ChemicalBook >> CAS DataBase List >>Taurodeoxycholic acid sodium salt
Taurodeoxycholic acid sodium salt
- CAS No.
- 1180-95-6
- Chemical Name:
- Taurodeoxycholic acid sodium salt
- Synonyms
- SODIUM TAURODEOXYCHOLATE;Taurodeoxycholate sodium salt;Taurodeoxycholic acid sodium salt hydrate;5B2;12B1;sodium 2-[[(3B1;sodium taurodeoxylate;SodiuM taurodeoxycholat;Sodium deoxytaurocholate;Taurodeoxycholate sodium
- CBNumber:
- CB9349065
- Molecular Formula:
- C26H44NNaO6S
- Molecular Weight:
- 521.69
- MDL Number:
- MFCD00003671
- MOL File:
- 1180-95-6.mol
Last updated:2025-10-27 10:42:20
| Product description | Number | Pack Size | Price |
| Taurodeoxycholic Acid, Sodium Salt - CAS 1180-95-6 - Calbiochem Detergentusefulforthesolubilizationoflipidsandmembrane-boundproteins.A | 580221 | 5G | $211 |
| Taurodeoxycholic Acid, Sodium Salt - CAS 1180-95-6 - Calbiochem Detergentusefulforthesolubilizationoflipidsandmembrane-boundproteins.A | 580221 | 50g | $807 |
| Taurodeoxycholic Acid (sodium salt) ≥95% | 15935 | 1g | $35 |
| Taurodeoxycholic Acid (sodium salt) ≥95% | 15935 | 5g | $88 |
| Taurodeoxycholic Acid (sodium salt) ≥95% | 15935 | 25g | $350 |
| More product size | |||
| Melting point | 168 °C (dec.)(lit.) |
|---|---|
| alpha | 33 º (c=3, water) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | H2O: 0.5 M at 20 °C, clear, colorless to faintly yellow |
| form | Solid |
| pka | 1.9 |
| color | White to Off-White |
| Water Solubility | soluble |
| InChIKey | YXHRQQJFKOHLAP-UROAIUCXNA-M |
| CAS DataBase Reference | 1180-95-6(CAS DataBase Reference) |
| FDA UNII | 5PE424S83L |
| UNSPSC Code | 41141802 |
| NACRES | NB.34 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H335-H319 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
| Hazard Codes | Xi |
| Risk Statements | 37 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| F | 3-10 |
| HS Code | 29242990 |
Taurodeoxycholic acid sodium salt price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 580221 | Taurodeoxycholic Acid, Sodium Salt - CAS 1180-95-6 - Calbiochem Detergentusefulforthesolubilizationoflipidsandmembrane-boundproteins.A | 1180-95-6 | 5G | $211 | 2025-07-31 | Buy |
| Sigma-Aldrich | 580221 | Taurodeoxycholic Acid, Sodium Salt - CAS 1180-95-6 - Calbiochem Detergentusefulforthesolubilizationoflipidsandmembrane-boundproteins.A | 1180-95-6 | 50g | $807 | 2025-07-31 | Buy |
| Cayman Chemical | 15935 | Taurodeoxycholic Acid (sodium salt) ≥95% | 1180-95-6 | 1g | $35 | 2021-12-16 | Buy |
| Cayman Chemical | 15935 | Taurodeoxycholic Acid (sodium salt) ≥95% | 1180-95-6 | 5g | $88 | 2021-12-16 | Buy |
| Cayman Chemical | 15935 | Taurodeoxycholic Acid (sodium salt) ≥95% | 1180-95-6 | 25g | $350 | 2021-12-16 | Buy |
Taurodeoxycholic acid sodium salt Chemical Properties,Uses,Production
Chemical Properties
white to almost white crystalline powder
Uses
Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.
in vivo
Taurodeoxycholate (1.25-5 mg/kg, p.o., 6 days) sodium salt ameliorates dextran sodium sulfate (DSS)-induced colitis in mice[9].
Taurodeoxycholate sodium salt (Taurodeoxycholic acid form, 50 mg/kg; i.p.; once daliy for 34 d) prevents neuropathology and associated behavioral deficits in the 3-nitropropionic acid rat model of Huntington's disease (HD) [10].
Taurodeoxycholate sodium salt (Taurodeoxycholic acid form, 500 mg/kg; s.c.; once every 3 d for 7 weeks) leads to a significant reduction in striatal neuropathology of the R6/2 transgenic HD mouse[11].
