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2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

CAS No.
37052-78-1
Chemical Name:
2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
Synonyms
5-METHOXY-1H-BENZO[D]IMIDAZOLE-2-THIOL;Omeprazole Impurity A;OMeprazole Related CoMpound B;5-METHOXY-2-BENZIMIDAZOLETHIOL;5-METHOXY-2-MERCAPTOBENZIMIDAZOLE;5-methoxy-1H-benzoimidazole-2-thiol;H 118/87;5-Methoxy;OMEP IM-A;TIMTEC-BB SBB000219
CBNumber:
CB9313620
Molecular Formula:
C8H8N2OS
Molecular Weight:
180.23
MDL Number:
MFCD00134581
MOL File:
37052-78-1.mol
MSDS File:
SDS
Modify Date:2022-08-23 14:33:43

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Properties

Melting point 261-263 °C(lit.)
Boiling point 309.4±44.0 °C(Predicted)
Density 1.2425 (rough estimate)
refractive index 1.5690 (estimate)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Sparingly)
pka 10.13±0.30(Predicted)
form Powder
color Off-white to light yellow-brown
Water Solubility insoluble
Sensitive Air Sensitive
BRN 3605123
CAS DataBase Reference 37052-78-1(CAS DataBase Reference)
FDA UNII 143562LXX0

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-37-22
Safety Statements  26-36
WGK Germany  3
HazardClass  IRRITANT
HS Code  29332900
NFPA 704
1
2 0

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 382485 5-Methoxy-2-benzimidazolethiol 99% 37052-78-1 5g $30 2022-05-15 Buy
Sigma-Aldrich 1478480 Omeprazole Related Compound B United States Pharmacopeia (USP) Reference Standard 37052-78-1 15mg $1270 2022-05-15 Buy
TCI Chemical M1256 2-Mercapto-5-methoxybenzimidazole >98.0%(HPLC)(T) 37052-78-1 25g $85 2022-04-27 Buy
Alfa Aesar B20570 2-Mercapto-5-methoxybenzimidazole, 99% 37052-78-1 5g $26.1 2021-12-16 Buy
Alfa Aesar B20570 2-Mercapto-5-methoxybenzimidazole, 99% 37052-78-1 25g $89.2 2021-12-16 Buy
Product number Packaging Price Buy
382485 5g $30 Buy
1478480 15mg $1270 Buy
M1256 25g $85 Buy
B20570 5g $26.1 Buy
B20570 25g $89.2 Buy

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Chemical Properties,Uses,Production

Description

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2[[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfonyl]-1H-benzimidazole, 5-methoxy-2[[(4-methoxy-3, 5-dimethylpyridin-2-yl-1-oxide) methyl] sulfonyl]-1H-benzimidazole as well as tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate. Furthermore, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole1. Finally, it acts as an intermediate for manufacture of the anti-ulcer drug Omeprazole.

Chemical Properties

off-white to light yellowish-brown powder

Uses

5-Methoxy-2-benzimidazolethiol may be used in the preparation of compounds present as contaminants in omeprazole, such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. It may be used in the synthesis of tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate.

Uses

Reagent used in the synthesis of COX-2 inhibitors

Uses

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 646)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29803 60
Henan DaKen Chemical CO.,LTD.
+86-371-66670886 info@dakenchem.com China 16708 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 22021 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1809 55
Guangzhou PI PI Biotech Inc
+86-020-81716320 +86-18371201331 Sales@pipitech.com China 3640 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29960 58
Zhejiang ZETian Fine Chemicals Co. LTD
18957127338 stella@zetchem.com China 2011 58
Shenzhen Nexconn Pharmatechs Ltd
15013857715 admin@nexconn.com CHINA 3004 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 4430 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254 linda@hubeijusheng.com CHINA 28229 58

