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DL-NORPHENYLEPHRINE HYDROCHLORIDE

CAS No.
4779-94-6
Chemical Name:
DL-NORPHENYLEPHRINE HYDROCHLORIDE
Synonyms
WV 569;Coritat;Vingsal;Energona;Esbuphon;Stagural;Tonolift;Molycor R;NSC 100733;NSC 297582
CBNumber:
CB9429008
Molecular Formula:
C8H12ClNO2
Molecular Weight:
189.64
MDL Number:
MFCD00012879
MOL File:
4779-94-6.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:39

DL-NORPHENYLEPHRINE HYDROCHLORIDE Properties

Melting point 162-164 °C(lit.)
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
color White to Off-White
Merck 14,6699
FDA UNII 1FCN9TAU6R

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
RTECS  DN7400000
HS Code  2922504500
Toxicity LD50 oral in rat: 390mg/kg

DL-NORPHENYLEPHRINE HYDROCHLORIDE price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1473206 Norphenylephrine hydrochloride United States Pharmacopeia (USP) Reference Standard 4779-94-6 25mg $1490 2024-03-01 Buy
Sigma-Aldrich 113727 Norphenylephrine hydrochloride 98% 4779-94-6 10g $135 2024-03-01 Buy
Sigma-Aldrich PHR1536 Norphenylephrine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 4779-94-6 200mg $315 2024-03-01 Buy
TRC N825500 racNorphenylephrineHydrochloride(PhenylephrineImpurityA) 4779-94-6 250mg $425 2021-12-16 Buy
Biosynth Carbosynth IN27563 rac-Norphenylephrine hydrochloride 4779-94-6 100g $500 2021-12-16 Buy
Product number Packaging Price Buy
1473206 25mg $1490 Buy
113727 10g $135 Buy
PHR1536 200mg $315 Buy
N825500 250mg $425 Buy
IN27563 100g $500 Buy

DL-NORPHENYLEPHRINE HYDROCHLORIDE Chemical Properties,Uses,Production

Chemical Properties

white to almost white crystalline powder

Originator

Zordel,Grelan,Japan,1970

Uses

rac Norphenylephrine Hydrochloride is an Impurity A of phenylephrine. A phenylephrine derivative as leukotriene D4 antagonists.

Definition

ChEBI: Norfenefrine hydrochloride is a member of phenols.

Manufacturing Process

100 parts of the hydrochloride of meta-hydroxy-ω-aminoacetophenone of melting point 220°C to 222°C (obtainable by brominating metaacetoxyacetophenone, causing the bromoketone to react with sodium iodide, adding hexamethylenetetramine to the iodide in an indifferent solvent and scission of the addition product in acid solution) are shaken in aqueous solution with hydrogen in presence of 2 parts of palladium catalyst until 2 atomic proportions of hydrogen have been absorbed. The catalyst is now filtered and the filtrate evaporated in a vacuum; and the crystalline and completely dry residue is dissolved in absolute alcohol and a precipitate is produced by adding dry ether. The hydrochloride of metahydroxyphenylethanolamine thus obtained forms white crystals of melting point 159°C to 160°C.

Therapeutic Function

Adrenergic

DL-NORPHENYLEPHRINE HYDROCHLORIDE Preparation Products And Raw materials

Global( 95)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14336 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569265 +86-18612256290 1056@dideu.com China 3683 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 9409 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29322 58
Alfa Chemistry
+1-5166625404 Info@alfa-chemistry.com United States 21317 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503259 +86-19930503259 cherry@crovellbio.com China 18457 58
China National Standard Pharmaceutical Corporation Limited
+8615391658522 overseasales@yongstandards.com China 11927 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Shijiazhuang Jianxin Biotechnology Co., LTD
+undefined+86-17692708569 liyingjian1997@gmail.com China 787 58

View Lastest Price from DL-NORPHENYLEPHRINE HYDROCHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DL-NORPHENYLEPHRINE HYDROCHLORIDE USP/EP/BP pictures 2021-08-12 DL-NORPHENYLEPHRINE HYDROCHLORIDE USP/EP/BP
4779-94-6
US $1.10 / g 1g 99.9% 100 Tons min Dideu Industries Group Limited
DL-NORPHENYLEPHRINE HYDROCHLORIDE pictures 2021-07-20 DL-NORPHENYLEPHRINE HYDROCHLORIDE
4779-94-6
US $1.00-1.00 / KG 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd
alpha-(aminomethyl)-3-hydroxy-benzenemethanohydrochloride alpha-aminomethyl-3-hydroxy-benzylalcohohydrochloride m-octopaminehydrochloride norfenefrin α-(AMinoMethyl)-3-hydroxybenzeneMethanol 3-(2-aMino-1-hydroxyethyl)phenol hydrochloride Phenylephrine Impurity A HCl (racemic Norphenylephrine HCl) Phenylephrine, Neosynephrine, Neophyrin, Mesaton (+/-)-NORPHENYLEPHRINE HYDROCHLORIDE, 98 % α-aminomethyl-3-hydroxybenzyl alcohol hydrochloride 1-(m-Hydroxyphenyl)-2-aminoethanol hydrochloride 2-Amino-1-(3-hydroxyphenyl)ethanol hydrochloride Benzenemethanol, a-(aminomethyl)-3-hydroxy-, hydrochloride (9CI) Benzyl alcohol, a-(aminomethyl)-m-hydroxy-, hydrochloride (6CI, 8CI) Coritat Depot-Novadral dl-Norfenefrine hydrochloride Energona Esbuphon Molycor R nofenefrine hydrochloride NSC 100733 NSC 297582 Stagural Tonolift Vingsal WV 569 α-Aminomethyl-4-hydroxybenzyl alcohol hydrochloride norphenephrinehydrochloride A-AMINOMETHYL-M-HYDROXYBENZYLALCOHOL HYDROCHLORIDE (+/-)-NORPHENYLEPHRINE HYDROCHLORIDE NORPHENYLEPHRINE HYDROCHLORIDE M-HYDROXYPHENYLAMINOETHANOL HYDROCHLORIDE TIMTEC-BB SBB000279 rac Norphenylephrine Hydrochloride (Phenylephrine Impurity A) Phenylephrine Impurity A HCl rac-Norphenylephrine hydrochloride Racemic Phenylephrine EP Impurity A HCl rac-Phenylephrine EP Impurity A HCl Phenylephrine Impurity A Etilefrine EP Impurity C Phenylephrine EP Impurity A Racemate Octopamine Impurity 12 Phenylephrine Hydrochloride Impurity A 3-(2-amino-1-hydroxyethyl)phenol:hydron:chloride Phenylephrine Impurity 16(Racemic Phenylephrine EP Impurity A HCl) Benzenemethanol, a-(aminomethyl)-3-hydroxy-,hydrochloride (1:1) DL-NORPHENYLEPHRINE HYDROCHLORIDE USP/EP/BP Noradrenaline (Norepinephrine) Impurity 51 (RS)-NORPHENYLEPHRINE HYDROCHLORIDE racemic Norphenylephrine HCl Norphenylephrine Hydrochloride (1473206) Phenylephrine EP Impurity A Racemate HCl Etilefrine Hydrochloride Impurity C as Hydrochloride Phenylephrine Hydrochloride Impurity A as Racemate Hydrochloride Phenylephrine Hydrochloride EP Impurity A as Racemate Hydrochloride Rac-Phenylephrine EP Impurity A HCl(Etilefrine EP Impurity C HCl) Etilefrine Hydrochloride EP Impurity C as Hydrochloride