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Sodium propionate

description Chemical properties Uses health risks Toxicity Usage limit
Sodium propionate
Sodium propionate structure
Chemical Name:
Sodium propionate
Molecular Formula:
Formula Weight:
MOL File:

Sodium propionate Properties

Melting point:
285-286 °C (lit.)
storage temp. 
Inert atmosphere,Room Temperature
H2O: 0.1 g/mL, clear
Crystalline Powder
8-9.5 (10g/l, H2O, 20℃)
Water Solubility 
995 g/L (20 ºC)
Stable. Incompatible with strong oxidizing agents. Hygroscopic.
CAS DataBase Reference
137-40-6(CAS DataBase Reference)
184.1784; 582.3784; 181.23; 310.545; 573.940
Substances Added to Food (formerly EAFUS)
SCOGS (Select Committee on GRAS Substances)
Sodium propionate
EWG's Food Scores
NCI Drug Dictionary
sodium propionate
ATC code
NIST Chemistry Reference
Sodium propanoate(137-40-6)
EPA Substance Registry System
Sodium propionate (137-40-6)
  • Risk and Safety Statements
Signal word  Warning
Hazard statements  H312
Precautionary statements  P280h-P302+P352a-P312a-P321-P362+P364-P501a-P280
Hazard Codes  Xn
Risk Statements  21-38-36/37/38
Safety Statements  36/37-36/37/39-26-36
WGK Germany  1
RTECS  UF7525000
HS Code  29159000

Sodium propionate price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W518905 Sodium propionate FCC 137-40-6 1 SAMPLE-K $50 2021-12-16 Buy
Sigma-Aldrich 18108 Sodium propionate meets analytical specification of NF, 99-100.5% (ex dried subst.) 137-40-6 1kg $61.8 2021-12-16 Buy
Sigma-Aldrich 49894 Sodium propionate certified reference material, TraceCERT 137-40-6 100mg $100 2021-12-16 Buy
Sigma-Aldrich W518905 Sodium propionate FCC 137-40-6 10 kg $224 2021-12-16 Buy
Sigma-Aldrich W518905 Sodium propionate FCC 137-40-6 25 kg $352 2021-12-16 Buy

Sodium propionate Chemical Properties,Uses,Production


Sodium propionate is the salt form of propionic acid, which is an organic acid that is produced during the chemical degradation of sugar. It is a compound that is produced naturally in the body when certain fatty acids and amino acids are metabolized. Propionic acid is metabolized by a series of enzymatic reactions that are dependent on the presence of vitamin B-12, according to a 1996 article in the "International Journal of Vitamin and Nutrition Research." Sodium propionate is also chemically manufactured for a variety of industrial uses.
Sodium propionate is a common food additive that is industrially manufactured but also occurs in nature. Since it is toxic to mold and some species of bacteria, it is an especially effective additive in baked goods or other products that are susceptible to spoilage.
sodium propionate is an effective inhibitor of the growth of certain molds and some bacteria in bakery goods. It is usually preferred in non-yeast leavened bakery products because the calcium ions’ of calcium propionate interfere with the chemical leavening agents. In those bakery products, such as cakes, tortillas, pie fillings etc., chemically leaved agents are used (e.g. baking powder). sodium propionate  is easy to handle and easy to incorporate into flour.
It is a safe compound when encountered at the low levels found in food.

Chemical properties

It appears as transparent particles or crystal with specific smelly odor. It is easily subject to deliquescence in wet air. It is soluble in water, slightly soluble in alcohol.


Primary uses: Antifungal agent, antiseptic agent (topical), disinfectant, food additive, ophthalmic agent.
It is used primarily as a mold inhibitor in bakery products. It is approved for use as a food additive in the EU, USA and Australia and New Zealand (where it is listed by its INS number 281). Chemically synthesized sodium propionate is most commonly used as a preservative in the food industry. It prevents the growth of mold and some bacteria, thereby prolonging the shelf life of packaged baked goods. According to the Code of Federal Regulations, sodium propionate is generally recognized as safe when used as a food additive. It is also used to prevent mold growth in packaged and processed cheese products. In addition, ammonium propionate is used as an additive in animal feed to prevent overgrowth of unwanted bacteria in the stomachs of livestock.
  1. It can be used as preservatives; used for anti-mould for cakes, waxberry and other mildew
  2. It can be used as germicide and antiseptic.
  3. Sodium propionate wet acid preservative has its antibacterial effect be affected by the environmental PH. The minimum inhibitory concentration was 0.01% at pH 5.0 and 0.5% at pH 6.5. In acidic medium, it has a strong inhibitory effect against various types of mold, aerobic bacillus or Gram-negative bacteria. It has special effect in prevention the production of aflatoxin while having no effect on the yeast. In addition, it is also used as a food preservative.
  4. In the leather, it can be used as masking agent in order to improve the alkali resistance of leather and tanning uniformity.
  5. In the food industry, it can be used for pastry preservation with the usage amount of 2.5g/kg (based on propionic acid, the same as below); in 3% to 5% aqueous solution, the maximal amount for soaking waxberry is 50g/kg. It can also be used as feed antiseptic.
  6. Germicide, antiseptic. Used for determination of transaminase; The general dosage is 0.1-0.3%.

