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ChemicalBook >> CAS DataBase List >>2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Structure
2-MERCAPTO-5-METHOXYBENZIMIDAZOLE structure
CAS No.
37052-78-1
Chemical Name:
2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
Synonyms
5-METHOXY-1H-BENZO[D]IMIDAZOLE-2-THIOL;Omeprazole Impurity A;OMeprazole Related CoMpound B;5-METHOXY-2-BENZIMIDAZOLETHIOL;5-METHOXY-2-MERCAPTOBENZIMIDAZOLE;5-methoxy-1H-benzoimidazole-2-thiol;H 118/87;5-Methoxy;OMEP IM-A;TIMTEC-BB SBB000219
CBNumber:
CB9313620
Molecular Formula:
C8H8N2OS
Molecular Weight:
180.23
MDL Number:
MFCD00134581
MOL File:
37052-78-1.mol
MSDS File:
SDS
Last updated:2024-04-17 18:50:11
Request For Quotation

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Properties

Melting point 261-263 °C(lit.)
Boiling point 309.4±44.0 °C(Predicted)
Density 1.2425 (rough estimate)
vapor pressure 0.001Pa at 25℃
refractive index 1.5690 (estimate)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Sparingly)
pka 10.13±0.30(Predicted)
form Powder
color Off-white to light yellow-brown
Water Solubility insoluble
Sensitive Air Sensitive
BRN 3605123
LogP 1.52-2.399
CAS DataBase Reference 37052-78-1(CAS DataBase Reference)
FDA UNII 143562LXX0

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-37-22
Safety Statements  26-36
WGK Germany  3
HazardClass  IRRITANT
HS Code  29332900
NFPA 704
1
2 0

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 382485 5-Methoxy-2-benzimidazolethiol 99% 37052-78-1 5g $52.7 2024-03-01 Buy
Sigma-Aldrich 1478480 Omeprazole Related Compound B United States Pharmacopeia (USP) Reference Standard 37052-78-1 15mg $1380 2024-03-01 Buy
TCI Chemical M1256 2-Mercapto-5-methoxybenzimidazole >98.0%(HPLC)(T) 37052-78-1 25g $90 2024-03-01 Buy
Alfa Aesar B20570 2-Mercapto-5-methoxybenzimidazole, 99% 37052-78-1 5g $26.65 2024-03-01 Buy
Alfa Aesar B20570 2-Mercapto-5-methoxybenzimidazole, 99% 37052-78-1 25g $94.3 2023-06-20 Buy
Product number Packaging Price Buy
382485 5g $52.7 Buy
1478480 15mg $1380 Buy
M1256 25g $90 Buy
B20570 5g $26.65 Buy
B20570 25g $94.3 Buy

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Chemical Properties,Uses,Production

Description

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2[[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfonyl]-1H-benzimidazole, 5-methoxy-2[[(4-methoxy-3, 5-dimethylpyridin-2-yl-1-oxide) methyl] sulfonyl]-1H-benzimidazole as well as tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate. Furthermore, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole1. Finally, it acts as an intermediate for manufacture of the anti-ulcer drug Omeprazole.

Chemical Properties

off-white to light yellowish-brown powder

Uses

5-Methoxy-2-benzimidazolethiol may be used in the preparation of compounds present as contaminants in omeprazole, such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. It may be used in the synthesis of tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate.

Uses

Reagent used in the synthesis of COX-2 inhibitors

Uses

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Flammability and Explosibility

Not classified

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

Ufiprazole Omeprazole 2-[(5-methoxy-1H-benzimidazol-2-yl)sulfanyl]-N-(2-nitrophenyl)acetamide

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Suppliers

Global( 747)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12453 58
Hebei Guanlang Biotechnology Co,.LTD 		+8619930503252 daisy@crovellbio.com China 5964 58
Anhui Ruihan Technology Co., Ltd 		+8617756083858 daisy@anhuiruihan.com China 994 58
Hebei Saisier Technology Co., LTD 		+86-18400010335 +86-13102810335 admin@hbsaisier.cn China 424 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15371 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Zhejiang ZETian Fine Chemicals Co. LTD 		18957127338 stella@zetchem.com China 2141 58
Supplier Advantage
Hebei Mojin Biotechnology Co., Ltd 		58
Hebei Guanlang Biotechnology Co,.LTD 		58
Anhui Ruihan Technology Co., Ltd 		58
Hebei Saisier Technology Co., LTD 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58

View Lastest Price from 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Methoxy-2-mercaptobenzimidazole pictures 2024-04-19 5-Methoxy-2-mercaptobenzimidazole
37052-78-1
 US $0.00 / Kg/Drum 1ASSAYS 99% 50mt Jinan Finer Chemical Co., Ltd
2-MERCAPTO-5-METHOXYBENZIMIDAZOLE pictures 2024-04-18 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
37052-78-1
 US $6.00 / KG 1KG More than 99% 2000KG/MONTH Hebei Saisier Technology Co., LTD
2-MERCAPTO-5-METHOXYBENZIMIDAZOLE pictures 2023-12-25 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
37052-78-1
 US $0.00 / kg 1kg 99% 1000000 Hebei Jingbo New Material Technology Co., Ltd

