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(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE

CAS No.
59474-01-0
Chemical Name:
(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE
Synonyms
XI-011;NSC 146109;NSC 146109 HYDROCHLORIDE;NSC 146109 (HYDROCHLORIDE);XI-011;XI-011 (NSC 146109 hydrochloride);S-(10-Methylanthracen-9-yl)methyl Isothiourea Hydrochloride;(10-Methylanthracen-9-yl)methyl Carbamimidothiote Hydrochloride;(10-Methylanthracen-9-yl)methyl carbamimidothioate hydrochloride;(10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride;(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE
CBNumber:
CB9385498
Molecular Formula:
C17H17ClN2S
Molecular Weight:
316.85
MDL Number:
MFCD07783997
MOL File:
59474-01-0.mol
MSDS File:
SDS
Last updated:2023-09-04 15:51:00

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Properties

storage temp. Desiccate at RT
solubility Soluble to 10 mM in ethanol and to 100 mM in DMSO
form Powder
FDA UNII E9QK2XW6VT

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H351
Precautionary statements  P201-P202-P264-P270-P280-P301+P312-P330-P308+P313-P405-P501
NFPA 704
0
2 0

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML2570 NSC 146109 hydrochloride ≥98% (HPLC) 59474-01-0 5MG $71.3 2023-06-20 Buy
Sigma-Aldrich SML2570 NSC 146109 hydrochloride ≥98% (HPLC) 59474-01-0 25MG $231 2023-06-20 Buy
Cayman Chemical 16430 NSC 146109 (hydrochloride) ≥98% 59474-01-0 5mg $73 2024-03-01 Buy
Cayman Chemical 16430 NSC 146109 (hydrochloride) ≥98% 59474-01-0 10mg $138 2024-03-01 Buy
Cayman Chemical 16430 NSC 146109 (hydrochloride) ≥98% 59474-01-0 25mg $324 2024-03-01 Buy
Product number Packaging Price Buy
SML2570 5MG $71.3 Buy
SML2570 25MG $231 Buy
16430 5mg $73 Buy
16430 10mg $138 Buy
16430 25mg $324 Buy

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

This molecule inhibits MDMX expression in breast cancer cells through activating p53 resulting in apoptosis in cancer cells.

Biological Activity

Cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay.

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Suppliers

Global( 47)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3136 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
+86-18341751992 +86-15382112998 757984502@qq.com China 892 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
VDM Biochemicals 0330-2528181 sales@vdmbio.com United States 510 64
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58

(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Spectrum

NSC 146109 HYDROCHLORIDE (10-Methylanthracen-9-yl)methyl Carbamimidothiote Hydrochloride (10-Methylanthracen-9-yl)methyl carbamimidothioate hydrochloride (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE (10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride NSC 146109 NSC 146109 (HYDROCHLORIDE);XI-011 XI-011 S-(10-Methylanthracen-9-yl)methyl Isothiourea Hydrochloride XI-011 (NSC 146109 hydrochloride) NSC-146109,proapoptotic,breast cancer,NSC 146109 hydrochloride,inhibit,MDM-2/p53,NSC146109,NSC 146109,p53,Inhibitor,Apoptosis 59474-01-0 C17H16N2SHCl Caspases/Apoptosis Cell Cycle Regulation