ANTI-NERVE GROWTH FACTOR-BETA
- CAS No.
- Chemical Name:
- ANTI-NERVE GROWTH FACTOR-BETA
- Synonyms
- ANTI-NGF;ANTI-NGF-B;ANTI-BETA-NGF;ANTI-NGF-BETA;ANTI-BETA-TNFRSF 16;ANTI-HUMAN BETA-NGF;ANTI-HUMAN NGF-BETA;ANTI-BETA-NGF, HUMAN;ANTI-NGF (AB-2), HUMAN;ANTI-NGF (AB-2) MOUSE MAB
- CBNumber:
- CB9396438
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00282385
- MOL File:
- Mol file
ANTI-NERVE GROWTH FACTOR-BETA price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | N8773 | Anti-Nerve Growth Factor-β antibody produced in goat affinity isolated antibody, lyophilized powder | 0.1MG | $568 | 2024-03-01 | Buy | |
Sigma-Aldrich | N3279 | Monoclonal Anti-Nerve Growth Factor-β antibody produced in mouse clone 25623, purified immunoglobulin, lyophilized powder | 0.5mg | $397.2 | 2024-03-01 | Buy | |
American Custom Chemicals Corporation | ATB0015952 | ANTI-BETA-NGF 95.00% | 5MG | $499.8 | 2021-12-16 | Buy |
ANTI-NERVE GROWTH FACTOR-BETA Chemical Properties,Uses,Production
Uses
Anti-NGF-β antibody may be used for neutralization assays; the ND50 is ~0.02-0.1 μg/ml. For immunoblotting the recommended antibody concentration is 0.1-0.2 μg/ml. The antibody is suitable for immunohistochemistry at a working concentration of 5-15 μg/ml. For ELISA, antibody concentration of 0.2-0.8 μg/ml may be used. Antibody dilution of 1:500 was used for immunoblotting of extracts of rat nerve cells.
General Description
Nerve Growth factor (NGF) is a growth factor that is essential for the development and maintenance of the nervous system. NGF is composed of three non-covalently linked α, β and γ subunits. The β subunit is responsible for the biological functions of NGF. Nerve growth factor (NGF) binds to either to NGF receptor (NGFR) or the Trk receptor and can elicit biological responses through each of the receptors independently. NGF is important in the survival and differentiation of neurons and neural crest-derived cells during embryonic and early postnatal development and maintenance of peripheral neurons. NGF is also implicated in inflammation and allergic reactions . Anti-Nerve Growth Factor-β antibody recognizes rat NGF-β. The antibody shows less than 1% cross reactivity with recombinant human β-NGF.
Biochem/physiol Actions
Nerve Growth factor (NGF) is a growth factor that is essential for the development and maintenance of the nervous system. NGF is composed of three non-covalently linked α, β and γ subunits. The β subunit is responsible for the biological functions of NGF. Nerve growth factor (NGF) binds to either to NGF receptor (NGFR) or the Trk receptor and can elicit biological responses through each of the receptors independently. NGF is important in the survival and differentiation of neurons and neural crest-derived cells during embryonic and early postnatal development and maintenance of peripheral neurons. NGF is also implicated in inflammation and allergic reactions.
ANTI-NERVE GROWTH FACTOR-BETA Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-NERVE GROWTH FACTOR-BETA Suppliers
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