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Megestrol acetate

Megestrol acetate
Megestrol acetate structure
CAS No.
595-33-5
Chemical Name:
Megestrol acetate
Synonyms
S4;MGA;Nia;5071;Megace;MGA-d3;Ovaban;Ovarid;bdh1298;Maygace
CBNumber:
CB9434253
Molecular Formula:
C24H32O4
Formula Weight:
384.51
MOL File:
595-33-5.mol

Megestrol acetate Properties

Melting point:
214°C
Boiling point:
431.17°C (rough estimate)
alpha 
D24 +5° (chloroform)
Density 
1.0474 (rough estimate)
refractive index 
11 ° (C=2, CHCl3)
storage temp. 
Refrigerator
solubility 
Practically insoluble in water, soluble in acetone, sparingly soluble in alcohol.
form 
neat
Merck 
14,5805
BRN 
1917291
CAS DataBase Reference
595-33-5(CAS DataBase Reference)
NIST Chemistry Reference
Megestrol acetate(595-33-5)
EPA Substance Registry System
Pregna-4,6-diene- 3,20-dione, 17-(acetyloxy)-6-methyl-(595-33-5)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H351-H373
Precautionary statements  P260-P280-P281
Hazard Codes  Xn
Risk Statements  40-48
Safety Statements  22-24/25
WGK Germany  3
RTECS  TU4075000
HS Code  29372390
Toxicity LD50 intravenous in mouse: 56mg/kg

Megestrol acetate price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M0513 Megestrol acetate analytical standard, for drug analysis 595-33-5 1g $109 2018-11-20 Buy
Sigma-Aldrich 1379106 Megestrol acetate United States Pharmacopeia (USP) Reference Standard 595-33-5 250mg $352.8 2018-11-20 Buy
TCI Chemical M1949 Megestrol Acetate >96.0%(HPLC) 595-33-5 1g $68 2018-11-22 Buy
TCI Chemical M1949 Megestrol Acetate >96.0%(HPLC) 595-33-5 5g $205 2018-11-22 Buy
Cayman Chemical 21749 Megestryl Acetate ≥98% 595-33-5 5g $192 2018-11-19 Buy

Megestrol acetate Chemical Properties,Uses,Production

Chemical Properties

Crystalline Solid

Uses

Progestogen;Progesterone receptor agonist

Uses

Orally active progestogen; formerly used in combinations as oral contraceptive

brand name

Megace (Bristol-Myers Squibb); Megace (Par).

General Description

Megestrol acetate, 17-hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate(Megace), is a progestin used primarily for the palliativemanagement of recurrent, inoperable, or metastatic endometrialor breast carcinoma. Megestrol acetate has also beenindicated for appetite enhancement in patients with AIDS.The biochemical basis for this use of megestrol is unclear.

Safety Profile

Suspected carcinogen with experimental carcinogenic and teratogenic data. Poison by intravenous route. Human reproductive effects bp ingestion and implant routes: effects on ovaries and fallopian tubes, menstrual cycle changes, and female fertility index changes. Mutation data reported. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes. An FDA proprietary drug used to treat endometriosis and breast cancer. A steroid.

Veterinary Drugs and Treatments

Megestrol acetate (Ovaban?—Schering) is approved by FDA for use in dogs only for the postponement of estrus and the alleviation of false pregnancy. In male dogs, it has been used for benign prostatic hypertrophy. It is used clinically for many dermatologic and behavior- related conditions, primarily in the cat. See the Dosage section for specific indications and dosages for both dogs and cats.
Megestrol acetate is indicated in humans for the palliative treatment of advanced carcinoma of the breast or endometrium.

Megestrol acetate Preparation Products And Raw materials

Raw materials

Preparation Products


Megestrol acetate Suppliers

Global( 269)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3194 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21671 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sale@mainchem.com CHINA 32447 55
PI & PI BIOTECH INC.
020-81716320
020-81716319 Sales@pipitech.com CHINA 2543 55
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 30001 58
Hebei Huanhao Biotechnology Co., Ltd.
86-18034554576 whatsapp +8618034554576
86-0311-83975816 grace@hbhuanhao.com CHINA 720 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 sales@jushengtech.com CHINA 28236 58
QUALITY CONTROL CHEMICALS INC.
(323) 306-3136
(626) 453-0409 orders@qcchemical.com United States 8407 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930501651
whatsapp: +8619930501651 breeduan@crovellbio.com CHINA 2294 58

View Lastest Price from Megestrol acetate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-10-22 Megestrol acetate
595-33-5
US $95.00 / KG 10g 99% 20tons Hebei shuoxi biotechnology co. LTD
2019-07-23 Megestrol acetate
595-33-5
US $1.00 / g 1g 99% 100 Ton/Tons per Month Cangzhou Wanyou New Material Technology Co.,Ltd
2018-12-18 Megestrol acetate
595-33-5
US $1.00 / kg 1kg 95%-99% 10kg career henan chemical co

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