ChemicalBook >> CAS DataBase List >>DEXCHLORPHENIRAMINE

DEXCHLORPHENIRAMINE

DEXCHLORPHENIRAMINE structure

CAS No.: 25523-97-1

Chemical Name:: DEXCHLORPHENIRAMINE

Synonyms: C06946;fortamine;isomerine;chlo-amine;phendextro;Mylaramine;S-Chlorpheniramine;d-chlorpheniramine;exchlorpheniramine;DEXCHLORPHENIRAMINE

CBNumber:: CB9399974

Molecular Formula:: C16H19ClN2

Molecular Weight:: 274.79

MDL Number:: MFCD00865695

MOL File:: 25523-97-1.mol

Last updated:2023-05-04 17:34:36

Request For Quotation

DEXCHLORPHENIRAMINE Properties

alpha	D25 +49.8° (c = 1 in DMF)
Boiling point	142 °C(Press: 1.0 Torr)
Density	1.107±0.06 g/cm3(Predicted)
pka	9.33±0.28(Predicted)
FDA UNII	3Q9Q0B929N
ATC code	R06AB02,R06AB52

DEXCHLORPHENIRAMINE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
American Custom Chemicals Corporation	API0006290	(+)-CHLORPHENIRAMINE 95.00%	25523-97-1	1G	$668.5	2021-12-16	Buy
American Custom Chemicals Corporation	API0006290	(+)-CHLORPHENIRAMINE 95.00%	25523-97-1	5G	$898.31	2021-12-16	Buy
American Custom Chemicals Corporation	API0006290	(+)-CHLORPHENIRAMINE 95.00%	25523-97-1	10G	$1280.79	2021-12-16	Buy

Product number	Packaging	Price	Buy
API0006290	1G	$668.5	Buy
API0006290	5G	$898.31	Buy
API0006290	10G	$1280.79	Buy

DEXCHLORPHENIRAMINE Chemical Properties,Uses,Production

Originator

Polaramine,Schering,US,1958

Uses

Activity of this drug is approximately twice that of chlorpheniramine. Dexchlorpheniramine is also used for allergy symptoms, rhinitis, and dermatitis.

Uses

Antihistaminic.

Definition

ChEBI: Dexchlorpheniramine is a chlorphenamine. It is an enantiomer of a levochlorpheniramine.

Manufacturing Process

Twenty grams of d-phenylsuccinic acid and 28 grams of 3-(2-pyridyl)-3-pchlorophenyl-N,N-dimethylpropylamine are dissolved in 400 ml of absolute ethyl alcohol and allowed to stand at room temperature until crystallization is effected. The crystals are filtered, washed with absolute ethyl alcohol and recrystallized from 300 ml of this solvent in the same manner. The crystals are recrystallized twice from 80% ethyl alcohol using 3.5 ml per gram of compound in the manner described above and pure d-3-(2-pyridyl)-3-pchlorophenyl-N,Ndimethylpropylamine-d-phenylsuccinate is obtained, melting point 145-147°C.
This salt is shaken with 100 ml of diethyl ether and 50 ml of 20% aqueous potassium carbonate; the ether layer is separated, dried over anhydrous potassium carbonate, filtered and the ether is removed in vacuo. The d-3-(2- pyridyl)-3-p-chlorophenyl-N,N-dimethylpropylamine so obtained is a mobile oil.
4.3 grams of the above base and 1.8 grams of maleic acid are dissolved in 20 ml isopropyl acetate and kept at room temperature until crystallization is complete. The crystals are filtered, washed with ethyl acetate and recrystallized from 15 ml of this solvent in the same manner. The crystalline d-3-(2-pyridyl)-3-p-chlorophenyl-N,N-dimethylpropylamine maleate so formed is then filtered off and dried. MP 113-115°C from US Patent 3,030,371.

brand name

Mylaramine (Morton Grove); Polaramine (Schering).

