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Celecoxib Impurity

CAS No.
915280-81-8
Chemical Name:
Celecoxib Impurity
Synonyms
Celebrex O;Celecoxib-21;Celecoxib-008;Celecoxib Hydrazine;Celecoxib impurity O;Celecoxib Hydraziney;Celecoxib impurities1092;4-(2-(2,2,2-trifluoroacetyl);4-[2-(trifluoroacetyl)hydrazino]benzenesulfonamide;4-(2-(2,2,2-trifluoroacetyl)hydrazinyl)benzenesulfonamide
CBNumber:
CB93313564
Molecular Formula:
C8H8F3N3O3S
Molecular Weight:
283.23
MDL Number:
MFCD34596597
MOL File:
915280-81-8.mol
Last updated:2022-08-26 12:18:01

Celecoxib Impurity Properties

Density 1.603±0.06 g/cm3(Predicted)
pka 8.40±0.43(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301-H311-H331
Precautionary statements  P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501

Celecoxib Impurity Chemical Properties,Uses,Production

Uses

Celecoxib Hydraziney is an impurity of Celecoxib(C251000). Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.Celecoxib is used to treat pain or inflammation caused by many conditions such as arthritis, ankylosing spondylitis, and menstrual pain. Celecoxib is also used in the treatment of hereditary polyps in the colon.

Celecoxib Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(2-(2,2,2-trifluoroacetyl)hydrazinyl)benzenesulfonamide Celecoxib-008 4-(2-(2,2,2-trifluoroacetyl) Celecoxib-21 Celebrex O Acetic acid, 2,2,2-trifluoro-, 2-[4-(aminosulfonyl)phenyl]hydrazide Celecoxib Hydraziney Celecoxib impurity O Celecoxib impurities1092 4-[2-(trifluoroacetyl)hydrazino]benzenesulfonamide Celecoxib Hydrazine 915280-81-8