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Boc-Lys-OH

CAS No.
13734-28-6
Chemical Name:
Boc-Lys-OH
Synonyms
BOC-LYS;BOC-LYS-OH;BOC-L-LYSINE;BOC-LYSINE;N-ALPHA-T-BOC-L-LYSINE;NSC 343721;BOC-L-LYS-OH;Boc-Lys-OH 99%;Boc-Lys-OH,97%;BOC-L-LYSINE-OH
CBNumber:
CB9345067
Molecular Formula:
C11H22N2O4
Molecular Weight:
246.3
MDL Number:
MFCD00038203
MOL File:
13734-28-6.mol
MSDS File:
SDS
Last updated:2025-07-24 18:11:56
Product description Number Pack Size Price
Boc-Lys-OH Novabiochem? 8.53017 25g $473
Boc-Lys-OH ≥99.0% (NT) 15456 5g $231
Boc-Lys-OH ≥99.0% (NT) 15456 25g $1040
Nalpha-(tert-Butoxycarbonyl)-L-lysine >98.0%(T) B1669 5g $72
Boc-Lys-OH 99% 359688 1g $96.8
More product size

Boc-Lys-OH Properties

Melting point ~205 °C (dec.)(lit.)
alpha 22 º (c=2, CH3OH)
Boiling point 389.3°C (rough estimate)
Density 1.1313 (rough estimate)
refractive index 21.5 ° (C=2, MeOH)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Acetic Acid (Slightly), Methanol (Slightly, Sonicated), Water (Slightly, Heated,
pka 3.92±0.21(Predicted)
form Powder
color White
optical activity [α]20/D +4.6±0.5°, c = 2% in H2O
Water Solubility Soluble in water. Slightly soluble in methanol.
BRN 4252546
Sequence {Boc-Lys}
InChI InChI=1S/C11H22N2O4/c1-11(2,3)17-10(16)13-8(9(14)15)6-4-5-7-12/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m0/s1
InChIKey DQUHYEDEGRNAFO-QMMMGPOBSA-N
SMILES C(O)(=O)[C@H](CCCCN)NC(OC(C)(C)C)=O
CAS DataBase Reference 13734-28-6(CAS DataBase Reference)
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P302+P352-P362+P364
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
HS Code  2924 19 00
HazardClass  IRRITANT
NFPA 704
1
0 0

Boc-Lys-OH price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.53017 Boc-Lys-OH Novabiochem? 13734-28-6 25g $473 2025-07-31 Buy
Sigma-Aldrich 15456 Boc-Lys-OH ≥99.0% (NT) 13734-28-6 5g $231 2025-07-31 Buy
Sigma-Aldrich 15456 Boc-Lys-OH ≥99.0% (NT) 13734-28-6 25g $1040 2025-07-31 Buy
TCI Chemical B1669 Nalpha-(tert-Butoxycarbonyl)-L-lysine >98.0%(T) 13734-28-6 5g $72 2025-07-31 Buy
Sigma-Aldrich 359688 Boc-Lys-OH 99% 13734-28-6 1g $96.8 2025-07-31 Buy
Product number Packaging Price Buy
8.53017 25g $473 Buy
15456 5g $231 Buy
15456 25g $1040 Buy
B1669 5g $72 Buy
359688 1g $96.8 Buy

Boc-Lys-OH Chemical Properties,Uses,Production

Chemical Properties

white to off-white powder

Uses

Boc-Lys-OH (Nα-Boc-L-lysine) can be used as a building block to synthesize:
A heterotrifunctional peptide-based linker molecule applicable as a bio-labeling reagent.
Lysine derivatives of azamacrocycle and anthraquinone.
Boc-Lys(Bn4-DTPA)-OH, a precursor to synthesize diethylene triamine pentaacetic acid (DTPA) containing peptides.
A ferrocene-amino acid conjugate which is used in developing chemical warfare agent (CWA) sensor.

Uses

N-Boc-L-lysine is a protected analogue of a major amino acid participating in the binding of AcH to proteins. N-Boc-L-lysine as well as other t-butoxycarbonyl (Boc) amino acids can be converted to their respective amino acids via cleavage of the urethane bond.

