Methyl 3-bromopropionate
- CAS No.
- 3395-91-3
- Chemical Name:
- Methyl 3-bromopropionate
- Synonyms
- Methyl 3-bromopropanoate;3-bromopropionate;NSC 3705;Methyl 3-bromopropio;Bromo-3-methylaniline;Methyl Bromopropionate;methyl3-bromopropanoate;METHYL 3-BROMOPROPIONATE;Methyl3-bromopropionate,97%;METHYL BETA-BROMOPROPIONATE
- CBNumber:
- CB9362390
- Molecular Formula:
- C4H7BrO2
- Molecular Weight:
- 167
- MDL Number:
- MFCD00000250
- MOL File:
- 3395-91-3.mol
- MSDS File:
- SDS
| Melting point | 75°C |
|---|---|
| Boiling point | 64-66 °C/18 mmHg (lit.) |
| Density | 1.53 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | 167 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Liquid |
| color | Clear colorless to slightly yellow |
| Water Solubility | Immiscible |
| BRN | 1742949 |
| CAS DataBase Reference | 3395-91-3(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | Y803CH1P4W |
| NIST Chemistry Reference | Propanoic acid, 3-bromo-, methyl ester(3395-91-3) |
| EPA Substance Registry System | Propanoic acid, 3-bromo-, methyl ester (3395-91-3) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-37/39-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UA2451790 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29159080 | |||||||||
| NFPA 704 |
|
Methyl 3-bromopropionate price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 242373 | Methyl 3-bromopropionate 97% | 3395-91-3 | 25g | $87.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | 242373 | Methyl 3-bromopropionate 97% | 3395-91-3 | 5g | $34.4 | 2023-06-20 | Buy |
| TCI Chemical | B0648 | Methyl 3-Bromopropionate >99.0%(GC) | 3395-91-3 | 25g | $71 | 2024-03-01 | Buy |
| TCI Chemical | B0648 | Methyl 3-Bromopropionate >99.0%(GC) | 3395-91-3 | 100g | $238 | 2024-03-01 | Buy |
| Alfa Aesar | L14127 | Methyl 3-bromopropionate, 97% | 3395-91-3 | 25g | $64.7 | 2024-03-01 | Buy |
Methyl 3-bromopropionate Chemical Properties,Uses,Production
Chemical Properties
Very slightly yellow liquid
Uses
Methyl 3-bromopropionate was used in the synthesis of spiroanellated γ-lactones, pinacols and unprecedented 3-(1-hydroxycycloalkyl)-l-oxaspiro[n,m]alkan-2-ones.
Synthesis
554-12-1
3395-91-3
Methyl propiolate (52 mL, 0.583 mol) was mixed with recrystallized N-bromosuccinimide (120 g, 0.674 mol) in 1,700 mL of acetone under nitrogen protection. Pure silver nitrate (9.9 g, 0.0583 mol) was added to the solution in a single addition and the reaction mixture was stirred at room temperature for 6 hours. Upon completion of the reaction, the acetone was evaporated under reduced pressure (25 °C bath temperature) to give a gray slurry. The slurry was washed with hexane (2 x 200 mL), filtered to remove the gray solid, and the filtrate was concentrated under vacuum to give 95 g of a pale yellow oily crude product. The crude product was passed through a short distillation under reduced pressure (65 °C, ca. 25 mmHg) and the fractions were collected with a receiver cooled with dry ice/acetone to give 83.7 g (88% yield) of methyl 3-bromopropynoate as a pale yellow oil. Calculated values for elemental analysis of [C4H3BrO2]: C, 29.48; H, 1.86. Measured values: C, 29.09; H, 1.97.
References
[1] Patent: WO2004/13137, 2004, A1. Location in patent: Page 76
[2] Tetrahedron Letters, 2010, vol. 51, # 13, p. 1793 - 1796
Methyl 3-bromopropionate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8617732866630 | abby@chuanghaibio.com | China | 8773 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 | 1057@dideu.com | China | 3944 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86-13288715578 | sales@hbmojin.com | China | 12648 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20202 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29731 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 12828 | 58 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
| JingJiang Connect Chemical manufacturing Co., Ltd. | 0523-80501690 15252623102 | andy@katchemical.com | CHINA | 59 | 55 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
View Lastest Price from Methyl 3-bromopropionate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-07 | Methyl 3-bromopropionate
3395-91-3
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-07-07 | Methyl 3-bromopropionate
3395-91-3
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-06-24 | Methyl 3-bromopropionate
3395-91-3
|
US $10.00 / KG | 1KG | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Methyl 3-bromopropionate
3395-91-3
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- Methyl 3-bromopropionate
3395-91-3
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- Methyl 3-bromopropionate
3395-91-3
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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