health risks

Sodium propionate and calcium propionate are good preservatives, especially in food because very low toxicity has great advantages, bread usually calcium propionate, because bread is yeast fermentation, the use of sodium propionate can So that d increases dough, affecting yeast growth, will extend the time to face.
According to the Material Safety Data Sheet for sodium proprionate, as reported on, the pure chemical can irritate the skin if handled. However, since the general public would not come in contact with sodium propionate in its pure form, it does not likely present a risk. The risks of consuming sodium propionate are slight if you compare it to the possibility of consuming products that have mold or bacterial contamination. If you are worried about consuming sodium propionate, buy fresh bread or bake your own.


ADI has not been subject to any specific restriction (FAO/WHO, 2001).
LD50 5.1 g/kg (mouse, oral).
GRAS (FDA, § 184.1784, 2000).

Usage limit

GB 2760-96 (g/kg): pastry 2.5; soaking waxberry: 30 to 50; impregnated with 3% to 5% aqueous solution; should be washed before processing, calculated on propionic acid.
FAO/WHO (1984): processed cheese 3000mg/kg.
EEC regulations: it can be used for dairy products, bakery products, cheese and so on. Still used as beer and other viscous substances inhibitor.


Sodium propanoate or sodium propionate is the sodium salt of propionic acid which has the chemical formula Na(C2H5COO).

Chemical Properties

Colourless crystals or, white or almost white powder, slightly hygroscopic.


Fungicide, mold preventative.


It is used as a food preservative and is represented by the food labeling E number E281 in Europe; it is used primarily as a mold inhibitor in bakery products. It is approved for use as a food additive in the EU, USA and Australia and New Zealand ( where it is listed by its INS number 281 ) .


Sodium Propionate is an antimicrobial agent that is the sodium salt of propionic acid. it occurs as colorless, transparent crystals or a gran- ular crystalline powder. it is odorless or has a faint acetic–butyric acid odor, and is deliquescent. it is prepared by neutralizing propionic acid with sodium hydroxide. it is used in baked goods; nonalcoholic beverages; cheeses; confections and frostings; gelatins, puddings, and fillings; jams and jellies; meat products; and soft candy.


ChEBI: An organic sodium salt comprising equal numbers of sodium and propionate ions.


It is produced by the reaction of propionic acid and sodium carbonate or sodium hydroxide.

General Description

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at:

Safety Profile

Moderately toxic by skin contact and subcutaneous routes. Mildly toxic by unspecified routes. An allergen. When heated to decomposition it emits toxic fumes of Na2O.

Purification Methods

Recrystallise it from H2O (solubility 10%) and dry by heating at 100o for 4hours. The solubility of the anhydrous salt in MeOH is 13% at 15o and 13.77% at 68o. It is insoluble in *C6H6 and Me2CO. [Henstock J Chem Soc 1341 1934, Beilstein 2 IV 701.]

Sodium propionate Preparation Products And Raw materials

Raw materials

Preparation Products

Sodium propionate Suppliers

Global( 336)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
02569916489 CHINA 259 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 China 22607 55
Hangzhou FandaChem Co.,Ltd.
+86-571-56059825 CHINA 9128 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418697 China 3000 55
Shanxi Naipu Import and Export Co.,Ltd
+8613734021967 CHINA 1011 58
career henan chemical co
+86-0371-55982848 China 29954 58
Hubei Jusheng Technology Co.,Ltd.
027-59599243 CHINA 28229 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282 China 5942 58
hdzhl biotechnology co., ltd
86-13032617415 CHINA 1275 58
Chongqing Chemdad Co., Ltd
+86-13650506873 CHINA 37282 58

View Lastest Price from Sodium propionate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2022-01-20 New product CAS 137-40-6 food additive sodium propionate for sale
US $1.00 / KG 1KG 99% 20tons Shanxi Naipu Import and Export Co.,Ltd
2022-01-20 best price food grade sodium propionate
US $1.00 / KG 1KG 99% 20ton Shanxi Naipu Import and Export Co.,Ltd
2022-01-06 Sodium Propionate
US $88.00 / KG 1KG Above97% Weekly supply of 1000KG Wuhan Dujiang Industrial Co., Ltd.

Sodium propionate Spectrum

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