ChemicalBook >> CAS DataBase List >>Acetamiprid


Chemical Name:
(E)-N1-[(6-chloro-3-pyridyl)methyl]-N2-cyano-N1-methylacetamidine;Prize;Pristine;Piorun;NFK 17;MORTAL;TD 2480;TD 2472;Stonkat;MOSPILAN
Molecular Formula:
Molecular Weight:
MDL Number:
MOL File:
Modify Date:2023-05-18

Acetamiprid Properties

Melting point 101-103°C
Boiling point 352.4±52.0 °C(Predicted)
Density 1.17
vapor pressure <1 x 10-6 Pa (25 °C)
storage temp. Inert atmosphere,2-8°C
solubility DMSO: Soluble; Methanol: Soluble
form A solid
pka -0.44±0.10(Predicted)
Water Solubility 4200 mg l-1 (25 °C)
InChI InChI=1S/C10H11ClN4/c1-8(14-7-12)15(2)6-9-3-4-10(11)13-5-9/h3-5H,6H2,1-2H3/b14-8+
CAS DataBase Reference 135410-20-7(CAS DataBase Reference)
NIST Chemistry Reference Acetamipride(135410-20-7)
EPA Substance Registry System Acetamiprid (135410-20-7)


Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
Signal word  Danger
Hazard statements  H301-H330-H412
Precautionary statements  P260-P273-P284-P301+P310-P310
Hazard Codes  T
Risk Statements  23/25-57-52/53
Safety Statements  45-61
RIDADR  2588
RTECS  KJ4235200
HazardClass  6.1(b)
PackingGroup  III
HS Code  29333990

Acetamiprid price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 24129 Acetamiprid ≥98% 135410-20-7 10mg $24 2023-01-06 Buy
Cayman Chemical 24129 Acetamiprid ≥98% 135410-20-7 50mg $58 2023-01-06 Buy
Cayman Chemical 24129 Acetamiprid ≥98% 135410-20-7 100mg $81 2023-01-06 Buy
TRC A150800 Acetamiprid 135410-20-7 5g $1210 2021-12-16 Buy
Biosynth Carbosynth FA16947 Acetamiprid 135410-20-7 250mg $50 2021-12-16 Buy
Product number Packaging Price Buy
24129 10mg $24 Buy
24129 50mg $58 Buy
24129 100mg $81 Buy
A150800 5g $1210 Buy
FA16947 250mg $50 Buy

Acetamiprid Chemical Properties,Uses,Production

The new pesticide

Acetamiprid, also known as mospilan, is a new kind of pesticides. It is nitro methylene heterocyclic compounds. It can act on nicotinic acetylcholine receptor of the insect nervous system synapses, interfere the insect nervous system stimulation conduction, cause neurological pathways obstruction, and result in the accumulation of the neurotransmitter acetylcholine in the synapse. Then it can result in the paralysis of insect and eventually death. Acetamiprid has tag and stomach toxicity effect. Meanwhile it has a strong penetration, readily availability, and long duration.
Acetamiprid can be used for the prevention and control of aphids, planthoppers, thrips, lepidopteron and other pests on the rice, vegetables, fruit, tea bushes. At the concentration of 50 to 100 mg/L, acetamiprid can effectively control aphid, vegetables aphid, peach borer and it can kill eggs.

Physicochemical property

The original drug acetamiprid is white crystalline. Its content is more than 99%, melting point is 101~103.3℃, and vapor pressure is less than 0.33×10-6Pa (25℃). Acetamiprid is slightly soluble in water, and its solubility in the water is 4.2g/L. Acetamiprid is also soluble in acetone, methanol, ethanol, dichloromethane, chloroform, acetonitrile and the like. It is stable in the neutral or slightly acidic medium, and it can be stored at room temperature for 2 years. It can gradually hydrolyze when pH is 9 at 45℃. It is stable in sunlight.
The above information is edited by the Chemicalbook Ge Qian.


According to our pesticide toxicity grading standards, acetamiprid is moderately toxic pesticides. Acute oral LD50 of rat is 146~217mg/kg weight. It has no irritation on the skin and eye. It has no mutagenic effect according to the animal tests. Acetamiprid has low toxicity to human and animal, small lethality to predators, low toxicity to fish and little effect on bees. Acetamiprid can be used to control homopteran pests of fruit trees and vegetables. It can be used to control soil insect when using granules as soil.


