ChemicalBook >> CAS DataBase List >>Protopine
Protopine
- CAS No.
- 130-86-9
- Chemical Name:
- Protopine
- Synonyms
- BIFLORIN;Protopin;PROTOPINE;Biflorine;Corydinine;Tangeratin;Hypercorine;AKOS 243-72;Corydalis C;Protopine USP/EP/BP
- CBNumber:
- CB9347526
- Molecular Formula:
- C20H19NO5
- Molecular Weight:
- 353.37
- MDL Number:
- MFCD00022322
- MOL File:
- 130-86-9.mol
- MSDS File:
- SDS
Last updated:2023-07-12 16:34:12
| Melting point | 203-205?C |
|---|---|
| Boiling point | 486.8°C (rough estimate) |
| Density | 1.399 (calc) |
| refractive index | 1.5800 (estimate) |
| storage temp. | Inert atmosphere,2-8°C |
| Water Solubility | Insoluble in water |
| solubility | DMSO : 12.5 mg/mL (35.37 mM; Need ultrasonic) |
| pka | 7.86±0.20(Predicted) |
| form | powder to crystal |
| color | White to Light gray to Light yellow |
| LogP | 3.760 (est) |
| EWG's Food Scores | 1 |
| FDA UNII | UIW569HT35 |
| NIST Chemistry Reference | Protopine(130-86-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312+P330-P501 | |||||||||
| Safety Statements | 24/25 | |||||||||
| RIDADR | 1544 | |||||||||
| RTECS | VS2800000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29391900 | |||||||||
| Toxicity | guinea pig,LD50,intraperitoneal,116mg/kg (116mg/kg),Therapie. Vol. 28, Pg. 767, 1973. | |||||||||
| NFPA 704 |
|
Protopine price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL89546 | Protopine phyproof? Reference Substance | 130-86-9 | 10mg | $425 | 2024-03-01 | Buy |
| TCI Chemical | P2611 | Protopine >98.0%(GC) | 130-86-9 | 5mg | $45 | 2024-03-01 | Buy |
| TCI Chemical | P2611 | Protopine >98.0%(GC) | 130-86-9 | 25mg | $130 | 2024-03-01 | Buy |
| TCI Chemical | P2611 | Protopine >98.0%(GC) | 130-86-9 | 100mg | $355 | 2024-03-01 | Buy |
| Usbiological | 300834 | Protopine | 130-86-9 | 20mg | $320 | 2021-12-16 | Buy |
Protopine Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Protopine is a Ca2+ channel blocker and antiplatelet agent. Immunomodulator
Definition
ChEBI: A dibenzazecine alkaloid isolated from Fumaria vaillantii.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Purification Methods
It crystallises from EtOH/CHCl3. The picrate has m ~240o(dec). [Beilstein 27 H 558, 17 I 568, 17 II 620, 17 III/IV 6881.]
Protopine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 183)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | marketing1@neostarunited.com | China | 8349 | 58 |
View Lastest Price from Protopine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-24 | Protopine
130-86-9
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2023-02-13 | Protopine
130-86-9
|
US $90.00 / KG | 1KG | 99% | 100mt | Hebei baicao biology science and technology co., ltd | |
 |
2020-02-11 | Protopine
130-86-9
|
US $9.80 / KG | 1g | ＞98% | 20 tons | Career Henan Chemical Co |
130-86-9(Protopine)Related Search:
1of4
7,13a-Secoberbin-13a-one, 7-methyl-2,3:9,10-bis(methylenedioxy)-
7-Methyl-6,8,9,16-tetrahydrodi[1,3]benzodioxolo[4,5-c:5,6-g]azecin-15(7H)-one
Biflorine
Bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)-one, 4,6,7,14-tetrahydro-5-methyl-
Corydinine
Hypercorine
Protopin
BIFLORIN
AKOS 243-72
5,7-DIHYDROXY-2-METHYLCHROMONE-6-C-BETA-D-GLUCOPYRANOSIDE
PROTOPINE
4,6,7,14-Tetrahydro-5-methyl-bis[1,3]benzodioxolo[4,5-c-5',6'-g] azecin-13(5H)-one
7-Methyl-2,3:9,10-bis(methylenedioxy)-7,13a-secoberbin-13a-one
5-Methyl-9,10-(methylenedioxy)-4,6,7,13-tetrahydrobenzo[e]-1,3-dioxolo[4,5-l][2]benzazecine-12(5H)-one
6-Methyl-3,4-(methylenebisoxy)-10,11-(methylenebisoxy)-5,6,7,8-tetrahydrodibenzo[c,g]azecine-13(14H)-one
7-Methyl-6,7,8,9-tetrahydro-[1,3]dioxolo[4',5':5,6]benzo[1,2-c][1,3]dioxolo[5',4':4,5]benzo[1,2-g]azecin-15(16H)-one
4,6,7,14-Tetrahydro-5-Methyl-
Tangeratin
Corydalis C
Protopine (Corydinine)
Protopine, 98%, from Corydalis yanhusuo W. T. Wang ex Z. Y. Su et C. Y. Wu
Protopine USP/EP/BP
1H-Isoindole-1,3(2H)-dione,2-(3-butyn-2-yl)-
130-86-9
C20H19O5
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract
Aromatics
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals