ChemicalBook
Chinese Japanese Germany Korea

Oxytetracycline hydrochloride

Oxytetracycline hydrochloride
Oxytetracycline hydrochloride structure
CAS No.
2058-46-0
Chemical Name:
Oxytetracycline hydrochloride
Synonyms
OTC;tm5;nsc9169;mepatar;TOXINAL;otetryn;oxlopar;GEOMYCIN;Oxycycin;Oxycline
CBNumber:
CB9311671
Molecular Formula:
C22H25ClN2O9
Formula Weight:
496.89
MOL File:
2058-46-0.mol

Oxytetracycline hydrochloride Properties

Melting point:
180°C
alpha 
-188~-200°(D/20℃)(c=1,0.1mol/l HCl) (calculated on the dried basis)
storage temp. 
0-6°C
solubility 
Freely soluble in water, sparingly soluble in ethanol (96 per cent). Solutions in water become turbid on standing, owing to the precipitation of oxytetracycline.
form 
crystalline
color 
yellow
PH
2.0~3.0 (10g/l, 25℃)
Water Solubility 
>100 g/L
Sensitive 
Light Sensitive
λmax
360nm(H2O)(lit.)
Merck 
14,6976
BRN 
3853107
CAS DataBase Reference
2058-46-0(CAS DataBase Reference)
EPA Substance Registry System
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5, 5a,6,11,12a-octahydro-3,5, 6,10,12,12a-hexahydroxy-6- methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6S,12aS)-(2058-46-0)

SAFETY

Hazard Codes  Xn,Xi
Risk Statements  63-36-36/37/38
Safety Statements  36/37/39-26-36-36/37
RIDADR  UN 3077 9/PG III
WGK Germany  2
RTECS  QI8225000
8-10-23
TSCA  Yes
HazardClass  9
PackingGroup  III
HS Code  29413000

Oxytetracycline hydrochloride price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich O5875 Oxytetracycline hydrochloride ≥95% (HPLC), crystalline 2058-46-0 10g $52.5 2018-11-20 Buy
Sigma-Aldrich 1491015 Oxytetracycline hydrochloride United States Pharmacopeia (USP) Reference Standard 2058-46-0 200mg $352.8 2018-11-20 Buy
TCI Chemical O0475 Oxytetracycline Hydrochloride >95.0%(HPLC)(T) 2058-46-0 5g $28 2018-11-22 Buy
TCI Chemical O0475 Oxytetracycline Hydrochloride >95.0%(HPLC)(T) 2058-46-0 25g $83 2018-11-22 Buy
Alfa Aesar J62489 Oxytetracycline hydrochloride 2058-46-0 100g $183 2018-11-13 Buy

Oxytetracycline hydrochloride Chemical Properties,Uses,Production

Chemical Properties

Yellow Crystalline Solid

Uses

Antibiotic substance isolated from the elaboration products of the actinomycete, Streptomyces rimosus, grown on a suitable medium. Antibacterial

Uses

Oxytetracycline hydrochloride is a salt prepared from oxytetracycline taking advantage of the basic dimethylamino group which protonates readily to form the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, oxytetracycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.

brand name

Terramycin (Pfizer).

General Description

Early in 1950, Finlay et al.182 reported the isolation of oxytetracycline(Terramycin) from S. rimosus. This compoundwas soon identified as a chemical analog of chlortetracycline that showed similar antibiotic properties. The structureof oxytetracycline was elucidated by Hochstein et al.183 andthis work provided the basis for the confirmation of thestructure of the other tetracyclines.
Oxytetracycline hydrochloride is a pale yellow, bitter,crystalline compound. The amphoteric base is only slightlysoluble in water and slightly soluble in alcohol. It is odorlessand stable in air but darkens on exposure to strong sunlight.The hydrochloride salt is a stable yellow powder that ismore bitter than the free base. It is much more soluble inwater, 1 g dissolving in 2 mL, and more soluble in alcoholthan the free base. Both compounds are inactivated rapidlyby alkali hydroxides and by acid solutions below pH 2. Bothforms of oxytetracycline are absorbed rapidly and equallywell from the digestive tract, so the only real advantage thefree base offers over the hydrochloride salt is that it is lessbitter. Oxytetracycline hydrochloride is also used for parenteraladministration (intravenously and intramuscularly).

General Description

Odorless fluffy yellow solid or yellow powder. Bitter taste.

Air & Water Reactions

Oxytetracycline hydrochloride is hygroscopic. Water soluble. Undergoes slow hydrolysis in the presence of water. Concentrated aqueous solutions at neutral pH hydrolyze on standing.

