Elamipretide
- CAS No.
- 736992-21-5
- Chemical Name:
- Elamipretide
- Synonyms
- MTP-131;Centanafadine;SS-31, Elamipretide;Elamipretide acetate;RX-31;SS-31);Bendavia);Elamipretide;ELAMIPRETIDE, >99%;Elamipretide (SS-31
- CBNumber:
- CB92708860
- Molecular Formula:
- C32H49N9O5
- Molecular Weight:
- 639.79
- MDL Number:
- MFCD20133791
- MOL File:
- 736992-21-5.mol
Density | 1.34±0.1 g/cm3(Predicted) |
---|---|
solubility | Methanol (Slightly), Water (Slightly) |
pka | 10.10±0.25(Predicted) |
form | Solid |
color | White to Off-White |
Sequence | H-d-Arg-dimethylTyr-Lys-Phe-NH2 |
Stability | Hygroscopic |
InChIKey | SFVLTCAESLKEHH-WKAQUBQDSA-N |
SMILES | C(N)(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC1=C(C)C=C(O)C=C1C)NC(=O)[C@@H](CCCNC(N)=N)N |
FDA UNII | 87GWG91S09 |
Elamipretide Chemical Properties,Uses,Production
Description
Elamipretide, also known as MTP 131, is a mitochondria-targeted peptide antioxidant. Elamipretide decreases inflammation and protect against a variety of neurological illnesses. Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice. Elamipretide Promotes Mitophagosome Formation and Prevents Its Reduction Induced by Nutrient Excess in INS1 β-cells.
Uses
D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide-d5 Trifluoroacetic Acid Salt is labelled D-Arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl-L-phenylalaninamide (A769700) which is a mitochondrial-targeted compound that re-energizes ischemic mitochondria by interacting with cardiolipin. It is a cell-permeable antioxidant peptide.
Mechanism of action
Elamipretide can inhibit the production of pathogenic ROS (reactive oxygen species) and restore mitochondrial ATP synthesis. Currently, the most accepted mechanism for these two actions is the direct interaction between Elamipretide and cardiolipin.
Side effects
Side effects of elamipretide include:
Mild redness or itching at the injection site
Headache
Dizziness
Elamipretide Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shandong Huisheng Import & Export Co., Ltd. | +86-13176845580 +86-13176845580 | da@zhongda-biotech.com | China | 248 | 58 |
ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD | +8619155187336 | shengzhikai3@shengzhikai.com | China | 38 | 58 |
Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
Shanghai Chinqesen Biotechnology Co., Ltd. | +86-16628886292 +86-19521323435 | sales2@qschem-pharma.com | China | 46 | 58 |
Hebei Yime New Material Technology Co., Ltd. | +86-66697723 +86-17703311139 | admin@china-yime.com | China | 563 | 58 |
Shanghai Yunao International Trade Co., Ltd | +8617621705551 | asdf@shanghaihg.cn | China | 265 | 58 |
Henan Tengmao Chemical Technology Co. LTD | +8615238638457 | salesvip2@hntmhg.com | China | 415 | 58 |
qingdao future trading Co., Ltd | +86-13335044410 +86-13335044410 | cui56813@163.com | China | 110 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
Anhui Zhongda Biotechnology Co., Ltd | +8619956560829 | justine@zhongda-biotech.com | China | 300 | 58 |
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View Lastest Price from Elamipretide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-04-25 | SS-31
736992-21-5
|
US $150.00-100.00 / box | 2box | 99% | 100000kg | Hebei Kangcang new material Technology Co., LTD | ||
2024-04-25 | SS-31,Elamipretide
736992-21-5
|
US $0.00 / G | 1G | 99% | 20 | CONTIDE BIOTECH CO.,LTD | ||
2024-04-25 | Elamipretide
736992-21-5
|
US $9.90-9.90 / g | 1g | 99% | 1000g | Wuhan Cell Pharmaceutical Co., Ltd |
- SS-31
736992-21-5
- US $150.00-100.00 / box
- 99%
- Hebei Kangcang new material Technology Co., LTD
- SS-31,Elamipretide
736992-21-5
- US $0.00 / G
- 99%
- CONTIDE BIOTECH CO.,LTD
- Elamipretide
736992-21-5
- US $9.90-9.90 / g
- 99%
- Wuhan Cell Pharmaceutical Co., Ltd