Therapeutic Function

Antihistaminic

DEXCHLORPHENIRAMINE synthesis

Synthesis of DEXCHLORPHENIRAMINE from 4-Chlorophenylboronic acid

DEXCHLORPHENIRAMINE Preparation Products And Raw materials

Raw materials

Maleic acid Potassium carbonate R-Chlorpheniramine (E)-ethyl 3-(2-pyridyl)-propenoate Chloropheniramine

4-Chlorophenylboronic acid

1of2

Preparation Products

DEXCHLORPHENIRAMINE Suppliers

Global( 24)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569265 +86-18612256290	1056@dideu.com	China	3632	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9358	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29271	58
Hebei Guanlang Biotechnology Co,.LTD	+8619930503252	daisy@crovellbio.com	China	5964	58
Shanghai Hekang Biotechnology Co., Ltd.	18939837085	youchemicals@gmail.com	China	1813	55
HX Pharmaceutical technology co., LTD	15671363360	494267389@qq.com	China	2212	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	4028	58
Hubei YuanCheng Pharmaceutical Co., Ltd.	18062666904	wyy01@ycphar.com	China	669	65

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
TargetMol Chemicals Inc.	58
Shaanxi Dideu Medichem Co. Ltd	58
Dideu Industries Group Limited	58
Hebei Guanlang Biotechnology Co,.LTD	58
Shanghai Hekang Biotechnology Co., Ltd.	55
HX Pharmaceutical technology co., LTD	58
Nantong QuanYi Biotechnology Co., Ltd	58
Hubei YuanCheng Pharmaceutical Co., Ltd.	65

View Lastest Price from DEXCHLORPHENIRAMINE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-03-06	Voriconazole 25523-97-1	US $10.50 / KG	1KG	99	1 ton	Hebei Guanlang Biotechnology Co,.LTD
2021-07-20	Dexchlorpheniramine 25523-97-1	US $1.00-1.00 / KG	1g	99%	50tons	Shaanxi Dideu Medichem Co. Ltd
2021-06-18	DEXCHLORPHENIRAMINE USP/EP/BP 25523-97-1	US $1.10 / g	1g	99.9%	100 Tons Min	Dideu Industries Group Limited

Voriconazole
25523-97-1
US $10.50 / KG
99
Hebei Guanlang Biotechnology Co,.LTD

Dexchlorpheniramine
25523-97-1
US $1.00-1.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

DEXCHLORPHENIRAMINE USP/EP/BP
25523-97-1
US $1.10 / g
99.9%
Dideu Industries Group Limited

25523-97-1(DEXCHLORPHENIRAMINE)Related Search:

HexanitrodiphenylaMine BROMPHENIRAMINE MALEATE IMP. B (EP) AS MALEATE: DEXCHLORPHENIRAMINE MALEATE IMP. B (EP): DEXCHLORPHENIRAMINE CL DEXCHLORPHENIRAMINE TANNATE DEXCHLORPHENIRAMINE MALEATE IMP. A (EP) AS MALEATE: (3RS)-N,N-DIMETHYL-3-PHENYL-3-(PYRIDIN-2-YL)PROPAN-1-AMINE MALEATE

Dexchlorpheniramine Maleate Pheniramine maleate DEXCHLORPHENIRAMINE

1of2

chlo-amine 2-Pyridinepropanamine, γ-(4-chlorophenyl)-N,N-dimethyl-, (γS)- Pyridine, 2-[p-chloro-α-[2-(dimethylamino)ethyl]benzyl]-, (S)-(+)- (8CI) S-(+)-Chlorpheniramine S-Chlorpheniramine Dexchlorpheniramine (base and/or unspecified salts) (+)-2-[(S)-p-Chloro-α-[2-(dimethylamino)ethyl]benzyl]pyridine (S)-γ-(4-Chlorophenyl)-N,N-dimethyl-2-pyridinepropan-1-amine C06946 (3S)-3-(4-Chlorophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine d-2-[p-chloro-alpha-(2-dimethylaminoethyl)benzyl]pyridine d-chlorpheniramine fortamine isomerine n-dimethyl-gamma-(4-chlorophenyl)-(s)-2-pyridinepropanamin phendextro DEXCHLORPHENIRAMINE DEXCHLORPHENIRAMINE BASE (S)-Chloropheniramine 2-Pyridinepropanamine, γ-(4-chlorophenyl)-N,N-dimethyl-, (S)- (3S)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine exchlorpheniramine DEXCHLORPHENIRAMINE USP/EP/BP Dexchlorpheniramine free base Mylaramine 25523-97-1 C16H19ClN2