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Aprepitant Impurity 6

CAS No.
170902-81-5
Chemical Name:
Aprepitant Impurity 6
Synonyms
1S, 2R, 3S-Aripitan;Aprepitant Impurity 5(S,R,S-Isomer);Fosaprepitant Dimeglumine Impurity A;Arepitam impurity isomers (1S, 2R, 3S);Fosaprepitant Dimeglumine EP Impurity A;Aprepitant impurity 9/(1S,2R,3S)-Aprepitant;[1(S)-Phenylethoxy]-Aprepitant/ Aprepitant S,R,S-Isomer;5-([(2R,3S)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one;5-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one;3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-
CBNumber:
CB93146511
Molecular Formula:
C23H21F7N4O3
Molecular Weight:
534.43
MDL Number:
MOL File:
170902-81-5.mol

Aprepitant Impurity 6 Properties

Density 1.51±0.1 g/cm3(Predicted)
pka 8.06±0.20(Predicted)

Aprepitant Impurity 6 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P320780 [1(S)-Phenylethoxy]-Aprepitant 170902-81-5 1mg $125 2021-12-16 Buy
TRC P320780 [1(S)-Phenylethoxy]-Aprepitant 170902-81-5 10mg $1010 2021-12-16 Buy
Product number Packaging Price Buy
P320780 1mg $125 Buy
P320780 10mg $1010 Buy

Aprepitant Impurity 6 Chemical Properties,Uses,Production

Uses

[1(S)-Phenylethoxy]-Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1.

Aprepitant Impurity 6 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 37)Suppliers
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Standardpharm Co. Ltd.
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sgtlifesciences pvt ltd
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China National Standard Pharmaceutical Corporation Limited
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BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
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Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9911 50
Nanjing XiZe Biotechnology CO., Ltd. 025-58362220 15250997978 1511893459@qq.com China 7715 55
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@qq.com China 7851 55
Fosaprepitant Dimeglumine Impurity A Aprepitant Impurity 5(S,R,S-Isomer) Aprepitant impurity 9/(1S,2R,3S)-Aprepitant 1S, 2R, 3S-Aripitan Arepitam impurity isomers (1S, 2R, 3S) 5-([(2R,3S)-2-((S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy)-3-(4-fluoro phenyl)morpholino]methyl)-1H-1,2,4-triazol-3(2H)-one 3H-1,2,4-Triazol-3-one, 5-[[(2R,3S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro- Fosaprepitant Dimeglumine EP Impurity A 5-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one [1(S)-Phenylethoxy]-Aprepitant/ Aprepitant S,R,S-Isomer 170902-81-5