Reactivity Profile

Oxytetracycline hydrochloride is sensitive to light. Oxytetracycline hydrochloride may be unstable at temperatures above 77° F. Oxytetracycline hydrochloride darkens on exposure to sunlight or to moist air above 194° F. Concentrated aqueous solutions at neutral pH hydrolyze on standing. Oxytetracycline hydrochloride undergoes hydrolysis in the presence of water. Oxytetracycline hydrochloride may be incompatible with alkalis.

Fire Hazard

Flash point data for Oxytetracycline hydrochloride are not available. Oxytetracycline hydrochloride is probably combustible.

Oxytetracycline hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products


Oxytetracycline hydrochloride Suppliers

Global( 269)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Hebei Guanlang Biotechnology Co., Ltd.
+86-0311-66562153 whatsapp +8615203118427
+86-0311-66562153 sales@crovellbio.com CHINA 407 50
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21922 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
PI & PI BIOTECH INC.
020-81716320
020-81716319 Sales@pipitech.com CHINA 2543 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012 sales03@shyrchem.com CHINA 661 60
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 541 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
Hebei Chisure Biotechnology Co., Ltd.
+8613091036086; +8613292890173
+8613292893290 sandy@speedgainpharma.com; luna@speedgainpharma.com CHINA 1019 58

View Lastest Price from Oxytetracycline hydrochloride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-04-02 Oxytetracycline hydrochloride
2058-46-0
US $10.00 / KG 100g 99% 10tons Hebei Jimi Trading Co., Ltd.

2058-46-0(Oxytetracycline hydrochloride)Related Search:


  • hydrocyclin
  • liquamycininjectable
  • mepatar
  • nsc9169
  • 5-hydroxytetracycline hydrochloride
  • [4s-(4alpha,4aalpha,5alpha,5aalpha,6beta,12aalpha)]-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride
  • GEOMYCIN
  • AQUACYCLINE
  • BIO-MYCIN
  • OXYTETRACYCLINE HCL
  • OXYTETRACYCLINE HYDROCHLORIDE
  • OTC
  • TOXINAL
  • TETRAMYCIN
  • OXYTETRACYCLINE HCL BP/USP
  • Oxyctracycline HCL compacted
  • OXYTETRACYCLINE HYDROCHLORIDE VETR
  • OXYTETRACYCLINE HYDROCHLORIDE YELLOW CRYSTALS
  • OxytetracyclineHydrochlorideB.P.
  • OXYTETRACYCLIN HYDROCHLORIDE
  • Oxytetracycline hydrochloride, can be used as secondary standard'
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aR,5S,5aR,6S,12aS)-
  • OXYTETRACYCLINEHYDROCHLORIDE,EP
  • OXYTETRACYCLINE HCl79-57-2
  • MONOHYDROCHLORIDEHYDROXYTETRACYCLINE
  • HYDROXYTETRACYCLINEMONOHYDROCHLORIDE
  • 5-Hydroxytetracycline hydrochlride, TerraMycin hydrochloride, Oxytetrin, Tetran hydrochloride
  • Oxytetracycline hydrochloride Solution, 100ppm
  • 2058-46-0
  • C22H24N2O9HCl
  • Oligomycin HCL
  • Oxyteracycline HCL
  • Oxytetracycline hydrochloride≥ 97.5% (anhydrous assay)
  • 10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-monohydrochloride
  • 2-naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,
  • 5alpha,5aalpha,6beta,12aalpha)]-aalph
  • 6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,monohydrochloride,[4s-(4alpha,4
  • biosolvomycin
  • engemycin
  • Oxycycin
  • otetryn
  • oxlopar
  • oxyject100
  • oxytetrin
  • terramycinhydrochloride
  • tetranhydrochloride
  • tm5
  • GLOBETERRAMYCINPETTABS
  • oxytetracyine hydrochloride
  • [4S-(4a,4aa,5a,5aa,6,12aa]-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
  • Oxycline
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aR,5S,5aR,6S,12aS)-
  • Oxytetra Cone
  • Oxytetracycline hydrochloride Standard
  • OXYTETRACYCLINE.HCLRESEARCH GRADE
  • Oxytetracycline Hydrochloride (200 mg)
  • Oxytetracycline Hydrochloride (200 mg) (AS)
  • Oxytetracycline Hydrochloride DISCONTINUED. See O877501
Copyright 2017 © ChemicalBook. All rights reserved