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Neuraminidase

CAS No.
9001-67-6
Chemical Name:
Neuraminidase
Synonyms
SIALIDASE;EC 3.2.1.18;SIALIDASE L;IUB: 3.2.1.18;ALP Separator;NEURAMINIDASE;Neuraminidase B;Neuraminidase A;exo-α-sialidase;SIALIDASE TYPE V
CBNumber:
CB9348886
Molecular Formula:
NULL
Molecular Weight:
0
MDL Number:
MFCD00131711
MOL File:
Mol file
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

Neuraminidase Properties

Density 1.00 g/mL at 20 °C
storage temp. 2-8°C
form lyophilized powder
color white
Water Solubility Soluble in water or 10mM phosphate buffer, pH 6.0
EWG's Food Scores 1
EPA Substance Registry System Neuraminidase (9001-67-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Warning
Hazard statements  H290-H315-H319-H335
Precautionary statements  P234-P261-P264-P271-P302+P352-P305+P351+P338
Safety Statements  22-24/25
RIDADR  UN3373 - class 6.2 Biological substance, Category B
WGK Germany  3
RTECS  QQ3450000
3-10
TSCA  Yes

Neuraminidase price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N7885 Neuraminidase from Vibrio cholerae Type III, buffered aqueous solution, 0.2 μm filtered, 1-5?units/mg protein (Lowry, using NAN-lactose) 9001-67-6 1unit $181 2024-03-01 Buy
Sigma-Aldrich N8271 α(2→3,6,8,9) Neuraminidase from Arthrobacter ureafaciens recombinant, expressed in E. coli, buffered aqueous solution 9001-67-6 0.2unit $638 2024-03-01 Buy
Sigma-Aldrich N7885 Neuraminidase from Vibrio cholerae Type III, buffered aqueous solution, 0.2 μm filtered, 1-5?units/mg protein (Lowry, using NAN-lactose) 9001-67-6 2units $332 2024-03-01 Buy
Sigma-Aldrich N5631 Neuraminidase from Clostridium perfringens (C. welchii) Type VIII, lyophilized powder, 10-20?units/mg protein (using 4MU-NANA), 3.5-8.0?units/mg protein (mucin) 9001-67-6 1unit $69.2 2024-03-01 Buy
Sigma-Aldrich N5631 Neuraminidase from Clostridium perfringens (C. welchii) Type VIII, lyophilized powder, 10-20?units/mg protein (using 4MU-NANA), 3.5-8.0?units/mg protein (mucin) 9001-67-6 5units $226 2024-03-01 Buy
Product number Packaging Price Buy
N7885 1unit $181 Buy
N8271 0.2unit $638 Buy
N7885 2units $332 Buy
N5631 1unit $69.2 Buy
N5631 5units $226 Buy

Neuraminidase Chemical Properties,Uses,Production

Uses

Neuraminidase is used as a hydrolytic enzyme that removes sialic acid from mucoproteins, used in a study to assess binding with human T lymphocytes in sheep pretreated with neuraminidase. It has also been used in a study to investigate the effect of bile salts on the action of hydrolysis by neuraminidase.

Uses

Neuraminidase is an important deglycosylation enzyme capable of cleaving all non-reducing unbranched N-acetylneuraminic and N-glycolylneuraminic acid residues by hydrolysis of α(2→6), α(2→3), α(2→8), and α(2→9) linkages (affinity in the order given). Branched sialic acids may also be cleaved with the use of high concentrations of enzyme and prolonged incubations. Desialylated glycoproteins may then be further characterized by treatment with various exoglycosidases resulting in partial or complete O-deglycosylation. SDS-PAGE and MALDI-TOF MS are typically utilized in purification, structural analysis, and sequencing process. These techniques also remove heterogeneity and charge from the glycoprotein.

Uses

Neuraminidase from Vibrio cholera has been used in a study to describe a five-step purification method. It has also been used in a study to investigate modification of leukemia L1210 tumor cells.

General Description

Neuraminidase enzymes are glycoside hydrolase enzymes that catalyze hydrolysis of terminal sialic acid residues. The most well-known are the viral nearamidases, which promote influenza virus release.

Biochem/physiol Actions

Vibrio cholerae neuraminidase has been shown to promote cholera toxin infection by binding the toxin and aiding in its uptake by cells.

