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2-PHENYLPROPIONIC ACID

CAS No.
492-37-5
Chemical Name:
2-PHENYLPROPIONIC ACID
Synonyms
HYDRATROPIC ACID;Benzeneacetic acid, .alpha.-methyl-;2-Phenylproplonic Acid;(±)-α-methylphenylaceticacid;(±)-2-Phenylpropionic acid, (±)-Hydratropic acid;dl-PPA;2-Phenylpropionic;RARECHEM AL BO 0089;TIMTEC-BB SBB007855;DL-HYDRATROPIC ACID
CBNumber:
CB9293539
Molecular Formula:
C9H10O2
Molecular Weight:
150.18
MDL Number:
MFCD00002650
MOL File:
492-37-5.mol
MSDS File:
SDS
Last updated:2024-04-16 14:59:45

2-PHENYLPROPIONIC ACID Properties

Melting point 5 °C
Boiling point 260-262 °C (lit.)
Density 1.1 g/mL at 25 °C (lit.)
refractive index n20/D 1.522(lit.)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
solubility 9.9g/l
form Liquid
pka 4.34±0.10(Predicted)
color Clear pale yellow to yellow
PH 3 (5g/l, H2O, 20℃)
Water Solubility 10 g/L (20 ºC)
BRN 1863558
LogP 1.699 (est)
CAS DataBase Reference 492-37-5(CAS DataBase Reference)
FDA UNII CH15E393A2
NIST Chemistry Reference Benzeneacetic acid, «alpha»-methyl-(492-37-5)
EPA Substance Registry System Benzeneacetic acid, .alpha.-methyl- (492-37-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P280-P303+P361+P353-P305+P351+P338+P310
Hazard Codes  Xi,C
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
TSCA  Yes
HS Code  29163900
NFPA 704
1
1 0

2-PHENYLPROPIONIC ACID price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P31701 2-Phenylpropionic acid 97% 492-37-5 5g $41.4 2024-03-01 Buy
Sigma-Aldrich P31701 2-Phenylpropionic acid 97% 492-37-5 10g $80.3 2024-03-01 Buy
TCI Chemical P0699 DL-2-Phenylpropionic Acid >98.0%(GC)(T) 492-37-5 5g $16 2024-03-01 Buy
TCI Chemical P0699 DL-2-Phenylpropionic Acid >98.0%(GC)(T) 492-37-5 25g $44 2024-03-01 Buy
Alfa Aesar L00709 (±)-2-Phenylpropionic acid, 98% 492-37-5 5g $33.65 2024-03-01 Buy
Product number Packaging Price Buy
P31701 5g $41.4 Buy
P31701 10g $80.3 Buy
P0699 5g $16 Buy
P0699 25g $44 Buy
L00709 5g $33.65 Buy

2-PHENYLPROPIONIC ACID Chemical Properties,Uses,Production

Chemical Properties

clear pale yellow to yellow liquid

Uses

2-Phenylpropionic acid is used in the preparation of ibuprofen derivatives for their anti-inflammatory activity. Also used in nucleation inhibitors in Dutch resolution of diastereomers.

Definition

ChEBI: A 2-arylpropionic acid carrying a phenyl group at position 2. It is a metabolite of alpha-methylstyrene (AMS), a volatile hydrocarbon.

Synthesis Reference(s)

Journal of the American Chemical Society, 99, p. 182, 1977 DOI: 10.1021/ja00443a033
The Journal of Organic Chemistry, 51, p. 4354, 1986 DOI: 10.1021/jo00373a005
Tetrahedron Letters, 21, p. 581, 1980 DOI: 10.1016/S0040-4039(01)85562-3

Purification Methods

Fractionally distil the acid, or recrystallise it from pet ether (b 40-60o) with strong cooling (see references below). [Beilstein 9 II 348.]

2-PHENYLPROPIONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 392)Suppliers
Supplier Tel Email Country ProdList Advantage
Zhengzhou Anbu Chem Co.,Ltd
+86-0371-88006763; +8615988602810 sales@anbuchem.com China 3000 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 7786 58
airuikechemical co., ltd.
+undefined86-15315557071 sales02@airuikechemical.com China 994 58
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106 sales@frappschem.com China 885 50
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Jiangsu Qingquan Chemical Co., Ltd.
+86-571-86589381,86589382,86589383 sales1@qqpharm.com CHINA 154 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58

View Lastest Price from 2-PHENYLPROPIONIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	2-PHENYLPROPIONIC ACID pictures 2024-04-16 2-PHENYLPROPIONIC ACID
492-37-5
US $5.00-0.10 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
DL-2-Phenylpropionic acid pictures 2024-04-07 DL-2-Phenylpropionic acid
492-37-5
US $0.00-0.00 / g 1g 99.99% 20 tons airuikechemical co., ltd.
2-PHENYLPROPIONIC ACID pictures 2023-07-12 2-PHENYLPROPIONIC ACID
492-37-5
US $0.00 / KG 1KG 98% 1000KGS Zhengzhou Anbu Chem Co.,Ltd
(n)-2-phenylpropionic acid (n)-à-methylphenylacetic acid 2-HENYLPROPIONIC ACID 2-PHENYLPROPINICACID dl-PPA α-methyl-α-toluic acid 2-PHENYLPROPIONIC ACID 98% DL-α-phenylpropionic acid a-Methylbenzeneacetic acid rac-(2R*)-2-Phenylpropionic acid rac-(R*)-2-Phenylpropanoic acid DL-2-Phenylpropionic acid,98% RARECHEM AL BO 0089 (+/-)-2-PHENYLPROPIONIC ACID 2-PHENYLPROPIONIC ACID α-methylbenzeneaceticacid α-methylphenylaceticacid TIMTEC-BB SBB007855 a-Methylphenylacetic acid ALPHA-METHYLPHENYLACETIC ACID HYDRATROPIC ACID 95% (GC) (+/-)-2-Phenylpropionicacid,98% 2-Phenylpropionic (+/-)-HYDRATROPIC ACID DL-HYDRATROPIC ACID DL-2-PHENYLPROPIONIC ACID DL-2-Phenylpropionic acid, 98% 10GR 2-Phenylpropionic Acid, 97+% (RS)-2-phenylpropionicacid alpha-Methylbenzeneacetic acid alpha-methyl-benzeneaceticaci alpha-Phenylpropionic acid benzeneaceticacid,α-methyl- dl-alpha-Phenylpropionic acid Propanoic acid, 2-phenyl (2S)-2-phenylpropanoate DL-2-PhenylpropionicAcid> Benzeneacetic acid, .alpha.-methyl- (±)-2-Phenylpropionic acid, (±)-Hydratropic acid HYDRATROPIC ACID (±)-α-methylphenylaceticacid 2-Phenylproplonic Acid 2-pronyl propionic acid Benzeneacetic acid, α-methyl- 492-37-5 CH3CHC6H5COOH C6H5CHCH3COOH Carbonyl Compounds C9 Carboxylic Acids Building Blocks Organic Building Blocks CARBOXYLIC ACID Carboxylic Acids Aliphatics Carboxylic Acids Organic acids Pharmaceutical Intermediates