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Spectrum

2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)MS2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)1HNMR2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)13CNMR2-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)IR12-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)IR22-MERCAPTO-5-METHOXYBENZIMIDAZOLE(37052-78-1)Raman

37052-78-1(2-MERCAPTO-5-METHOXYBENZIMIDAZOLE)Related Search:

2-Ethylhexyl mercaptoacetate Mercaptoacetic acid 2-Mercaptobenzimidazole 2-Methoxyethanol Benzimidazole
2-Methylbenzimidazole 3-Mercaptopropionic acid Ufiprazole OMEPRAZOLE RELATED COMPOUND A (15 MG) (OMEPRAZOLE SULFONE) (AS) Calcium thioglycolate
Omeprazole 5-METHOXY-2-[((4-METHOXY-3,5-DIMETHYL-1-OXIDO-2-PYRIDINYL)METHYL)SULFINYL]-BENZIMIDAZOLE Esomeprazole Impurity 3 (S)-4-Desmethoxy-4-chloro Omeprazole 4-Hydroxy Omeprazole
Omeprazole EP Impurity F Omeprazole Sulfone N-Oxide EsoMeprazole related substance H431/41

1of4

5-Methoxye-2-mercaplobenzinidazole TIMTEC-BB SBB000219 5-Methoxybenzimidazole-2-thiol 5-METHOXY-2-THIOBENZIMIDAZOLE 2-MERCAPTO-5-METHOXY-1H-BENZIMIDAZOLE 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE 1,3-DIHYDRO-5-METHOXY-2H-BENZIMIDAZOLE-2-THIONE LABOTEST-BB LT01596137 H 118/87 5-methoxy-2(1H)-benzimidazolinethione 2-Mercato-5-methoxy benzimidazole 5-METHOXY-2-THIOHYDROXYBENZIMIDAZOLE(INTERMEDIATE OF OMEPRAZOLE) 2-Mercapto-5-MethoxyBenzimidazole(ForOmeprazole) 5-METHOXY-2-BENZIMIDAZOLEETHIOL 2-Mercapto-5-methoxy-1H-benzim 5-methoxy-2-thiohydroxy benzimidazole 5-Methoxy-2-thiobenzimidazole 99% 2H-Benzimidazole-2-thione,1,3-dihydro-5-methoxy-(9CI) 5-METHOXY-2-MERCAPTOBENIMIDAZOLEOMEPRAZOLE 5-METHOXYL-2-MERCAPTOBENZIMIDAZOLE 5-Methoxy-1H-1,3-benzodiazole-2-thiol 5-Methoxy-1,3-dihydrobenzimidazole-2-thione 5-Methoxy-2-benzimidazolethiol ,99% 5-METHOXY-2-MERCAPTOBENZIMIDAZOLE, 99+% 6-Methoxy-1H-benzimidazole-2-thiol 6-Methoxy-2-mercapto-1H-benzimidazole 5-Methoxy-2-mercapto 5-Methoxy-1H-benzimidazole-2-thiol 99% (S)-Omeprazole Intermediate 2 Omeprazole EP impurity-A (USP RC B) Esomeprazole impurity A Omeprazole Imp. A(EP)(USP RC B): (5-Methoxy-1H-Benzimidazole-2-Thiol) 2-mercapto-5-methyoxy benzimidazole (omeprazole-benzimidazole) 5-DIFLUOROMETHOXY-2-MERCAPTO- BENZIMIDZO LE Omeprazole RCB (USP) EsoMeprazole related substance A EsoMeprazol iMpurity A OMeprazole IMpurity-A (EP) OMeprazole EP IMpurity A 5-Methoxy-1H-benzimidazole-2-thiol, 2-Mercapto-5-methoxy-1H-benzimidazole 5-Methoxy-2-thio-1H-benzimidazole 99% 5-Methoxy-1H-benzo[d]iMidazole-2(3H)-thione OMeprazole IMpurity A (5-Methoxy-1H-BenziMidazole-2-Thiol) 5-Methoxy-1H-benzo[d]iMidazole-2-thiol (RelCpd A) 2H-BenziMidazole-2-thione, 1,3-dihydro-5-Methoxy- 2-Mercatto-5-Methoxy-1H-BenziMidazde 5-Methoxy-2-benziMidazolethiol 99% 5-Methoxy-2-mercaptobenzimidazole 5-Methoxybenzimidazole-2-thiol 5-Methoxy-2-mercaptobenzimidazole 5-Methoxy-2-benzimidazolethiol Esomeprazole Magnesium Trihydrate Imp. A (EP): 5-Methoxy-1H-benzimidazole-2-thiol Esomeprazole EP Impurity A 2-Mercapoto-5-Methoxy-1H-benzimidazole Esomeprazole Sodium Impurity Ⅴ:5-Methoxy-2-mercaptobenzimidazole 5-Methoxy 5-Methoxy-2-thio-1H-benzimidazole Esomeprazol EP Impurity A(Omeprazole EP Impurity A) 2-MERCAPTO -5-METHOXY BENZIMIDAZOLE (METOXITIONA ) OMEP IM-A