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ChemicalBook >> CAS DataBase List >>N-[1-[(1S)-3-(dimethylamino)-1-phenylpropyl]pyrazol-4-yl]-6,6-dimethyl-1,4,5,7-tetrahydroindazole-3-carboxamide

N-[1-[(1S)-3-(dimethylamino)-1-phenylpropyl]pyrazol-4-yl]-6,6-dimethyl-1,4,5,7-tetrahydroindazole-3-carboxamide

N-[1-[(1S)-3-(dimethylamino)-1-phenylpropyl]pyrazol-4-yl]-6,6-dimethyl-1,4,5,7-tetrahydroindazole-3-carboxamide Structure
N-[1-[(1S)-3-(dimethylamino)-1-phenylpropyl]pyrazol-4-yl]-6,6-dimethyl-1,4,5,7-tetrahydroindazole-3-carboxamide structure
CAS No.
1557232-32-2
Chemical Name:
N-[1-[(1S)-3-(dimethylamino)-1-phenylpropyl]pyrazol-4-yl]-6,6-dimethyl-1,4,5,7-tetrahydroindazole-3-carboxamide
Synonyms
GNE-9822;N-[1-[(1S)-3-(dimethylamino)-1-phenylpropyl]pyrazol-4-yl]-6,6-dimethyl-1,4,5,7-tetrahydroindazole-3-carboxamide;1H-Indazole-3-carboxamide, N-[1-[(1S)-3-(dimethylamino)-1-phenylpropyl]-1H-pyrazol-4-yl]-4,5,6,7-tetrahydro-6,6-dimethyl-
CBNumber:
CB93488099
Molecular Formula:
C24H32N6O
Molecular Weight:
420.55
MDL Number:
MFCD28386193
MOL File:
1557232-32-2.mol
Last updated:2023-03-31 09:12:58
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N-[1-[(1S)-3-(dimethylamino)-1-phenylpropyl]pyrazol-4-yl]-6,6-dimethyl-1,4,5,7-tetrahydroindazole-3-carboxamide Chemical Properties,Uses,Production

Description

GNE-9822 is a potent and selective ITK inhibitor. GNE-9822 shows good ADME properties in preclinical species. Interleukin-2 inducible T-cell kinase (ITK), a member of the Tec family of tyrosine kinases, plays a major role in T-cell signaling downstream of the T-cell receptor (TCR), and considerable efforts have been directed toward discovery of ITK-selective inhibitors as potential treatments of inflammatory disorders such as asthma.

N-[1-[(1S)-3-(dimethylamino)-1-phenylpropyl]pyrazol-4-yl]-6,6-dimethyl-1,4,5,7-tetrahydroindazole-3-carboxamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-[1-[(1S)-3-(dimethylamino)-1-phenylpropyl]pyrazol-4-yl]-6,6-dimethyl-1,4,5,7-tetrahydroindazole-3-carboxamide Suppliers

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TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
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TargetMol Chemicals Inc. 		58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
Shanghai Lollane Biological Technology Co.,Ltd. 55
Shanghai EFE Biological Technology Co., Ltd. 58
ShangHai Biochempartner Co.,Ltd 62
TargetMol Chemicals Inc. 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 58
Wuhan Jingkangen Biomedical Technology Co., Ltd 58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd 58
N-[1-[(1S)-3-(dimethylamino)-1-phenylpropyl]pyrazol-4-yl]-6,6-dimethyl-1,4,5,7-tetrahydroindazole-3-carboxamide GNE-9822 1H-Indazole-3-carboxamide, N-[1-[(1S)-3-(dimethylamino)-1-phenylpropyl]-1H-pyrazol-4-yl]-4,5,6,7-tetrahydro-6,6-dimethyl- 1557232-32-2