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Methyl 3-bromopropionate

CAS No.
3395-91-3
Chemical Name:
Methyl 3-bromopropionate
Synonyms
Methyl 3-bromopropanoate;3-bromopropionate;NSC 3705;Methyl 3-bromopropio;Bromo-3-methylaniline;Methyl Bromopropionate;methyl3-bromopropanoate;METHYL 3-BROMOPROPIONATE;Methyl3-bromopropionate,97%;METHYL BETA-BROMOPROPIONATE
CBNumber:
CB9362390
Molecular Formula:
C4H7BrO2
Molecular Weight:
167
MDL Number:
MFCD00000250
MOL File:
3395-91-3.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:47

Methyl 3-bromopropionate Properties

Melting point 75°C
Boiling point 64-66 °C/18 mmHg (lit.)
Density 1.53 g/mL at 25 °C (lit.)
refractive index n20/D 1.458(lit.)
Flash point 167 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
form Liquid
color Clear colorless to slightly yellow
Water Solubility Immiscible
BRN 1742949
CAS DataBase Reference 3395-91-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII Y803CH1P4W
NIST Chemistry Reference Propanoic acid, 3-bromo-, methyl ester(3395-91-3)
EPA Substance Registry System Propanoic acid, 3-bromo-, methyl ester (3395-91-3)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-37/39-24/25
WGK Germany  3
RTECS  UA2451790
TSCA  Yes
HS Code  29159080
NFPA 704
1
2 0

Methyl 3-bromopropionate price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 242373 Methyl 3-bromopropionate 97% 3395-91-3 25g $87.5 2024-03-01 Buy
Sigma-Aldrich 242373 Methyl 3-bromopropionate 97% 3395-91-3 5g $34.4 2023-06-20 Buy
TCI Chemical B0648 Methyl 3-Bromopropionate >99.0%(GC) 3395-91-3 25g $71 2024-03-01 Buy
TCI Chemical B0648 Methyl 3-Bromopropionate >99.0%(GC) 3395-91-3 100g $238 2024-03-01 Buy
Alfa Aesar L14127 Methyl 3-bromopropionate, 97% 3395-91-3 25g $64.7 2024-03-01 Buy
Product number Packaging Price Buy
242373 25g $87.5 Buy
242373 5g $34.4 Buy
B0648 25g $71 Buy
B0648 100g $238 Buy
L14127 25g $64.7 Buy

Methyl 3-bromopropionate Chemical Properties,Uses,Production

Chemical Properties

Very slightly yellow liquid

Uses

Methyl 3-bromopropionate was used in the synthesis of spiroanellated γ-lactones, pinacols and unprecedented 3-(1-hydroxycycloalkyl)-l-oxaspiro[n,m]alkan-2-ones.

Synthesis

Methyl propionate

554-12-1

Methyl 3-bromopropionate

3395-91-3

Methyl propiolate (52 mL, 0.583 mol) was mixed with recrystallized N-bromosuccinimide (120 g, 0.674 mol) in 1,700 mL of acetone under nitrogen protection. Pure silver nitrate (9.9 g, 0.0583 mol) was added to the solution in a single addition and the reaction mixture was stirred at room temperature for 6 hours. Upon completion of the reaction, the acetone was evaporated under reduced pressure (25 °C bath temperature) to give a gray slurry. The slurry was washed with hexane (2 x 200 mL), filtered to remove the gray solid, and the filtrate was concentrated under vacuum to give 95 g of a pale yellow oily crude product. The crude product was passed through a short distillation under reduced pressure (65 °C, ca. 25 mmHg) and the fractions were collected with a receiver cooled with dry ice/acetone to give 83.7 g (88% yield) of methyl 3-bromopropynoate as a pale yellow oil. Calculated values for elemental analysis of [C4H3BrO2]: C, 29.48; H, 1.86. Measured values: C, 29.09; H, 1.97.

References

[1] Patent: WO2004/13137, 2004, A1. Location in patent: Page 76
[2] Tetrahedron Letters, 2010, vol. 51, # 13, p. 1793 - 1796

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View Lastest Price from Methyl 3-bromopropionate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 3-bromopropionate pictures 2025-07-07 Methyl 3-bromopropionate
3395-91-3
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mujin Biotechnology Co.,Ltd
Methyl 3-bromopropionate pictures 2025-07-07 Methyl 3-bromopropionate
3395-91-3
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mujin Biotechnology Co.,Ltd
Methyl 3-bromopropionate pictures 2025-06-24 Methyl 3-bromopropionate
3395-91-3
US $10.00 / KG 1KG 99% 100 mt Hebei Chuanghai Biotechnology Co., Ltd
3-bromopropanoicacidmethylester 3-bromo-propanoicacimethylester 3-bromo-propionicacimethylester methyl3-bromopropanoate Propionic acid, 3-bromo-, methyl ester METHYL 3-BROMOPROPIONATE METHYL BETA-BROMOPROPIONATE 3-BROMOPROPIONIC ACID METHYL ESTER BETA-BROMOPROPIONIC ACID METHYL ESTER Methyl3-bromopropionate,97% Propanoic acid, 3-bromo-, methyl ester Methyl Bromopropionate Methyl 3-bromopropio METHYL 3-BROMOPROPIONATE FOR SYNTHESIS NSC 3705 Propionic acid, 3-broMo-, Methyl ester (6CI,7CI,8CI) Methyl 3-broMopropionate 97% Methyl 3-broMopropionate, 98%+ 3 - broMine propionic acid Methyl ester Methyl 3-Bromopropionate > Methyl 3-bromopropanoate 3-bromopropionate Bromo-3-methylaniline Methyl 3-bromopropionate, 95% 3395-91-3 BrCH2CH2COOCH3 BrCH22CO2CH3 C2 to C5 Carbonyl Compounds Analytical Standards Building Blocks Analytical Chromatography Product Catalog Alphabetic HALOGEN Esters META - METH Organic Building Blocks Building Blocks C2 to C5 Carbonyl Compounds Chemical Synthesis Organic Building Blocks Organics C2 to C5 Carbonyl Compounds Esters bc0001