ChemicalBook >> CAS DataBase List >>ACK1-B19
ACK1-B19
- CAS No.
- 1234480-46-6
- Chemical Name:
- ACK1-B19
- Synonyms
- CS-2588;XMD8-87;ACK1-B19;XMD8-87 (ACK1-B19);XMD-8-87;XMD8 87;XMD 8 87;Tyrosinase,Inhibitor,inhibit,XMD8 87,XMD-8-87,XMD887,XMD8-87;2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one;2-[[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one;5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one;6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-
- CBNumber:
- CB92716117
- Molecular Formula:
- C24H27N7O2
- Molecular Weight:
- 445.52
- MDL Number:
- MFCD30742941
- MOL File:
- 1234480-46-6.mol
Last updated:2024-07-02 08:55:41
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
ACK1-B19 price More Price(18)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 23354 | XMD8-87 ≥98% | 1234480-46-6 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 23354 | XMD8-87 ≥98% | 1234480-46-6 | 5 mg | $95 | 2024-03-01 | Buy |
Cayman Chemical | 23354 | XMD8-87 ≥98% | 1234480-46-6 | 10mg | $191 | 2023-01-06 | Buy |
Tocris | 6061 | XMD8-87 ≥98%(HPLC) | 1234480-46-6 | 10 | $183 | 2021-12-16 | Buy |
Tocris | 6061 | XMD8-87 ≥98%(HPLC) | 1234480-46-6 | 50 | $771 | 2021-12-16 | Buy |
ACK1-B19 Chemical Properties,Uses,Production
Description
XMD8-87 is an inhibitor of tyrosine kinase non-receptor 2 (TNK2) with an IC50 value of 1.9 μM in HEK293T cells expressing human TNK2. It is selective for TNK2 over a panel of approximately 100 kinases with >90 and <50% inhibition for TNK2 and all other kinases tested, respectively. XMD8-87 inhibits growth of Ba/F3 cells expressing constitutively active mutant TNK2s (IC50s = 0.1-77 nM) commonly found in leukemias but has no effect on cells expressing wild-type TNK2 (IC50 = >1 μM).
Uses
XMD8-87 is used in the studies of benzopyrimidodiazepinones as most selective and potent ERK5 inhibitor.
ACK1-B19 Preparation Products And Raw materials
Raw materials
Preparation Products
ACK1-B19 Suppliers
Global( 59)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29822 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
1234480-46-6(ACK1-B19)Related Search:
ACK1-B19
XMD8-87
CS-2588
XMD-8-87;XMD8 87;XMD 8 87
2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one
5,11-Dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-
XMD8-87 (ACK1-B19)
2-((2-Methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-11-methyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one
Tyrosinase,Inhibitor,inhibit,XMD8 87,XMD-8-87,XMD887,XMD8-87
2-[[2-Methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one
1234480-46-6