Taurodeoxycholate (0.5 mg/kg; i.v., once) sodium salt confers protection to C57BL/6N mice with sepsis, but does not protect TGR5 KO mice under sepsis[12].
| Animal Model: | A mouse colitis model (fed with 3% (w/v) DSS in drinking water for the first seven days and then switched to normal drinking water for an additional two days)[9] |
| Dosage: | 1.25, 2.5, and 5 mg/kg |
| Administration: | Oral gavage (p.o.), from day 3 to day 8, once a day |
| Result: | Prevented loss of body weight, shortening of the colon, production of pro-inflammatory cytokines, infiltration of pro-inflammatory cells, and mucosal ulceration in the colon. |
| Animal Model: | Huntington's disease model in mouse[10] |
| Dosage: | 50 mg/kg |
| Administration: | Intraperitoneal injection; once daliy for 34 d, injected 3-NP at 6 hr after Taurodeoxycholic acid treatment |
| Result: | Reduced striatal atrophy, decreased striatal apoptosis, as well as fewer and smaller size ubiquitinated neuronal intranuclear huntingtin inclusions. Significantly improved locomotor and sensorimotor deficits. |
| Animal Model: | C57BL/6N mice, Lipopolysaccharides (HY-D1056) injection model of sepsis[12] |
| Dosage: | 0.5 mg/kg |
| Administration: | Intravenous injection, 30 min or 24 h after LPS injection |
| Result: | Improved the survival rate of mice with sepsis. Decreased liver and kidney damage in septic mice. Ameliorated systemic inflammation and normalized blood pressure in septic mice. |
Purification Methods
The Na salt is dissolved in the smallest volume of H2O, a saturated solution of aqueous NaCl/Et2O is added and the mixture is stored at 0o for 24hours. Then shake the mixture well, keep it in the cold for another day and filter the crystals with gentle shaking, wash them with ice-cold saturated aqueous NaCl saturated with Et2O, dry them over CaCl2 and extract them with absolute EtOH. Add ~10mL of H2O to the solid followed by enough Et2O to incipient cloudiness. Store it overnight at 0o. Add ice-cold Et2O to make 250mL, collect the crystals, wash them with Et2O then pet ether and dry them in air. The purification can be repeated with NaCl and Et2O with ~85% recovery. NB: precipitation will not occur unless enough H2O is present. Its solubility in H2O is 10%. [Cortese J Am Chem Soc 59 2532 1937.] The free acid has m 141-144o. [Norman Ark Kemi 8 331 1956.] It forms mixed micelles and solubilises some membrane proteins [Hajjar et al. J Biol Chem 2 5 8 192 1983]. [Beilstein 10 IV 1611.]
Taurodeoxycholic acid sodium salt Preparation Products And Raw materials
Global( 322)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Sichuan Zhuoyu Yantang Technology Co., Ltd. | +8613288715578 | sales@sichuanzyyt.com | China | 12223 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Anhuyan (Hainan) Biotechnology Co., LTD | +86-18163349544; +8618163349544 | mollylucking@foxmail.com | China | 3000 | 58 |
| Shaanxi Xianhe Biotech Co., Ltd | +86-17709210191; +8617709210191 | Jerry@xhobio.com | China | 883 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13505 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21616 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
Related articles
- Taurodeoxycholic Acid Sodium Salt: Chaperoning Activity & In Vivo Toxicity
- Taurodeoxycholic acid sodium salt (TDCA) acts as a chemical chaperone, has low systemic toxicity, but causes injection-site le....
- Oct 27，2025
View Lastest Price from Taurodeoxycholic acid sodium salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-10 | Taurodeoxycholic acid sodium salt
1180-95-6
|
US $2.00 / g | 1g | 99.99 | 10000 | Anhuyan (Hainan) Biotechnology Co., LTD | |
 |
2025-11-07 | Taurodeoxycholic acid sodium salt
1180-95-6
|
US $0.00 / KG | 1KG | 97%min | 2000KGS | HANGZHOU HAILAN CHEMICAL CO.,LTD. | |
 |
2025-11-04 | Sodium taurodeoxycholate
1180-95-6
|
US $0.00 / KG | 1KG | 0.99 | 1000KG | Shaanxi Xianhe Biotech Co., Ltd |
-
- Taurodeoxycholic acid sodium salt
1180-95-6
- US $2.00 / g
- 99.99
- Anhuyan (Hainan) Biotechnology Co., LTD
-
- Taurodeoxycholic acid sodium salt
1180-95-6
- US $0.00 / KG
- 97%min
- HANGZHOU HAILAN CHEMICAL CO.,LTD.
-
- Sodium taurodeoxycholate
1180-95-6
- US $0.00 / KG
- 0.99
- Shaanxi Xianhe Biotech Co., Ltd
1180-95-6(Taurodeoxycholic acid sodium salt)Related Search:
Taurine
2-aminoethanesulphonamide monohydrochloride
GLYCOCHOLIC ACID SODIUM SALT
Tauroursodeoxycholate
Sodium deoxycholate
TAUROCHOLIC ACID SODIUM SALT HYDRATE
Tauroursodeoxycholic acid
TAUROURSODEOXYCHOLIC ACID SODIUM SALT
TAUROCHENODEOXYCHOLIC ACID SODIUM SALT
Sodium taurodeoxycholate hydrate
1of4
TAURODEOXYCHOLIC ACID SODIUM
TAURODEOXYCHOLIC ACID SODIUM SALT
SODIUM TAURODEOXYCHOLATE SODIUM SALT
SODIUM TAURODESOXYCHOLATE SODIUM SALT
2-[(3ALPHA,12ALPHA-DIHYDROXY-24-OXO-5BETA-CHOLAN-24-YL)-AMINO] ETHANESULFONIC ACID SODIUM SALT
5BETA-CHOLANIC ACID-3ALPHA,12ALPHA-DIOL 24-N-(2-SULFOETHYL)-AMIDE SODIUM
5-BETA-CHOLANIC ACID-3-ALPHA, 12-ALPHA-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT
3ALPHA,12ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE SODIUM SALT
sodium 2-[[(3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate
Ethanesulfonic acid, 2-(3.alpha.,5.beta.,12.alpha.)-3,12-dihydroxy-24-oxocholan-24-ylamino-, monosodium salt
sodium taurodeoxylate
Sodium 2-[[(3a,5b,12a)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate
Cholane, ethanesulfonic acid deriv.
Sodium deoxytaurocholate
Sodium taurodesoxycholate
Taurodeoxycholate sodium
Taurodeoxycholic acid sodium salt hydrate,97%
2-[(3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid sodium salt
2-[(3α,12α-Dihydroxy-24-oxo-5β-cholane)-24-ylamino]ethanesulfonic acid sodium salt
3α,12α-Dihydroxy-24-[[2-(sodiooxysulfonyl)ethyl]amino]-5β-cholane-24-one
N-(3α,12α-Dihydroxy-24-oxo-5β-cholane-24-yl)taurine sodium salt
N-[2-(Sodiooxysulfonyl)ethyl]-3α,12α-dihydroxy-5β-cholane-24-oic amide
Sodium tarurodeoxycholate
2-(3α,6α-Dihydroxy-24-oxo-5β-cholan-24-ylamino)ethanesulfonic acid sodium salt
Sodium Taurodeoxycholic acid
Taurodeoxycholic acid sodium salt ,97%
Taurodeoxychloic Acid SodiuM Salt
SodiuM taurodeoxycholat
N-(3α,12α-Dihydroxy-5β-cholan-24-oyl)-taurine MonosodiuM Salt
SodiuM 3α,12α-Dihydroxy-5β-cholanoyltaurate
SODIUM TAUROUSODEOXYCHOLATE
Ursodeoxycholic Impurity 16
sodium 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate
Ethanesulfonic Acid,2-[[(3A,5B,12A-3,12-Dihydroxy-24-OxocholaN-24-Yl]Amino]-, Monosodium Salt
Sodium 2-((R)-4-((3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonate
Taurodeoxycholic acid sodium saltr
Taurodeoxycholic acid sodium salt ISO 9001：2015 REACH
Taurodeoxycholicacid (Crude)
sodium 2-[[(3α,5β,12α)-3,12-dihydroxy-24-o...
Sodium taurodeoxycholate, hydrate, ≥95% (HPLC)
)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate
12B1
5B2
sodium 2-[[(3B1
Sodium Taurodeoxycholate Dried (STDC Dried) extrapure, 97%
Taurodeoxycholic acid sodium salt hydrate
SODIUM TAURODEOXYCHOLATE
Taurodeoxycholate sodium salt
Urosodeoxycholic Acid Impurity 16
5β-CHOLANIC ACID-3α, 12α-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT
Sodium taurine deoxycholate
Taurodeoxycholate sodium salt, 10 mM in DMSO
Taurodeoxycholic Acid Sodium Salt (Sodium Taurodeoxycholate)
TAURODEOXYCHOLIC ACID SODIUM SALT-2,2,4,4-d4 ACID
1180-95-6
C26H44NNaO6SxH2O
C26H44NO6S種a
Anionic
