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Indirubin

Description References
Indirubin
Indirubin structure
CAS No.
479-41-4
Chemical Name:
Indirubin
Synonyms
c.i.73200;INDIRUBIN;C.I.75790;Nsc105327;INDIGO RED;Isoindogotin;INDIGOPURPURIN;COUROUPITINE B;INDIRUBIN (RG);Indirubin 479-41-4
CBNumber:
CB9296505
Molecular Formula:
C16H10N2O2
Formula Weight:
262.26
MOL File:
479-41-4.mol

Indirubin Properties

Melting point:
350°C(lit.)
Boiling point:
496.6±45.0 °C(Predicted)
Density 
1.417±0.06 g/cm3(Predicted)
storage temp. 
-20°C
pka
9.13±0.20(Predicted)
form 
Purple powder.
λmax
540nm(DMSO)(lit.)
CAS DataBase Reference
479-41-4(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
RTECS  DU2995000
HS Code  29339900

Indirubin price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL89716 Indirubin phyproof? Reference Substance 479-41-4 10mg $316 2019-12-02 Buy
TCI Chemical I0868 Indirubin >97.0%(HPLC) 479-41-4 25mg $250 2019-12-02 Buy
Cayman Chemical 14155 Indirubin ≥98% 479-41-4 5mg $48 2018-11-13 Buy
Cayman Chemical 14155 Indirubin ≥98% 479-41-4 10mg $91 2018-11-13 Buy
Cayman Chemical 14155 Indirubin ≥98% 479-41-4 25mg $204 2018-11-13 Buy

Indirubin Chemical Properties,Uses,Production

Description

Indirubin is the active ingredient of Danggui Longhui Wan, a traditional Chinese medicine containing plants such as Indigofera tinctoria L. and Isatis tinctoria L, which are used in traditional Chinese medicine to treat chronic diseases. Indirubin and its analogues are reported as potent inhibitors of cyclin-dependent kinases (CDKs). This could attribute to the positive effect of indirubin on counteracting proliferative diseases, such as chronic myelocytic leukemia (CML), a slowly progressive disease characterized by the overproduction of granulocytes.

References

[1] Tina Bla?evi?, Elke H. Heiss, Atanas G. Atanasov, Johannes M. Breuss, Verena M. Dirsch and Pavel Uhrin, Indirubin and Indirubin Derivatives for Counteracting Proliferative Diseases, Evidence-Based Complementary and Alternative Medicine, 2015, vol. 2015, Article ID 654098
[2] Ralph Hoessel, Sophie Leclerc, Jane A. Endicott, Martin E. M. Nobel, Alison Lawrie, Paul Tunnah, Maryse Leost, Eve Damiens, Dominique Marie, Doris Marko, Ellen Niederberger, Weici Tang, Gerhard Eisenbrand and Laurent Meijer, Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases, Nature Cell Biology, 1999, vol. 1, 60-67

Uses

Indigopurpurin is a purple 3,2-bisindole derivative and was shown to exhibit inhibitory allergic contact dermatitis via regulating T helper (Th)-mediated immune system in DNCB-induced model.

Uses

An inhibitor of GSK-3β and cyclin-dependent kinases.

Indirubin Preparation Products And Raw materials

Raw materials

Preparation Products


Indirubin Suppliers

Global( 226)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32447 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3015 60
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24191 60
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29995 58
Chengdu Biopurify Phytochemicals Ltd.
18080483897
maggie@biopurify.com CHINA 2368 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768
sales@dolonchem.com CHINA 2972 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
Changzhou PBpharmaceutical R&D Co.,Ltd
0519-83990708
info@pbpharm.com CHINA 498 58

View Lastest Price from Indirubin manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-10-08 Indirubin
479-41-4
US $0.00 / mg 5mg ≥97%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
2019-10-08 Indirubin
479-41-4
US $0.00 / mg 5mg Analytical Standard 10 g Shanghai Standard Technology Co., Ltd.
2019-07-10 Indirubin 479-41-4
479-41-4
US $12.50 / mg 20mg ≥98% 1000.00 kgs NanJing Spring & Autumn Biological Engineering CO., LTD.

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