1. Control of cucumber aphid. Pesticides should be sprayed during the full incidence beginning period of cucumber aphids. 40~50ml of 3% Acetamiprid, added 50~60kg water can be uniform sprayed. It will have a good effect on melon aphid. The efficacy can remain more than fifty days even in wet years,.
2. Control of apple aphids. 3% Mospilan with 2000~2500 times spray can be used during the apple tree growing period and the full incidence beginning period of aphids. It has a good effect on aphids and has good resistance to rain erosion. The efficacy can remain more than twenty days.
3. Control citrus aphids. 3% Mospilan with 2000~2500 times spray can be used during the full incidence beginning period of aphids. It has a good and persistent effect on citrus. It is safe for citrus. It has no phytotoxicity under normal use.


1. If there are mulberry fields nearby, acetamiprid should not be sprayed on mulberry leaves because this agent is toxic for the silkworm.
2. Acetamiprid can’t be mixed with strong base agents (bordeaux mixture, lime sulfur, etc.).
3. The toxicity of acetamiprid to human and animal is low. But if it is drinked, one should be taken to the hospital to be given gastric lavage immediately and keep quiet.


1. Acetamiprid belongs to the same series with imidacloprid. But its nsecticidal spectruma is broader than imidacloprid. It mainly has a better effect on cucumbers aphids, apples aphids, citrus aphids and tobacco aphids. Since the mechanism of acetamiprid is unique, it have a good effect on pests that can cause resistance to organophosphorus, carbamates and pyrethroids pesticides.
2. Efficient, broad-spectrum chlorinated insecticides.

Chemical Properties

Pale Yellow Solid


A novel neonicotinid insecticide against Holotrichia consanguinea in sugarcane. Reports show that when exposed to neonicotinid pesticides honeybees have probelms returnign home after foraging and bumb lebee colonies grow poorly and produce fewer queens.


Acetamiprid is a systemic insecticide for soil and foliar application. It is used to control Hemiptera, especially aphids, Thysanoptera and Lepidoptera on a wide range of crops, especially vegetables, fruit and tea.


ChEBI: The (E)-stereoisomer of acetamiprid.

Agricultural Uses

Insecticide: This class of pesticides are chemically related to nicotine and used on corn and soybean seeds and are used to control sucking and chewing insects, and soil insects including aphids, beetles, fruit moth, leaf-hoppers and-miners, thrips, whiteflies [83] . Also used to control fleas on domestic animals.

Metabolic pathway

Acetamiprid is relatively stable to hydrolysis and to photodegradation by sunlight. It is rapidly degraded in soils to form 6-chloropyridinyldimethylamine and 6-chloronicotinic acid. The main pathways of metabolism in plants are N-demethylation and subsequent oxidation affording 6-chloronicotinic acid and 6-chloropicolyl alcohol. Two N-cyanoamidines were formed after application of acetamiprid to cabbage leaves. No information is available on the fate of the insecticide in insects or mammals.


Acetamiprid is stable in buffer solutions at pH 4, 5 and 7 and under sunlight. It is degraded slowly at pH 9 (45 °C) (PM). In a study of its hydrolysis acetamiprid was converted quantitatively to N-methyl- (6-chloro-3-pyridyl)methylamine (2) in 0.5-1 N sodium hydroxide at 90-95°C in 2 hours (see Scheme 1). N-Demethyl-acetamiprid (3) was converted to (6-chloro-3-pyridyl)methylamine(4) at the same rate and under similar conditions (Tokieda et al., 1997).

Synthesis of Acetamiprid from Ethyl N-cyanoethanimideate and N-[(6-CHLOROPYRIDIN-3-YL)METHYL]-N-METHYLAMINE

Acetamiprid Preparation Products And Raw materials

Global( 426)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 China 21975 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763 China 2990 55
career henan chemical co
+86-0371-86658258 China 29922 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254 CHINA 28185 58
(323) 306-3136 United States 26 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 China 8898 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 China 6387 58
Hubei xin bonus chemical co. LTD
86-13657291602 CHINA 22973 58
Shanghai Longyu Biotechnology Co., Ltd.
+8615821988213 China 2532 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 China 39919 58

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Acetamiprid pictures 2023-05-29 Acetamiprid
US $15672.00 / Tons 1Tons 99.99% 100Tons Hebei Dangtong Import and export Co LTD
Acetamiprid pictures 2023-03-27 Acetamiprid
Acetamiprid  pictures 2023-03-06 Acetamiprid
US $50.00 / KG 1KG 99.% 10 ton Hebei Crovell Biotech Co Ltd
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  • US $15672.00 / Tons
  • 99.99%
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  • 99.9
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  • Hebei Crovell Biotech Co Ltd
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