Brilacidin
- CAS No.
- 1224095-98-0
- Chemical Name:
- Brilacidin
- Synonyms
- PMX 30063;Stroquinan;Brilacidin;4,6-Pyrimidinedicarboxamide, N4,N6-bis[3-[[5-[(aminoiminomethyl)amino]-1-oxopentyl]amino]-2-[(3R)-3-pyrrolidinyloxy]-5-(trifluoromethyl)phenyl]-
- CBNumber:
- CB92741737
- Molecular Formula:
- C40H50F6N14O6
- Molecular Weight:
- 936.91
- MDL Number:
- MFCD23726663
- MOL File:
- 1224095-98-0.mol
- MSDS File:
- SDS
Density | 1.57±0.1 g/cm3(Predicted) |
---|---|
storage temp. | Store at -20°C |
solubility | Soluble in DMSO |
pka | 9.47±0.70(Predicted) |
FDA UNII | I1679X069H |
Brilacidin Chemical Properties,Uses,Production
Enzyme inhibitor
This membrane-lyzing defensin mimetic (FW = 932.98 g/mol; CAS 1224095-98-0; IUPAC: N,N’-bis[3-{[5-(carbamimidoylamino)pentanoyl] amino}-2-[(3R)-pyrrolidin-3-yloxy]-5-(trifluoromethyl)phenyl]pyrimidine- 4,6-dicarboxamide)) is bactericidal (not simply bacteriostatic like most antibiotic) toward a broad spectrum of bacteria, but not mammalian cells. Brilacidin kills many Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus faecium as well as Gramnegative bacteria, including Eschericia coli and Klebsiella pneumonia (NDM). This action of this drug commend it for use in controlling Acute Bacterial Skin and Skin Structure Infections (ABSSSI). A five-day treatment course is usually effective in the treatment of many infections, and, given its direct membrane-disrupting action, bacteria are highly unlikely to acquire resistance to brilacidin.
Brilacidin Preparation Products And Raw materials
Raw materials
Preparation Products
Brilacidin Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
Shanghai Changyan Chem & Tech Co., Ltd. | 021-021-20242659 18930833303 | order@changyanchem.com | China | 5008 | 55 |
Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | eric@peptidego.com | China | 6347 | 58 |
Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
Zhejiang Huida Biotech Co., LTD | 0571-89903882 13626641628 | jiangnan@huidabiotech.com | China | 3661 | 58 |
View Lastest Price from Brilacidin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-05-17 | Brilacidin
1224095-98-0
|
US $0.00 / g | 1g | 98% | 1kg | BOC Sciences |
- Brilacidin
1224095-98-0
- US $0.00 / g
- 98%
- BOC Sciences