ANTI-MAFB
- CAS No.
- Chemical Name:
- ANTI-MAFB
- Synonyms
- ANTI-MAFB;Anti-KRML;Anti-MGC43127;ANTI-MAFB RABBIT PAB;Anti-Transcription factor MafB;Anti-MAFB antibody produced in rabbit;Anti-MAFB (AB1) antibody produced in rabbit;Anti-MAFB (AB2) antibody produced in rabbit;Anti-V-maf musculoaponeurotic fibrosarcoma oncogene homolog B;Anti-V-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
- CBNumber:
- CB9307867
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD07370390
- MOL File:
- Mol file
ANTI-MAFB price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | HPA005653 | Anti-MAFB antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $294 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB2101415 | Anti-MAFB antibody produced in rabbit affinity isolated antibody | 100μL | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA005653 | Anti-MAFB antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $547 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB2108488 | Anti-MAFB affinity isolated antibody | 100μL | $503 | 2023-01-07 | Buy | |
| Sigma-Aldrich | AV33682 | Anti-MAFB (AB2) antibody produced in rabbit IgG fraction of antiserum | 100μL | $425 | 2023-01-07 | Buy |
ANTI-MAFB Chemical Properties,Uses,Production
Uses
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
General Description
Musculoaponeurotic fibrosarcoma oncogene homolog B (MafB) is a transcription factor which is present in a wide variety of tissues and has 311 amino acids containing a typical bZip motif in its carboxy-terminal region.
Biochem/physiol Actions
Musculoaponeurotic fibrosarcoma oncogene homolog B (MafB) forms a homodimer through its leucine repeat structure and specifically binds to Maf-recognition elements (MAREs). It forms heterodimers with v-Maf and Fos through its zipper structure and acts as a transactivator for a promoter linked to MAREs. Through formation of numerous bZip dimers, MafB along with the AP-1 components provide great diversity in transcriptional regulation for a wide variety of genes. MafB is specifically expressed in myelomonocytic cells and binds to the DNA-binding domain of v-ets avian erythroblastosis virus E26 oncogene homolog 1 (Ets-1) by its leucine–zipper domain. It also represses Ets-1 transactivation of promoters containing Ets binding sites and inhibits Ets-1–mediated transactivation of the transferrin receptor, which is known to be essential for erythroid differentiation. Overexpression of MafB in an erythroblast cell line down-regulates the endogenous transferrin receptor gene and inhibits differentiation without affecting cell proliferation.
ANTI-MAFB Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-MAFB Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |