5-FORMYL-2-THIOPHENECARBOXYLIC ACID
- CAS No.
- 4565-31-5
- Chemical Name:
- 5-FORMYL-2-THIOPHENECARBOXYLIC ACID
- Synonyms
- AKOS MSC-0225;AURORA KA-6755;5-FORMYLTHENOIC ACID;5-formyl-2-thiophenecarboxylate;2-Formyl-5-thiophenecarboxylic acid;5-FORMYL-2-THIOPHENECARBOXYLIC ACID;5-FORMYL-THIOPHEN-2-CARBOXYLIC ACID;5-Carboxy-2-thiophenecarboxaldehyde;5-FORMYL-THIOPHENE-2-CARBOXYLIC ACID;5-Formyl-2-thiophenecarboxylicAcid>
- CBNumber:
- CB9349393
- Molecular Formula:
- C6H4O3S
- Molecular Weight:
- 156.16
- MDL Number:
- MFCD00191437
- MOL File:
- 4565-31-5.mol
| Product description | Number | Pack Size | Price |
| 5-Formyl-2-thiophenecarboxylic Acid >98.0%(GC)(T) | F0336 | 1g | $85 |
| 5-Formyl-2-thiophenecarboxylic Acid >98.0%(GC)(T) | F0336 | 5g | $215 |
| 5-FormylthenoicAcid | F701050 | 25mg | $125 |
| 5-Formylthiophene-2-carboxylic acid | 6H21-1-X0 | 1g | $93 |
| 5-Formyl-2-thiophenecarboxylic Acid 98% | JK424250 | 1g | $129 |
| More product size | |||
| Melting point | 169 °C |
|---|---|
| Boiling point | 371.4±27.0 °C(Predicted) |
| Density | 1.514±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 3.05±0.10(Predicted) |
| color | Light yellow to Brown |
| InChI | InChI=1S/C6H4O3S/c7-3-4-1-2-5(10-4)6(8)9/h1-3H,(H,8,9) |
| InChIKey | VFEAMMGYJFFXKV-UHFFFAOYSA-N |
| SMILES | C1(C(O)=O)SC(C=O)=CC=1 |
| CAS DataBase Reference | 4565-31-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P271-P280 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-36 | |||||||||
| Safety Statements | 26-36 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29349990 | |||||||||
| NFPA 704 |
|
5-FORMYL-2-THIOPHENECARBOXYLIC ACID price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | F0336 | 5-Formyl-2-thiophenecarboxylic Acid >98.0%(GC)(T) | 4565-31-5 | 1g | $85 | 2025-07-31 | Buy |
| TCI Chemical | F0336 | 5-Formyl-2-thiophenecarboxylic Acid >98.0%(GC)(T) | 4565-31-5 | 5g | $215 | 2025-07-31 | Buy |
| TRC | F701050 | 5-FormylthenoicAcid | 4565-31-5 | 25mg | $125 | 2021-12-16 | Buy |
| SynQuest Laboratories | 6H21-1-X0 | 5-Formylthiophene-2-carboxylic acid | 4565-31-5 | 1g | $93 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | JK424250 | 5-Formyl-2-thiophenecarboxylic Acid 98% | 4565-31-5 | 1g | $129 | 2021-12-16 | Buy |
5-FORMYL-2-THIOPHENECARBOXYLIC ACID Chemical Properties,Uses,Production
Chemical Properties
Bright red solid
Uses
5-Formyl-2-thiophenecarboxylic acid is a thiophene derivative as immunomodulating agents useful in the treatment of autoimmune diseases.
Synthesis
67808-64-4
4565-31-5
General procedure for the synthesis of 5-formyl-2-thiophenecarboxylic acid from methyl 5-formylthiophene-2-carboxylate: the compound methyl 5-formylthiophene-2-carboxylic acid (2 g, 12.8 mmol) was dissolved in 200 mL of a mixed solvent (THF:H2O = 1:1), and the hydrolysis reaction was carried out by adding KOH (1.1 g, 19.2 mmol). Upon completion of the reaction, THF was removed by distillation under reduced pressure.Subsequently, the pH of the aqueous layer was adjusted to 1-2 with 1N HCl solution and extracted with ethyl acetate (200 mL × 5), resulting in the target compound 5-formyl-2-thiophenecarboxylic acid (1.2 g, 59% yield).1H NMR (300 MHz, CDCl3) δ 10.00 (s, 1H), 7.93- 7.92 (d, J = 3.92 Hz, 1H), 7.78-7.77 (d, J = 3.9 Hz, 1H).13C NMR (300 MHz, CDCl3) δ 182.2, 163.30, 141.57, 139.70, 133.79, 132.
References
[1] Patent: WO2004/37808, 2004, A1. Location in patent: Page 14-15; 93
5-FORMYL-2-THIOPHENECARBOXYLIC ACID Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hinova Pharma | +86-18190684138 +86-18190684138 | xhchen00241@hinovapharma.com | China | 60 | 58 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29798 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10035 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
View Lastest Price from 5-FORMYL-2-THIOPHENECARBOXYLIC ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-14 | 5-FORMYL-2-THIOPHENECARBOXYLIC ACID
4565-31-5
|
US $0.00-0.00 / g | 1g | 99.0 | 1000kg | Hinova Pharma | |
 |
2020-01-09 | 5-FORMYL-2-THIOPHENECARBOXYLIC ACID
4565-31-5
|
US $3.00 / KG | 1KG | 98% | 200KG | Career Henan Chemical Co |
-
- 5-FORMYL-2-THIOPHENECARBOXYLIC ACID
4565-31-5
- US $0.00-0.00 / g
- 99.0
- Hinova Pharma
-
- 5-FORMYL-2-THIOPHENECARBOXYLIC ACID
4565-31-5
- US $3.00 / KG
- 98%
- Career Henan Chemical Co
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