ChemicalBook >> CAS DataBase List >>CALPAIN INHIBITOR II
CALPAIN INHIBITOR II
- CAS No.
- 110115-07-6
- Chemical Name:
- CALPAIN INHIBITOR II
- Synonyms
- ALLM;Calp II;SUAM 312;AC-LLM-CHO;Ac-Leu-Leu-Met-al;AC-LEU-LEU-MET-CHO;CALPAIN INHIBITOR II;AC-LEU-LEU-METHIONINAL;AC-LEU-LEU-MET-ALDEHYDE;N-ACETYL-LEU-LEU-MET-CHO
- CBNumber:
- CB9305494
- Molecular Formula:
- C19H35N3O4S
- Molecular Weight:
- 401.56
- MDL Number:
- MFCD00065506
- MOL File:
- 110115-07-6.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:16
| Boiling point | 676.5±55.0 °C(Predicted) |
|---|---|
| Density | 1.076±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | ethanol: 20 mg/mL |
| form | powder |
| pka | 13.32±0.46(Predicted) |
| color | white |
| CAS DataBase Reference | 110115-07-6(CAS DataBase Reference) |
| FDA UNII | 1D8SBU367Z |
CALPAIN INHIBITOR II price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A6060 | Calpain Inhibitor II powder | 110115-07-6 | 5mg | $134 | 2024-03-01 | Buy |
| Sigma-Aldrich | A6060 | Calpain Inhibitor II powder | 110115-07-6 | 25mg | $561 | 2024-03-01 | Buy |
| Sigma-Aldrich | 208721 | ALLM - CAS 110115-07-6 - Calbiochem | 110115-07-6 | 25mg | $303 | 2024-03-01 | Buy |
| Cayman Chemical | 15994 | Calpain Inhibitor II ≥98% | 110115-07-6 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 15994 | Calpain Inhibitor II ≥98% | 110115-07-6 | 5mg | $78 | 2024-03-01 | Buy |
CALPAIN INHIBITOR II Chemical Properties,Uses,Production
Chemical Properties
white to off-white powder
Uses
Calpain inhibitor II is a cell-permeable peptide that restricts the activity of calpain, cathepsin L and cathepsin B. Calpain inhibitor II also prevents the methylmercury-induced cell death of cultured rat cerebellar neurons.
Definition
ChEBI: N-Acetylleucyl-leucyl-methioninal is a peptide.
General Description
A cell-permeable inhibitor of calpain I (Ki = 120 nM), calpain II (Ki = 230 nM), cathepsin B (Ki = 100 nM), and cathepsin L (Ki = 0.6 nM). Inhibits activation-induced programmed cell death and restores defective immune responses in HIV+ donors. Also prevents nitric oxide produced by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene.
Biochem/physiol Actions
Calpain is a cysteine protease expressed in the nervous system. Calpain exhibits a calcium-dependent enzyme activity. In mice models, inhibition of calpain prevents leukocyte infiltration induced by angiotensin II and also attenuates prevascular inflammation.
CALPAIN INHIBITOR II Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 106)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alpha Biopharmaceuticals Co., Ltd | +86-411-39042497 +8613921981412 | sales@alphabiopharm.com | China | 886 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
| Nanjing TGpeptide | +86-13347807150 +86-13347807150 | support@tgpeptide.com | China | 3279 | 58 |
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32360 | 55 |
| Chemwill Asia Co.,Ltd. | 86-21-51086038 | chemwill_asia@126.com | CHINA | 23931 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
View Lastest Price from CALPAIN INHIBITOR II manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-02-13 | CALPAIN INHIBITOR II
110115-07-6
|
US $7.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- CALPAIN INHIBITOR II
110115-07-6
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
110115-07-6(CALPAIN INHIBITOR II)Related Search:
Bismuth hydroxide nitrate oxide, BiO5.1
CALPAIN INHIBITOR I
Calpain Inhibitor I
CALPAIN INHIBITOR II
H-TRP-TRP-GLY-TRP-GLY-THR-MET-LEU-LEU-GLY-LEU-LEU-MET-ILE-CYS-OH
GTMLLGLLMICSATE
H-LEU-GLY-LEU-LEU-MET-ILE-CYS-SER-ALA-THR-GLU-LYS-LEU-TRP-VAL-OH
FUSION GLYCOPROTEIN (92-106) [HUMAN RESPIRATORY SYNCYTIAL VIRUS]
BIOTINYL-NEUROPEPTIDE W-23 (HUMAN)
CALPAIN INHIBITOR II (N-AC-LEU-LEU METHIORINAL)
H-TRP-TYR-LYS-HIS-VAL-ALA-SER-PRO-ARG-TYR-HIS-THR-VAL-GLY-ARG-ALA-SER-GLY-LEU-LEU-MET-GLY-LEU-OH
EUKARYOTIC TRANSLATION INITIATION FACTOR 3, SUBUNIT 3 GAMMA (242-250) [HOMO SAPIENS]/[RATTUS NORVEGICUS]
H2N-SLLMWITQV-OH
ALPHA-1 ANTITRYPSIN FRAGMENT [HOMO SAPIENS]/[PAPIO HAMADRYAS]/[CERCOPITHECUS AETHIOPS]
BIOT-PKPPKPVSKMRMATPLLMQA-OH
1of4
AC-LLM-CHO
AC-LEU-LEU-L-METHIONINAL
AC-LEU-LEU-MET-ALDEHYDE
AC-LEU-LEU-MET-CHO
AC-LEU-LEU-MET-H (ALDEHYDE)
AC-LEU-LEU-METHIONINAL
ALLM
N-AC-LEU-LEU-METHIONINAL
N-ACETYL-LEU-LEU-MET-CHO
N-ACETYL-LEU-LEU-METHIONINAL
N-ACETYL-L-LEUCYL-L-LEUCYL-L-METHIONAL
N-ACETYL-L-LEUCYL-L-LEUCYL-L-METHIONINAL
Ac-Leu-Leu-Met-al
N-Acetyl-L-Leu-L-Leu-L-Met-OH
Calpain Inhibitor II,96%
CALPAIN INHIBITOR II ;AC-LEU-LEU-MET-CHO
Calp II
SUAM 312
CALPAIN INHIBITOR II
ACETYL-L-LEUCYL-L-LEUCYL-L-METHIONINAL
n-acetylleucyl-leucyl-methioninal
L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-
ALLM (Calpain inhibitor II)
110115-07-6
C19H35N3O4S
Biochemicals and Reagents
BioChemical
A to C
Calpain I
Enzymes, Inhibitors, and Substrates
Enzyme Inhibitors by Enzyme
Enzyme Inhibitors
Pepetides
peptides
inhibitor