-(4-nitrophenyl)-2-(piperazin-1-yl)acetamide
BIBF 1202 (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Avibactam sodium Nintedanib 1-(2-chloroacetyl)-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester
Avibactam INT 1 BIBF-1120 2-CHLORO-N-METHYL-N-(4-NITROPHENYL)ACETAMIDE 2-broMo-N-Methyl-N-(4-nitrophenyl)acetaMide N-(4-aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide
N-methyl-2-(4-methylpiperazin-1-yl)-N-(4-nitrophenyl)acetamide 1,3-DiMethyl 2-[4-(Methoxycarbonyl)-2-nitrophenyl]propanedioate Nintedanib Ethanesulfonate Salt

1of4

(3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester BIBF1120 Intermediate4 Nintedanib ethanesulfonate intermediates (3E)-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl este methyl (E)-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate 1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(methoxyphenylmethylene)-2-oxo-, methyl ester, (3E)- Nintedanib Intermediate 4 (3E)-2 3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-carboxylic acid methyl ester Nintedanib-017 oxo-1h-indole-6-carboxylic acid methyl ester Nintedanib Impurity 125 3E-2,3-Dihydro-3-(methoxyphenylmethylene)-2-oxo-1H-indole-6-... Nintedanib impurities3 1168150-46-6