Production Methods

L-lysine was added to acetone and Et3N under stirring at 25 °C. After that, di-tert-butyl dicarbonate was added. After 4.5 h, decompression evaporates acetone, and the water layer is extracted with ethyl ether 3 times. The dilute HC1 was added to the aqueous layer to adjust pH 2-3. The crude product was purified to obtain Boc-Lys-OH.
N-alpha-(tert-Butoxycarbonyl)-L-lysine

reaction suitability

Boc solid-phase peptide synthesis

References

[1] Patent: CN102993200, 2016, B. Location in patent: Paragraph 0050; 0051; 0052
[2] Journal of Materials Chemistry B, 2014, vol. 2, # 42, p. 7351 - 7359
[3] Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1995, vol. 34, # 1, p. 45 - 47
[4] Chinese Chemical Letters, 2012, vol. 23, # 3, p. 297 - 300
[5] Patent: CN103833623, 2016, B. Location in patent: Paragraph 0058; 0059; 0062

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View Lastest Price from Boc-Lys-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-Lys-OH pictures 2025-11-10 Boc-Lys-OH
13734-28-6
US $0.00 / Kg/Drum 1KG 98%min 1000kgs WUHAN FORTUNA CHEMICAL CO., LTD
Boc-L-Lys-OH pictures 2025-11-10 Boc-L-Lys-OH
13734-28-6
US $0.00-0.00 / kg 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
N-alpha-(tert-Butoxycarbonyl)-L-lysine pictures 2025-11-10 N-alpha-(tert-Butoxycarbonyl)-L-lysine
13734-28-6
US $10.00 / KG 1KG 99% 5tons Hebei Chuanghai Biotechnology Co., Ltd
  • Boc-Lys-OH pictures
  • Boc-Lys-OH
    13734-28-6
  • US $0.00 / Kg/Drum
  • 98%min
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • Boc-L-Lys-OH pictures
  • Boc-L-Lys-OH
    13734-28-6
  • US $0.00-0.00 / kg
  • 98%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
n-Boc-L-lysine Boc-Lys-OH >=99.0% (NT) Boc-Lys-OH 99% (2S)-6-amino-2-(tert-butoxycarbonylamino)hexanoic acid (2S)-6-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid (S)-2-[(tert-Butyloxycarbonyl)amino]-6-aminohexanoic acid N2-(tert-Butoxycarbonyl)lysine N2-(tert-Butyloxycarbonyl)-L-lysine Nα-(tert-Butyloxycarbonyl)-L-lysine N-alpha-tert-Butoxycarbonyl-L-lysine,98% Nalpha-BOC-L-Lysine,99% N-Boc-L-lysine ,98% N~6~-(tert-butoxycarbonyl)-L-lysine BOC-L-LYSINE-OH BOC-L-LYS-OH N-ALPHA-BOC-L-LYSINE N-ALPHA-T-BUTOXYCARBONYL-L-LYSINE N-ALPHA-TERT-BUTYLOXYCARBONYL-L-LYSINE NALPHA-(TERT-BUTOXYCARBONYL)-L-LYSINE (S)-6-AMino-2-(tert-butoxycarbonylaMino)hexanoic Acid N2-Carboxy-L-lysine N2-tert-Butyl Ester NSC 343721 α-tert-Butoxycarbonyl-L-lysine Nalpha-Boc-L-lysine Boc-Lys-OH N^a-Boc-L-lysine, 97% (2S)-6-amino-2-[(tert-butoxy-oxomethyl)amino]hexanoic acid (2S)-6-ammonio-2-(tert-butoxycarbonylamino)hexanoate (2S)-6-ammonio-2-[(tert-butoxy-oxomethyl)amino]hexanoate (2S)-6-azaniumyl-2-(tert-butoxycarbonylamino)hexanoate (2S)-6-azaniumyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoate Nα-(tert-Butoxycarbonyl)-L-lysine N2-[(1,1-dimethylethoxy)carbonyl]-L-lysine N-tert-Butoxycarbonyl-L-lysine N-α-Boc-L-lysine NA-T-BOC-L-LYSINE NALPHA-BOC-1-LYSINE N-ALPHA-T-BUTYLOXYCARBONYL-L-LYSINE Boc -L-Lysine α-(tert-Butoxycarbonyl)-L-Lysine BOC-L-LEUCYL PROLINE N-TERT-BUTOXYCARBONYL LYSINE Nα-Boc-L-lysine, Nα-(tert-Butoxycarbonyl)-L-lysine L-Lysine, N(2)-[(1,1-dimethylethoxy)carbonyl]- Nα-(tert-Butoxycarbonyl)-L-lysine ,98% N-a-(tert.-butoxycarbonyl)-L-lysine (Tert-Butoxy)Carbonyl Lys-OH (2S)-6-ammonio-2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]hexanoate Nα-(tert-Butoxycarbonyl)-L-lysine > N-alpha-(tert-Butoxycarbonyl)-L-lysine USP/EP/BP Nα-(tert-Butoxycarbonyl)-L-lysine Nα-Boc-L-lysine N2-Boc-L-lysine N-alpha-Acetyl-N&epsilon Nα-Boc-L-lysine BOC-L-LYSINE BOC-LYSINE BOC-LYS-OH N-ALPHA-T-BOC-L-LYSINE BOC-LYS