ChemicalBook >> CAS DataBase List >>SC 19220
SC 19220
- CAS No.
- 19395-87-0
- Chemical Name:
- SC 19220
- Synonyms
- SC 19220;2-acetylhydrazide 10(11h)-carboxylic acid;8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid;N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide;8-CHLORO-DIBENZ[B,F][1,4]OXAZEPINE-10[11H]-CARBOXY-(2-ACETYL)HYDRAZIDE;8-CHLORO-DIBENZ[B,F][1,4]OXAZEPINE-10(11H)-CARBOXYLIC ACID, 2-ACETYLHYDRAZIDE;8-CHLORO-DIBENZO[B,F][1,4]OXAZEPINE-10(11H)-CARBOXYLIC ACID, 2-ACETYLHYDRAZIDE;Dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide;8-Chloro-dibenzo(Z)[b,f][1,4]oxazepine-10(11H)-carboxylicacid,2-acetylhydrazide;2-Acetylhydrazide 10(11H)-carboxylic acid, 8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid
- CBNumber:
- CB9372348
- Molecular Formula:
- C16H14ClN3O3
- Molecular Weight:
- 331.75
- MDL Number:
- MFCD02259329
- MOL File:
- 19395-87-0.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
SC 19220 price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S3065 | SC 19220 ≥98% (HPLC), solid | 19395-87-0 | 10mg | $82.4 | 2024-03-01 | Buy |
| Sigma-Aldrich | S3065 | SC 19220 ≥98% (HPLC), solid | 19395-87-0 | 50mg | $832 | 2023-01-07 | Buy |
| Cayman Chemical | 14060 | SC 19220 ≥96% | 19395-87-0 | 1mg | $20 | 2024-03-01 | Buy |
| Cayman Chemical | 14060 | SC 19220 ≥96% | 19395-87-0 | 5mg | $85 | 2024-03-01 | Buy |
| Cayman Chemical | 14060 | SC 19220 ≥96% | 19395-87-0 | 10mg | $146 | 2024-03-01 | Buy |
SC 19220 Chemical Properties,Uses,Production
Uses
SC 19220 is a selective EP1?receptor antagonist.
Uses
SC 19220 was used to study the role of prostaglandin E2 in oxygen-glucose deprivation-induced neurotoxicity and preconditioning-induced neuroprotection in rat cortical cultures.
Definition
ChEBI: N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide is an aromatic ether.
Biological Activity
Selective EP 1 receptor antagonist (IC 50 = 6.7 μ M for inhibition of [ 3 H]-PGE 2 binding to EP 1 transfected COS cells).
Biochem/physiol Actions
SC 19220 is a competitive antagonist of prostaglandin E receptors. It competes with PGE2 in regulating vesicourethral motility and increases the bladder capacity of rats. It inhibits the contraction of smooth muscles in response to prostaglandins E2 and F2α. SC 19220 also inhibits the formation of osteoclasts induced by vitamin D3, parathyroid hormone, IL-11 and IL-6.
storage
Store at RT
SC 19220 Preparation Products And Raw materials
Raw materials
Preparation Products
SC 19220 Suppliers
Global( 45)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4428 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44894 | 58 |
19395-87-0(SC 19220)Related Search:
8-CHLORO-DIBENZ[B,F][1,4]OXAZEPINE-10[11H]-CARBOXY-(2-ACETYL)HYDRAZIDE
8-CHLORO-DIBENZ[B,F][1,4]OXAZEPINE-10(11H)-CARBOXYLIC ACID, 2-ACETYLHYDRAZIDE
8-CHLORO-DIBENZO[B,F][1,4]OXAZEPINE-10(11H)-CARBOXYLIC ACID, 2-ACETYLHYDRAZIDE
SC 19220
2-acetylhydrazide 10(11h)-carboxylic acid
2-Acetylhydrazide 10(11H)-carboxylic acid, 8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid
8-Chloro-dibenzo(Z)[b,f][1,4]oxazepine-10(11H)-carboxylicacid,2-acetylhydrazide
8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid
N'-acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide
Dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide
19395-87-0
C16H14N3O3Cl