MENTHOFURAN | 494-90-6

MENTHOFURAN Properties

Melting point	86°C
Boiling point	80-82 °C13 mm Hg(lit.)
Density	0.97 g/mL at 25 °C(lit.)
refractive index	n20/D 1.485(lit.)
FEMA	3235 \| 4,5,6,7-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN
Flash point	168 °F
storage temp.	Room Temperature
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form	Liquid
color	Clear light yellow
Odor	at 1.00 % in dipropylene glycol. pungent musty nutty earthy coffee
Odor Type	musty
optical activity	[α]25/D +90°, c = 10 in methanol
JECFA Number	758
Stability	Not stable in solution
LogP	4.02
Substances Added to Food (formerly EAFUS)	4,5,6,7-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN
CAS DataBase Reference	494-90-6(CAS DataBase Reference)
FDA UNII	LK024V9U3C
EPA Substance Registry System	Benzofuran, 4,5,6,7-tetrahydro-3,6-dimethyl- (494-90-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS09

Hazard statements

H227

Precautionary statements

P210e-P280a-P370+P378a-P403+P235-P501a

Safety Statements

24/25

WGK Germany

2

RTECS

DF7995750

TSCA

Yes

HS Code

29329990

NFPA 704

	2
1		0

MENTHOFURAN price More Price(23)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	W323500	4,5,6,7-Tetrahydro-3,6-dimethylbenzofuran ≥95%	494-90-6	sample	$54.6	2023-06-20	Buy
Alfa Aesar	A17192	Menthofuran, 95%	494-90-6	1g	$42.65	2024-03-01	Buy
Alfa Aesar	A17192	Menthofuran, 95%	494-90-6	5g	$91.65	2024-03-01	Buy
Sigma-Aldrich	W323500	4,5,6,7-Tetrahydro-3,6-dimethylbenzofuran ≥95%	494-90-6	100g	$142	2023-06-20	Buy
Sigma-Aldrich	W323500	4,5,6,7-Tetrahydro-3,6-dimethylbenzofuran ≥95%	494-90-6	25g	$71	2023-01-07	Buy

Product number	Packaging	Price	Buy
W323500	sample	$54.6	Buy
A17192	1g	$42.65	Buy
A17192	5g	$91.65	Buy
W323500	100g	$142	Buy
W323500	25g	$71	Buy

MENTHOFURAN Chemical Properties,Uses,Production

Chemical Properties

4,5,6,7-Tetrahydro-3,6-dimethylbenzofuran has an odor very similar to that of menthol.

Chemical Properties

CLEAR LIGHT YELLOW LIQUID

Chemical Properties

Menthofuran occurs as the (+) isomer, in peppermint essential oils. It is a colorless liquid with a minty odor.

Occurrence

Reported found in peppermint oil, corn mint oil, spearmint oil, Scotch spearmint oil, pennyroyal oil and other Mentha oils and buchu oil.

Uses

Menthofuran is a toxin found in vairety of essential oils and is believed to be the compound responsible for the potentially fatal effects of Pennyroyal. Menthofuran is known to produce hepatotoxic intermedaites via oxidation process.

Uses

Menthofuran is a toxin found in vairety of essential oils and is believed to be the compound responsible for the potentially fatal effects of Pennyroyal. Menthofuran is known to produce hepatotoxic intermediates via oxidation process.

Preparation

(+)-Menthofuran [17957-94-7] is isolated fromMentha oils or is prepared synthetically, for example, by treatment of (+)-pulegone with fuming sulfuric acid in acetic anhydride and pyrolysis of the resulting sultone.

Definition

ChEBI: Menthofuran is a monoterpenoid that is 4,5,6,7-tetrahydro-1-benzofuran substituted by methyl groups at positions 3 and 6. It has a role as a nematicide and a plant metabolite. It is a member of 1-benzofurans and a monoterpenoid.

Taste threshold values

Taste characteristics at 10 ppm: musty, nutty, coffee, raw and legume

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 2442, 1983 DOI: 10.1021/jo00162a037

Synthesis

By thermal decomposition of the sulfone of 3-hydroxy-3,8(9)-methadiene-9-sulfonic acid; the latter is obtained by sulfonapulegone in acetic anhydride.

