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2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID

CAS No.
287118-97-2
Chemical Name:
2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID
Synonyms
NCX 4040;NO-Aspirin;NO-ASPIRIN 2;2-(Acetyloxy)benzoic acid 4-(nitroxymethyl)phenyl ester;2-(Acetyloxy)benzoic acid 4-[(nitrooxy)methyl]phenyl ester;2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID;Benzoic acid, 2-(acetyloxy)-, 4-[(nitrooxy)methyl]phenyl ester
CBNumber:
CB9343492
Molecular Formula:
C16H13NO7
Molecular Weight:
331.28
MDL Number:
MFCD08062164
MOL File:
287118-97-2.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:02

2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Properties

Melting point 83-86°C
Boiling point 495.7±40.0 °C(Predicted)
Density 1.347±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO: soluble15mg/mL (clear solution)
form powder
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H317-H318-H400
Precautionary statements  P273-P280-P302+P352-P305+P351+P338+P310
Hazard Codes  Xi
Risk Statements  41-43
Safety Statements  26-36/37-39
RIDADR  UN 3077 9 / PGIII
WGK Germany  3

2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0414 NCX 4040 ≥98% (HPLC) 287118-97-2 5mg $110 2024-03-01 Buy
Sigma-Aldrich SML0414 NCX 4040 ≥98% (HPLC) 287118-97-2 25mg $353 2024-03-01 Buy
Tocris 4531 NCX 4040 ≥98%(HPLC) 287118-97-2 10 $173 2021-12-16 Buy
Tocris 4531 NCX 4040 ≥98%(HPLC) 287118-97-2 50 $666 2021-12-16 Buy
TRC N633005 NO-Aspirin 287118-97-2 250mg $1060 2021-12-16 Buy
Product number Packaging Price Buy
SML0414 5mg $110 Buy
SML0414 25mg $353 Buy
4531 10 $173 Buy
4531 50 $666 Buy
N633005 250mg $1060 Buy

2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Solid

Uses

A novel nitric oxide-releasing aspirin,

Biochem/physiol Actions

NCX 4040 is a nitric oxide-donating form of aspirin. NCX 4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 expression and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine expression, and appears to stabilize IkB by inhibiting proteasome function. NCX 4040 has been shown to induce apoptosis in several tumor cell lines.

2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID Suppliers

Global( 34)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 94838 76
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4428 55
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55717 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369 3477467573@qq.com China 8618 58

287118-97-2(2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID)Related Search:

NO-ASPIRIN 2 NCX 4040 2-(ACETYLOXY)-4-[(NITROOXY)METHYL]PHENYL ESTER, BENZOIC ACID NO-Aspirin 2-(Acetyloxy)benzoic acid 4-(nitroxymethyl)phenyl ester 2-(Acetyloxy)benzoic acid 4-[(nitrooxy)methyl]phenyl ester Benzoic acid, 2-(acetyloxy)-, 4-[(nitrooxy)methyl]phenyl ester 287118-97-2 Aromatics Inhibitors Intermediates & Fine Chemicals Nitric Oxide Reagents Pharmaceuticals