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Epifluorohydrin

CAS No.
503-09-3
Chemical Name:
Epifluorohydrin
Synonyms
Oxirane, (fluoromethyl)-;WLN: T3OTJ B1F;Epifluorhydrine;EPIFLUOROHYDRIN;epifluorohydrine;FLUOROMETHYLOXIRAN;Epifluorohydrin98%;Epifluorohydrin,97%;EPIFLUOROHYDRIN 97%;(fluoromethyl)oxirane
CBNumber:
CB9397703
Molecular Formula:
C3H5FO
Molecular Weight:
76.07
MDL Number:
MFCD00005131
MOL File:
503-09-3.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

Epifluorohydrin Properties

Boiling point 85-86 °C (lit.)
Density 1.067 g/mL at 25 °C (lit.)
refractive index n20/D 1.368(lit.)
Flash point 40 °F
storage temp. 0-6°C
form liquid
color clear
CAS DataBase Reference 503-09-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 0ZZ4ROH5IL
NIST Chemistry Reference Oxirane, (fluoromethyl)-(503-09-3)
EPA Substance Registry System Epifluorohydrin (503-09-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS05,GHS06
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H314
Precautionary statements  P210-P233-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  F,T
Risk Statements  11-23/24/25-34
Safety Statements  16-26-45-38-36/37/39-33
RIDADR  UN 2924 3/PG 2
WGK Germany  3
RTECS  TZ3325000
Hazard Note  Flammable/Highly Toxic
HazardClass  6.1(a)
PackingGroup  I
HS Code  2910900090
NFPA 704
3
3 0

Epifluorohydrin price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E1101 Epifluorohydrin 98% 503-09-3 1g $325 2024-03-01 Buy
TRC E586550 Epifluorohydrin 503-09-3 1g $95 2021-12-16 Buy
AK Scientific 1377AQ Epifluorohydrin 503-09-3 1g $132 2021-12-16 Buy
SynQuest Laboratories 2109-3-20 Epifluorohydrin 98% 503-09-3 5G $135 2021-12-16 Buy
Apolloscientific PC3158 3-Fluoro-1,2-propenoxide 98% 503-09-3 5g $175 2021-12-16 Buy
Product number Packaging Price Buy
E1101 1g $325 Buy
E586550 1g $95 Buy
1377AQ 1g $132 Buy
2109-3-20 5G $135 Buy
PC3158 5g $175 Buy

Epifluorohydrin Chemical Properties,Uses,Production

Chemical Properties

clear colourless liquid

Uses

Epifluorohydrin is used as a reagent in the synthesis of N-arylphosphoramidates. In addition, it is used in the synthesis of orally bioavailable ALK inhibitors in the treatment of tumors.

General Description

Clear colorless liquid.

Air & Water Reactions

Highly flammable. Water soluble.

Reactivity Profile

A halogenated epoxide. Epoxides are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts. The chlorinated derivative has been shown to be incompatible with aniline, strong oxidizers, sulfuric acid, isopropylamine, zinc, aluminum, iron, etc. see epichlorohydrin.

Health Hazard

ACUTE/CHRONIC HAZARDS: Epifluorohydrin is a lacrimator. When heated to decomposition it emits toxic fumes.

Fire Hazard

Epifluorohydrin is flammable.

106-89-8
503-09-3
Synthesis of Epifluorohydrin from Epichlorohydrin
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(fluoromethyl)oxirane 1,2-epoxy-3-fluoro-propan 1-fluoro-2,3-epoxypropane 2-(Fluoromethyl)oxirane 3-Fluoropropene-1,2-oxide Epifluorhydrine Propane, 1,2-epoxy-3-fluoro- 3-Fluoropropylene oxide Epifluorohydrin,97% Epifluorohydrin,1,2-Epoxy-3-fluoropropane 3-Fluoro-1,2-propenoxide 2-(Fluoromethyl)oxirane, 3-Fluoro-1,2-epoxypropane 1,2-EPOXY-3-FLUOROPROPANE ALPHA-EPIFLUOROHYDRIN EPIFLUOROHYDRIN FLUOROMETHYLOXIRAN epifluorohydrine EPIFLUOROHYDRIN 97% 3-Fluoro-1,2-epoxypropane 2-(Fluoromethyl)oxirane, 1,2-Epoxy-3-fluoropropane, Glycidyl fluoride Oxirane, (fluoromethyl)- (9CI) WLN: T3OTJ B1F Epifluorohydrin98% 3-Fluoro-1,2-propenoxide 99% Oxirane, 2-(fluoromethyl)- Epifluorohydrin ISO 9001:2015 REACH Oxirane, (fluoromethyl)- 503-09-3 C3H5FO Epoxides Building Blocks Oxygen Compounds Organic Building Blocks Contact Printing Fluorine-Containing Monomers for 157 nm UV Lithography Resist Polymers Lithography Monomers Self Assembly & Building Blocks Chemical Synthesis Epoxides Fluorinated Building Blocks Heterocyclic Fluorinated Building Blocks Materials Science Micro/NanoElectronics Organic Building Blocks Other Fluorinated Heterocycles Oxygen Compounds monomer