MENTHOFURAN synthesis

Synthesis of MENTHOFURAN from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

MENTHOFURAN Preparation Products And Raw materials

Raw materials

Benzofuran,3,6-dimethyl-

Preparation Products

MENTHOFURAN Suppliers

Global( 139)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9641	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58
VladaChem GmbH	+49-7246-3082843	info@vladachem.de	Germany	1860	58
Shaanxi Didu New Materials Co. Ltd	+86-89586680 +86-13289823923	1026@dideu.com	China	9309	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503259 +86-19930503259	cherry@crovellbio.com	China	18458	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Shanghai Zheyan Biotech Co., Ltd.	58
career henan chemical co	58
Hubei xin bonus chemical co. LTD	58
Chongqing Chemdad Co., Ltd	58
Antai Fine Chemical Technology Co.,Limited	58
ANHUI WITOP BIOTECH CO., LTD	58
VladaChem GmbH	58
Shaanxi Didu New Materials Co. Ltd	58
Hebei Guanlang Biotechnology Co., Ltd.	58

View Lastest Price from MENTHOFURAN manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-03-28	Menthofurane 494-90-6	US $0.00-0.00 / KG	25KG	98%	Inquiry	PNP Biotech Co. Ltd
2023-11-11	MENTHOFURAN 494-90-6	US $30.00-10.00 / kg	1kg	0.99	10 tons	Hebei Yanxi Chemical Co., Ltd.
2023-09-06	MENTHOFURAN 494-90-6	US $0.00 / KG	1KG	99%	500000kg	Hebei Guanlang Biotechnology Co., Ltd.

Menthofurane
494-90-6
US $0.00-0.00 / KG
98%
PNP Biotech Co. Ltd

MENTHOFURAN
494-90-6
US $30.00-10.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

MENTHOFURAN
494-90-6
US $0.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

MENTHOFURAN Spectrum

MENTHOFURAN(494-90-6)¹HNMR MENTHOFURAN(494-90-6)FT-IR MENTHOFURAN(494-90-6)IR

494-90-6(MENTHOFURAN)Related Search:

Geneticin Ethanol Citric acid Salicylic acid Furazolidone

Carbofuran FURFURYL ALCOHOL RESIN Edible essence 2(4H)-Benzofuranone, 5,6-dihydro-3,6-dimethyl-, (6R)- MENTHOFURAN

3,6,6-TRIMETHYL-4-OXO-4,5,6,7-TETRAHYDRO-BENZOFURAN-2-CARBOXYLIC ACID (2,6,6-TRIMETHYL-4-OXO-4,5,6,7-TETRAHYDRO-BENZOFURAN-3-YL)-ACETIC ACID 3-ACETYL-2,6,6-TRIMETHYL-5,6,7-TRIHYDROOXAINDEN-4-ONE (R)-(+)-MENTHOFURAN,(+)-MENTHOFURAN,(+)-MENTHOFURAN, TERPENE STANDARD 4-HYDROXY-3,6,6-TRIMETHYL-4,5,6,7-TETRAHYDRO-1-BENZOFURAN-2-CARBOXYLIC ACID

6,6-DIMETHYL-4-OXO-4,5,6,7-TETRAHYDRO-1-BENZOFURAN-3-CARBOXYLIC ACID menthofuran synthase MENTHOFURAN(4,5,6,7-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN)

1of4

3,6-Dimethyl-4,5,6,7-tetrahydro-1-benzofuran 3,9-Epoxy-p-mentha-3,8-diene 4,5,6,7-tetrahydro-3,6-dimethyl-benzofura p-Mentha-3,8-diene, 3,9-epoxy- FEMA 3235 MENTHOFURAN 4 5 6 7-TETRAHYDRO-3 6-DIMETHYLBENZOFUR& Menthofuran,95% 3,6-dimethyl-4,5,6,7-tetrahydrobenzofuran MENTHOFURAN(SG) MENTHOFURAN WITH GC MENTHOFURAN, NATURAL (6R)-3,6-Dimethyl-4,5,6,7-tetrahydrobenzofuran (R)-4,5,6,7-Tetrahydro-3,6-dimethylbenzofuran 4,5,6,7-Tetrahydro-3,6-dimethylbenzofuran,Menthofuran Menthofuran, 95% 10GR MENTHOFURA UNII:LK024V9U3C MENTHOFURAN Extra Pure Benzofuran, 4,5,6,7-tetrahydro-3,6-dimethyl- Menthofurane 4,5,6,7-TETRAHYDRO-3,6-DIMETHYLBENZOFURAN Inhibitor,peppermint oil biosynthesis,inhibit,monoterpene reductase,Menthofuran,Drug Metabolite 494-90-6