Neuraminidase Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 126)Suppliers
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Shanghai Zheyan Biotech Co., Ltd.
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View Lastest Price from Neuraminidase manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
neuraminidase pictures 2023-08-03 neuraminidase
9001-67-6
US $42.00-38.80 / KU 10KU ≥400U/mg 1000ku Hubei Xindesheng Material Technology Co., Ltd.
ACETYLNEURAMINYL HYDROLASE pictures 2020-01-08 ACETYLNEURAMINYL HYDROLASE
9001-67-6
US $2.00 / KG 1KG 99 100kg Career Henan Chemical Co
  • neuraminidase pictures
  • neuraminidase
    9001-67-6
  • US $42.00-38.80 / KU
  • ≥400U/mg
  • Hubei Xindesheng Material Technology Co., Ltd.
EC 3.2.1.18 EC 3.2.1.18 TYPE II EC 3.2.1.18 TYPE III EC 3.2.1.18 TYPE V EC 3.2.1.18 TYPE VI EC 3.2.1.18 TYPE VI-A EC 3.2.1.18 TYPE VIII EC 3.2.1.18 TYPE X IUB: 3.2.1.18 ACYLNEURAMINYL HYDROLASE ACYLNEURAMINYL HYDROLASE TYPE II ACYLNEURAMINYL HYDROLASE TYPE III ACYLNEURAMINYL HYDROLASE TYPE V ACYLNEURAMINYL HYDROLASE TYPE VI ACYLNEURAMINYL HYDROLASE TYPE VI-A ACYLNEURAMINYL HYDROLASE TYPE VIII ACYLNEURAMINYL HYDROLASE TYPE X ACYLNEURAMYL HYDROLASE ACETYLNEURAMINYL HYDROLASE ACETYLNEURAMINYL HYDROLASE AGAROSE ALPHA2,3-NEURAMINIDASE ALPHA2,3-NEURAMINIDASE, MACROBDELLA DECORA ALPHA2-3,6,8,9-NEURAMINIDASE a2,3-Neuraminidase, Macrobdella decora, Recomb. a2,3-Neuraminidase, Streptococcus pneumoniae a2-3,6,8,9-Neuraminidase, Arthrobacter ureafaciens, Recomb. a2-3,6,8,9-Neuraminidase, Recomb., E. coli a2-3,6,8-Neuraminidase, Clostridium perfringens a2-3,6,8-Neuraminidase, Vibriocholerae Neuraminidase Clostridium perfringens (C.elchii) neuraminidase from arthrobacter*ureafaciens neuraminidase from clostridium perfrin-gens neuraminidase from newcastle*disease virus neuraminidase from vibrio cholerae Neuraminidase solution from Vibrio cholerae neuraminidase type vi from clostridium*perfringen neuraminidase type X from*clostridium perfringens NEURAMINIDASE FROM VIBRIO CHOLERAE, ~2 U /ML NEURAMINIDASE TYPE II FROM VIBRIO*CHOLER AE A-2(3,6,8,9)-NEURAMINIDASE, EXPRESSED*IN E. COLI NEURAMINIDASE FROM CLOSTRIDIUM PERFRIN-& A-2(3,6)-NEURAMINIDASE, RECOMBINANT*EXPR ESSED IN E. NEURAMINIDASE FROM STREPTOCOCCUS SP. NEURAMINIDASE TYPE VI FROM CLOSTRIDIUM*P ERFRINGENS NEURAMINIDASE, WIDE SPECTRUM, PROTEOMICS NEURAMINIDASE TYPE III FROM VIBRIO*CHOLE RAE NEURAMINIDASE FROM SALMONELLA & NEURAMINIDASE F. CLOSTRIDIUM PERFRINGENS , >4 U/VIAL, 25 UG* A-2,3-NEURAMINIDASE, RECOMBINANT,*EXPRES SED IN E. C A(2-->3 6 8 9) NEURAMINIDASE FROM & NEURAMINIDASE FROM CLOSTRIDIUM PERFRIN-G ENS, ~1 U/MG NEURAMINIDASE TYPE V FROM CLOSTRIDIUM*PE RFRINGENS NEURAMINIDASE TYPE VIII FROM*CLOSTRIDIUM PERFRINGEN NeuraminidaseExVibrioComa(Cholerae) neuraminidase from clostridium perfringens (c. welchii) α(2→3) neuraminidase from streptococcus pneumoniae alpha-neuraminidase ALP Separator