ChemicalBook >> CAS DataBase List >>Sacubitril Impurity

Sacubitril Impurity

CAS No.
1015037-46-3
Chemical Name:
Sacubitril Impurity
Synonyms
impurity 41;Sacubitril Impurity;Sacubitril Impurity 103;LCZ696 valsartan + sacubitril impurity 41;(S,E)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid;(2E,4S)-5-[1,1-Biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-pentenoic Acid;(2E,4S)-5-[1,1'-Biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-pentenoic acid;2-Pentenoic acid, 5-[1,1'-biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-, (2E,4S)-
CBNumber:
CB93122683
Molecular Formula:
C23H27NO4
Molecular Weight:
381.46
MDL Number:
MFCD28386957
MOL File:
1015037-46-3.mol
Last updated:2025-07-16 09:55:26

Sacubitril Impurity Properties

Boiling point 595.6±50.0 °C(Predicted)
Density 1.132±0.06 g/cm3(Predicted)
storage temp. Storage temp. 2-8°C
pka 4.67±0.19(Predicted)
Appearance White to off-white Solid
InChI InChI=1S/C23H27NO4/c1-16(21(25)26)14-20(24-22(27)28-23(2,3)4)15-17-10-12-19(13-11-17)18-8-6-5-7-9-18/h5-14,20H,15H2,1-4H3,(H,24,27)(H,25,26)/b16-14+/t20-/m1/s1
InChIKey JXTNUXJSXXIIFE-KETLNSEPSA-N
SMILES C(O)(=O)/C(/C)=C/[C@@H](NC(OC(C)(C)C)=O)CC1=CC=C(C2=CC=CC=C2)C=C1

Sacubitril Impurity Chemical Properties,Uses,Production

Uses

(2E,4S)-5-[1,1''-Biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-pentenoic Acid was used in the study to process for preparation of biaryl-substituted 4-aminobutyric acids by hydrogenation of the corresponding alkenoates.

Sacubitril Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

Sacubitril Impurity Suppliers

Global( 45)Suppliers
Supplier Tel Email Country ProdList Advantage
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Moxin Chemicals
+86-17320513646 +8617320513646 anna@molcoo.com China 10000 58
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.
+undefined18603013401 jack.lin@sincopharmachem.com China 9999 58
Suzhou Hengning Pharmaceutical Technology Co., Ltd. 0512-65649061 17365378613 hengningpharma@163.com China 150 58
Jiangsu Vcare PharmaTech Co., Ltd. 025-58741518 13327700685 sales@vcarepharmatech.com China 296 61
Quality Control Solutions Ltd. 66853366 13670046396 sales@chem-strong.com China 18390 56
Nanjing XiZe Biotechnology CO., Ltd. 025-58362220 0086-15250997978 sale@njxizebio.com China 4862 55
Suzhou PengXu PharmaTech Co., Ltd. 15850786624 sales@cqpharm.com China 88 58
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@yongstandards.com China 9999 55
(2E,4S)-5-[1,1-Biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-pentenoic Acid 2-Pentenoic acid, 5-[1,1'-biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-, (2E,4S)- impurity 41 Sacubitril Impurity (S,E)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoic acid Sacubitril Impurity 103 (2E,4S)-5-[1,1'-Biphenyl]-4-yl-4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-methyl-2-pentenoic acid LCZ696 valsartan + sacubitril impurity 41 1015037-46-3