ChemicalBook >> CAS DataBase List >>D-2-Phenylglycine

D-2-Phenylglycine

CAS No.
875-74-1
Chemical Name:
D-2-Phenylglycine
Synonyms
(R)-2-AMino-2-phenylacetic acid;D-PHENYLGLYCINE;D-(-)-PHENYLGLYCINE;H-D-PHG-OH;(2R)-2-amino-2-phenylacetic acid;ycine;D-Phg-OH;D-2-Phenylglyc;D-(-)-α-PhenyL;PHENYLGLYCINE-D
CBNumber:
CB9413124
Molecular Formula:
C8H9NO2
Molecular Weight:
151.16
MDL Number:
MFCD00008061
MOL File:
875-74-1.mol
MSDS File:
SDS
Last updated:2024-03-19 15:37:51

D-2-Phenylglycine Properties

Melting point 302 °C (dec.)(lit.)
Boiling point 273.17°C (rough estimate)
alpha -156 º (c=1,1N HCl)
Density 1.2 g/cm3 (20℃)
vapor pressure 0Pa at 25℃
refractive index -158 ° (C=1, 1mol/L HCl)
Flash point 150 °C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Aqueous Acid (Sparingly), Water (Slightly, Heated)
form Crystalline Powder
pka 1.94±0.10(Predicted)
color White
optical activity [α]20/D 155°, c = 1 in 1 M HCl
Water Solubility 0.3g/100mL
Merck 14,7291
BRN 2208676
LogP -1.76 at 20℃
CAS DataBase Reference 875-74-1(CAS DataBase Reference)
FDA UNII GF5LYS471N
NIST Chemistry Reference d a-Phenylglycine(875-74-1)
EPA Substance Registry System Benzeneacetic acid, .alpha.-amino-, (.alpha.R)- (875-74-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H319-H315
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard Codes  T
Risk Statements  23/24/25-36/37/38-22-20
Safety Statements  22-24/25-45-36/37/39-26-44-28-7-4
WGK Germany  3
TSCA  Yes
HS Code  29224995
NFPA 704
1
0 0

D-2-Phenylglycine price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P25485 D?(?)-α-Phenylglycine 99% 875-74-1 25g $40.7 2024-03-01 Buy
Sigma-Aldrich P25485 D?(?)-α-Phenylglycine 99% 875-74-1 100g $111 2024-03-01 Buy
TCI Chemical P0820 D-2-Phenylglycine >99.0%(T) 875-74-1 25g $22 2024-03-01 Buy
TCI Chemical P0820 D-2-Phenylglycine >99.0%(T) 875-74-1 100g $54 2024-03-01 Buy
Alfa Aesar A15669 D-(-)-2-Phenylglycine, 99% 875-74-1 25g $24.65 2024-03-01 Buy
Product number Packaging Price Buy
P25485 25g $40.7 Buy
P25485 100g $111 Buy
P0820 25g $22 Buy
P0820 100g $54 Buy
A15669 25g $24.65 Buy

D-2-Phenylglycine Chemical Properties,Uses,Production

Description

L-phenylglycine (Cephalexin EP Impurity A) is a derivative of glycine, a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in the spinal cord and an allosteric modulator of NMDA receptors.

Storage

Store at room temperature. Store in cool dry place in tightly closed container. Store away from oxidizing agent.

Description

d-Phenylglycine is widely used in large quantity as the side chain that makes ampicillin and cephalexin orally acceptable.

Chemical Properties

White crystalline powder

Uses

D-(-)-2-Phenylglycine (Cefalexin EP Impurity A) is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Uses

D-(-)-2-Phenylglycine is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA r eceptors.

Definition

ChEBI: The R stereoisomer of alpha-phenylglycine.

Flammability and Explosibility

Non flammable

Synthesis

Industrially, dphenylglycine has been produced by a conventional resolution method or by kinetic resolution with acylase. Another enzymatic procedure has been developed by Yamada et al. , as shown below.
Synthesis_875-74-1

41804-94-8
875-74-1
Synthesis of D-2-Phenylglycine from 2-amino-2-phenylacetonitrile
Global( 459)Suppliers
Supplier Tel Email Country ProdList Advantage
DONBOO AMINO ACID COMPANY
+8613063595538 donboo@donboo.com China 9365 58
Shanghai UCHEM Inc.
+862156762820 +86-13564624040 sales@myuchem.com China 6645 58
Wuhan Han Sheng New Material Technology Co.,Ltd
+8617798174412 admin01@hsnm.com.cn China 2120 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2504 58
Sichuan HongRi Pharma-Tech Co.,Ltd
+86-028-64841719 +8618980456393 daisy@enlaibio.com China 1369 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 14764 58
Taizhou Tianhong Biochemistry Technology Co., Ltd.
0523-86132544 sales@thbiochem.com CHINA 305 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9354 55

