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FMoc-Val-Cit-PAB-PNP

FMoc-Val-Cit-PAB-PNP structure

CAS No.: 863971-53-3

Chemical Name:: FMoc-Val-Cit-PAB-PNP

Synonyms: 4-[[(2S)-1-amino-5-(carbamoylamino)-1-oxopentan-2-yl]-[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate;(9H-fluoren-9-yl)methyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-1-oxobutan-2-yl)carbamate;Moc-Val-Cit-PAB-PNP;Fmoc-Val-Cit-PAB-PN;FMoc-Val-Cit-PAB-PNP;Fmoc-Val-Cit-PABC-PNP;Fmoc-Val-Cit-PAB-PNP-OH;Fmoc-Val-Cit-PAB-PNP, >95%;863971-53-3 FMoc-Val-Cit-PAB-PNP 1g;FMOC-VAL-CIT-PAB-PNP (9-FLUORENYLMETHYLOXYCARBONYL-VALYL-CITRULLYL-(4-AMINOBENZYL)-(4-NITROPHENYL)CARBONATE)

CBNumber:: CB92730904

Molecular Formula:: C40H42N6O10

Molecular Weight:: 766.8

MDL Number:: MFCD22200278

MOL File:: 863971-53-3.mol

Last updated:2024-03-29 16:09:00

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FMoc-Val-Cit-PAB-PNP Properties

Melting point	189 °C(dec.)
Boiling point	1024.0±65.0 °C(Predicted)
Density	1.335±0.06 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
form	powder to crystal
pka	10.63±0.46(Predicted)
color	White to Light yellow
Sequence	Fmoc-Val-Cit-PAB-PNP

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H227-H302+H312+H332
Precautionary statements	P280
HS Code	2924.29.7790

FMoc-Val-Cit-PAB-PNP price More Price(25)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	F1114	Fmoc-Val-Cit-PAB-PNP	863971-53-3	100MG	$161	2024-03-01	Buy
TCI Chemical	F1114	Fmoc-Val-Cit-PAB-PNP	863971-53-3	500MG	$640	2024-03-01	Buy
BroadPharm	BP-22309	Fmoc-Val-Cit-PAB-PNP 95%	863971-53-3	500mg	$750	2021-12-16	Buy
BroadPharm	BP-22309	Fmoc-Val-Cit-PAB-PNP 95%	863971-53-3	100mg	$255	2021-12-16	Buy
Iris Biotech GmbH	ADC1000	Fmoc-Val-Cit-PAB-PNP	863971-53-3	250mg	$337.5	2021-12-16	Buy

Product number	Packaging	Price	Buy
F1114	100MG	$161	Buy
F1114	500MG	$640	Buy
BP-22309	500mg	$750	Buy
BP-22309	100mg	$255	Buy
ADC1000	250mg	$337.5	Buy

FMoc-Val-Cit-PAB-PNP Chemical Properties,Uses,Production

Description

Fmoc-Val-Cit-PAB-PNP is a a cleavable ADC linker used in antibody drug conjugate. The Val-Cit linker was designed to be cleaved by cathepsin B. PNP group is a good leaving group when reacting with amine bearing payload.

Biological Activity

Fmoc-Val-Cit-PAB-PNP is a cleavable ADC linker that can be used to synthesize antibody drug conjugates (ADCs).

FMoc-Val-Cit-PAB-PNP synthesis

Synthesis of FMoc-Val-Cit-PAB-PNP from BIS(4-NITROPHENYL) CARBONATE and FMoc-Val-Cit-PAB

FMoc-Val-Cit-PAB-PNP Preparation Products And Raw materials

Raw materials

BIS(4-NITROPHENYL) CARBONATE 4-Aminobenzyl alcohol 4-Nitrophenyl chloroformate FMOC-L-Valine L-Citrulline

Fmoc-Val-Cit-OH FMOC-VAL-OSU FMoc-Val-Cit-PAB Methanol

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Preparation Products

FMoc-Val-Cit-PAB-PNP Suppliers

Global( 201)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	6992	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Jurong Coupling Biotechnology Co., Ltd.	13656108824	coupling278191416@hotmail.com	CHINA	184	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
GL Biochem (Shanghai) Ltd.	+86-021-61263370 +86-18901917034		CHINA	3904	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9702	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Shenzhen Nexconn Pharmatechs Ltd	58
Jinan Carbotang Biotech Co.,Ltd.	58
BOC Sciences	58
Jurong Coupling Biotechnology Co., Ltd.	58
career henan chemical co	58
GL Biochem (Shanghai) Ltd.	58
AFINE CHEMICALS LIMITED	58
Finetech Industry Limited	58

View Lastest Price from FMoc-Val-Cit-PAB-PNP manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-03-29	Fmoc-Val-Cit-PAB-PNP 863971-53-3	US $0.00 / g	5g	>95.00%	5g	Xian confluore Biological Technology Co., Ltd.
2020-02-19	FMoc-Val-Cit-PAB-PNP 863971-53-3	US $7.00 / KG	1KG	99%	100kg	Career Henan Chemical Co
2020-02-19	FMoc-Val-Cit-PAB-PNP 863971-53-3	US $7.00 / KG	1KG	99%	100kg	Career Henan Chemical Co

Fmoc-Val-Cit-PAB-PNP
863971-53-3
US $0.00 / g
>95.00%
Xian confluore Biological Technology Co., Ltd.

FMoc-Val-Cit-PAB-PNP
863971-53-3
US $7.00 / KG
99%
Career Henan Chemical Co

FMoc-Val-Cit-PAB-PNP
863971-53-3
US $7.00 / KG
99%
Career Henan Chemical Co

863971-53-3(FMoc-Val-Cit-PAB-PNP)Related Search:

Fmoc-PEG5-NHS ester Fmoc-N-amido-PEG1-acid Fmoc-NH-PEG6-CH2COOH FMOC-12-AMINO-4,7,10-TRIOXADODECANOIC ACID FMOC-21-AMINO-4,7,10,13,16,19-HEXAOXAHENEICOSANOIC ACID

Fmoc-PEG4-NHS ester Val-cit-PAB-OH pyrene-2,7-diyldiboronic acid Fmoc-Val-Cit-OH FMoc-Val-Cit-PAB

MC-Val-Cit-PAB

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FMoc-Val-Cit-PAB-PNP {4-[(2S)-5-(carbamoylamino)-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]pentanamido]phenyl}methyl 4-nitrophenyl carbonate Moc-Val-Cit-PAB-PNP Fmoc-Val-Cit-PAB-PNP, >95% L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]- FMOC-VAL-CIT-PAB-PNP (9-FLUORENYLMETHYLOXYCARBONYL-VALYL-CITRULLYL-(4-AMINOBENZYL)-(4-NITROPHENYL)CARBONATE) 4-[[(2S)-1-amino-5-(carbamoylamino)-1-oxopentan-2-yl]-[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate (9H-fluoren-9-yl)methyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-1-oxobutan-2-yl)carbamate 863971-53-3 FMoc-Val-Cit-PAB-PNP 1g Fmoc-Val-Cit-PABC-PNP Fmoc-Val-Cit-PAB-PNP-OH Fmoc-Val-Cit-PAB-PN 863971-53-3 63971-53-3 C40H42N6O10 Pharmaceutical ADCs ADC-Linker ADC-Linkers