ChemicalBook >> CAS DataBase List >>LM22B-10
LM22B-10
- CAS No.
- 342777-54-2
- Chemical Name:
- LM22B-10
- Synonyms
- LM22B-10;2,2',2',2'''-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol;Ethanol, 2,2',2'',2'''-[[(4-chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakis-;2,2',2'',2'''-((((4-Chlorophenyl)methylene)bis(4,1-phenylene))bis(azanetriyl))tetrakis(ethan-1-ol);2-[[4-[[4-[BIS-(2-HYDROXYETHYL)-AMINO]-PHENYL]-(4-CHLORO-PHENYL)-METHYL]-PHENYL]-(2-HYDROXY-ETHYL)-AMINO]-ETHANOL;inhibit,Trk Receptor,Akt,LM-22B-10,LM22B-10,LM22B 10,Tropomyosin related kinase receptor,ERK,PKB,Inhibitor,Protein kinase B,Extracellular signal regulated kinases
- CBNumber:
- CB93356163
- Molecular Formula:
- C27H33ClN2O4
- Molecular Weight:
- 485.01
- MDL Number:
- MFCD00483554
- MOL File:
- 342777-54-2.mol
Last updated:2024-07-02 08:55:42
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 |
LM22B-10 price More Price(20)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML2461 | LM22B-10 ≥98% (HPLC) | 342777-54-2 | 5mg | $102 | 2024-03-01 | Buy |
Sigma-Aldrich | SML2461 | LM22B-10 ≥98% (HPLC) | 342777-54-2 | 25mg | $411 | 2024-03-01 | Buy |
Cayman Chemical | 29037 | LM22B-10 | 342777-54-2 | 5mg | $93 | 2024-03-01 | Buy |
Cayman Chemical | 29037 | LM22B-10 | 342777-54-2 | 25mg | $365 | 2024-03-01 | Buy |
Cayman Chemical | 29037 | LM22B-10 | 342777-54-2 | 10mg | $166 | 2024-03-01 | Buy |
LM22B-10 Chemical Properties,Uses,Production
Uses
LM22B-10 is a TrkB and TrkC agonist. Exhibits neurotrophic activity (EC50 = 200-300 nM), improves survival and increases neurite outgrowth in hippocampal cells in vitro. Exhibits no significant activity in a screen of 57 other receptors and transporters. Inhibits binding of BDNF and neurotrophin-3 to TrkB and TrkC, respectively. Active in vivo and brain penetrant.
storage
Store at -20°C
LM22B-10 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 50)Suppliers
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---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
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Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4334 | 55 | |
Shanghai Beckham Medical Technology Co., Ltd | 021-13816613772 13816613772 | huahero21@sina.com | China | 408 | 55 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9806 | 58 |
LM22B-10
2-[[4-[[4-[BIS-(2-HYDROXYETHYL)-AMINO]-PHENYL]-(4-CHLORO-PHENYL)-METHYL]-PHENYL]-(2-HYDROXY-ETHYL)-AMINO]-ETHANOL
2,2',2',2'''-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol
Ethanol, 2,2',2'',2'''-[[(4-chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakis-
inhibit,Trk Receptor,Akt,LM-22B-10,LM22B-10,LM22B 10,Tropomyosin related kinase receptor,ERK,PKB,Inhibitor,Protein kinase B,Extracellular signal regulated kinases
2,2',2'',2'''-((((4-Chlorophenyl)methylene)bis(4,1-phenylene))bis(azanetriyl))tetrakis(ethan-1-ol)
342777-54-2