DBCO-S-S-SE
- CAS No.
- Chemical Name:
- DBCO-S-S-SE
- Synonyms
- DBCO-S-S-SE;DBCO-S-S-NHS ester;DBCO-S-S-succinimidyl ester;Dibenzocyclooctyne-S-S-N-hydroxysuccinimidyl ester
- CBNumber:
- CB92984369
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD22380758
- MOL File:
- Mol file
DBCO-S-S-SE Chemical Properties,Uses,Production
Uses
Cleavable succinimidyl ester/NHS functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The disulfide present can be readily cleaved using mild reducing conditions (10-50 mM DTT at 37°C for 30 min or 5% ?-mercaptoethanol in SDS-PAGE sample buffer at 100°C for 5 minutes).
Caution: Please avoid reducing agents and amine or azide containing buffers during coupling/labeling reactions. Only use reducing agents when cleavage of the disulfide is desired.
DBCO-S-S-SE Preparation Products And Raw materials
Raw materials
Preparation Products
DBCO-S-S-SE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Shanghai Jiange Chemical Co., Ltd. | 15921040873 | 1434142450@qq.com | CHINA | 7651 | 58 |
Supplier | Advantage |
---|---|
Wuhan Borenpharm Co., Ltd | 58 |
Sigma-Aldrich | 80 |
Shanghai Jiange Chemical Co., Ltd. | 58 |