View Lastest Price from D-2-Phenylglycine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
H-D-Phg-OH pictures 2024-03-28 H-D-Phg-OH
875-74-1
US $0.00-0.00 / kg 1kg 99% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
D-2-Phenylglycine pictures 2024-02-23 D-2-Phenylglycine
875-74-1
US $56.00 / kg 1kg 0.98 100kg Shanghai UCHEM Inc.
D(-)-alpha-Aminophenylacetic pictures 2023-09-14 D(-)-alpha-Aminophenylacetic
875-74-1
US $19.00 / kg 1kg 99% 100MT Wuhan Han Sheng New Material Technology Co.,Ltd
  • H-D-Phg-OH pictures
  • H-D-Phg-OH
    875-74-1
  • US $0.00-0.00 / kg
  • 99%
  • Sichuan HongRi Pharma-Tech Co.,Ltd
.alpha.-amino-,(R)-Benzeneaceticacid Benzeneacetic acid, alpha-amino-, (R)- Benzeneaceticacid,alpha-amino-,(R)- D-(-)-2-Phenylglycine,99% (R)-(-)-ALPHA-AMINOPHENYLACETIC ACID FOR RESOLUTION OF RACEMATES D(-)-alpha-Aminophenylacetic D-a-a(1,4-cyclohexadienyl)Glyc Benzeneacetic acid, .alpha.-amino-, (.alpha.R)- d-(-)-à-aminophenylacetic acid D-Phenylglycine Base Benzeneacetic acid, alpha-amino-, (alphaR)- (9CI) D-Phenylglycine, (R)-(-)-a-Aminophenylacetic acid D(-)-a-Aminophenyl ycsysnar acid D-Phenylglycine,99%e.e. (R)-(-)-α-Aminophenylacetic acid for resolution of racemates for synthesis PHENYLGLYCINE-D (R)-PHENYLGLYCINE (R)-(-)-ALPHA-AMINOPHENYLACETIC ACID (R)-ALPHA-AMINOPHENYLACETIC ACID (R)-(-)-ALPHA-PHENYLAMINOACETIC ACID (R)-AMINO-PHENYL-ACETIC ACID (R)-(-)-2-PHENYLGLYCINE H-D-(PHENYL)GLY-OH D-(-)-2-PHENYLGLYCINE D-2-PHENYLGLYCINE (-)-D-ALPHA-PHENYLGLYCINE D(-)-ALPHA-PHENYLGLYCINE (R)-(-)-2-Phenylglycine, D-2-Phenylglycine, R(-)-α-Aminophenylacetic acid D(-)-alpha-Phenylglycine,98% D-(-)-α-Phenylglycine ,99% D()-α-Phenylglycine,(R)-()-2-Phenylglycine, D-2-Phenylglycine, R-()-α-Aminophenylacetic acid R-(-)-|á-Aminophenylacetic acid D(-)-alpha-Phenylglycine, 98% 100GR D(-)-alpha-Phenylglycine, 98% 25GR (R)-(-)-A-AMINOPHENYLACETIC ACID FOR RES D-2-Phenylglyc Cefalexine EP IMpurity A Cefaclor EP IMpurity A (2R)-AMino-2-phenylethanoic acid Cephalexin IMpurity A (D-2-Phenylglycine) Benzeneacetic acid, a-aMino-, (aR)- D-(-)-alpha-Phenylglycine 99% D-(-)-alpha-Phenylglycine, 95+% C-Phenylglycine D-Phenylglycine≥ 99% (Assay) D-ALPHA-PHENYLGLYCINE D-AMINOPHENYLACETIC ACID D(-)-ALPHA-AMINOPHENYLACETIC ACID D-ALPHA-AMINOPHENYLACETIC ACID D-(-)-A-AMINOPHENYLACETIC ACID D-(-)-A-PHENYLAMINOACETIC ACID D-(-)-A-PHENYLGLYCINE Cefalexin EP Impurity A D-Phg-OH Cefaclor Impurity A (EP) Cephalexin EP Impurity A (Ampicillin EP Impurity L) Ampicillin Impurity 12(Ampicillin EP Impurity L) Ampicillin EP Impurity L (Cephalexin EP Impurity A)