View Lastest Price from 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2022-09-21 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
37052-78-1
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
2022-09-08 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
37052-78-1
US $20.00 / kg 1kg 99% 5000 Ton Hebei Duling International Trade Co. LTD
2022-02-25 5-Methoxy-2-mercaptobenzimidazole
37052-78-1
US $0.00 / Kg/Drum 1ASSAYS 99% 50mt Jinan Finer Chemical Co., Ltd
5-Methoxye-2-mercaplobenzinidazole TIMTEC-BB SBB000219 5-Methoxybenzimidazole-2-thiol 5-METHOXY-2-THIOBENZIMIDAZOLE 2-MERCAPTO-5-METHOXY-1H-BENZIMIDAZOLE 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE 1,3-DIHYDRO-5-METHOXY-2H-BENZIMIDAZOLE-2-THIONE LABOTEST-BB LT01596137 H 118/87 5-methoxy-2(1H)-benzimidazolinethione 2-Mercato-5-methoxy benzimidazole 5-METHOXY-2-THIOHYDROXYBENZIMIDAZOLE(INTERMEDIATE OF OMEPRAZOLE) 2-Mercapto-5-MethoxyBenzimidazole(ForOmeprazole) 5-METHOXY-2-BENZIMIDAZOLEETHIOL 2-Mercapto-5-methoxy-1H-benzim 5-methoxy-2-thiohydroxy benzimidazole 5-Methoxy-2-thiobenzimidazole 99% 2H-Benzimidazole-2-thione,1,3-dihydro-5-methoxy-(9CI) 5-METHOXY-2-MERCAPTOBENIMIDAZOLEOMEPRAZOLE 5-METHOXYL-2-MERCAPTOBENZIMIDAZOLE 5-Methoxy-1H-1,3-benzodiazole-2-thiol 5-Methoxy-1,3-dihydrobenzimidazole-2-thione 5-Methoxy-2-benzimidazolethiol ,99% 5-METHOXY-2-MERCAPTOBENZIMIDAZOLE, 99+% 6-Methoxy-1H-benzimidazole-2-thiol 6-Methoxy-2-mercapto-1H-benzimidazole 5-Methoxy-2-mercapto 5-Methoxy-1H-benzimidazole-2-thiol 99% (S)-Omeprazole Intermediate 2 Omeprazole EP impurity-A (USP RC B) Esomeprazole impurity A Omeprazole Imp. A(EP)(USP RC B): (5-Methoxy-1H-Benzimidazole-2-Thiol) 2-mercapto-5-methyoxy benzimidazole (omeprazole-benzimidazole) 5-DIFLUOROMETHOXY-2-MERCAPTO- BENZIMIDZO LE Omeprazole RCB (USP) EsoMeprazole related substance A EsoMeprazol iMpurity A OMeprazole IMpurity-A (EP) OMeprazole EP IMpurity A 5-Methoxy-1H-benzimidazole-2-thiol, 2-Mercapto-5-methoxy-1H-benzimidazole 5-Methoxy-2-thio-1H-benzimidazole 99% 5-Methoxy-1H-benzo[d]iMidazole-2(3H)-thione OMeprazole IMpurity A (5-Methoxy-1H-BenziMidazole-2-Thiol) 5-Methoxy-1H-benzo[d]iMidazole-2-thiol (RelCpd A) 2H-BenziMidazole-2-thione, 1,3-dihydro-5-Methoxy- 2-Mercatto-5-Methoxy-1H-BenziMidazde 5-Methoxy-2-benziMidazolethiol 99% 5-Methoxy-2-mercaptobenzimidazole 5-Methoxybenzimidazole-2-thiol 5-Methoxy-2-mercaptobenzimidazole 5-Methoxy-2-benzimidazolethiol Esomeprazole Magnesium Trihydrate Imp. A (EP): 5-Methoxy-1H-benzimidazole-2-thiol Esomeprazole EP Impurity A 2-Mercapoto-5-Methoxy-1H-benzimidazole Esomeprazole Sodium Impurity Ⅴ:5-Methoxy-2-mercaptobenzimidazole 5-Methoxy 5-Methoxy-2-thio-1H-benzimidazole Esomeprazol EP Impurity A(Omeprazole EP Impurity A) 2-MERCAPTO -5-METHOXY BENZIMIDAZOLE (METOXITIONA ) OMEP IM-A