MATRILYSIN
- CAS No.
- 141256-52-2
- Chemical Name:
- MATRILYSIN
- Synonyms
- MMP-7;PUMP-1;RHMMP-7;MMP7 HUMAN;MATRILYSIN;HUMAN MMP-7;MATRILYSIN-1;EC 3.4.24.23;RHMMP-7, ACTIVE;Pump-1 protease
- CBNumber:
- CB9439940
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01633460
- MOL File:
- Mol file
| storage temp. | -70°C |
|---|---|
| form | buffered aqueous solution |
| EWG's Food Scores | 1 |
| FDA UNII | P23XDW0WB7 |
SAFETY
Risk and Safety Statements
| Hazard Codes | B |
|---|---|
| WGK Germany | 3 |
| HS Code | 3504009000 |
MATRILYSIN price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M4565 | Matrix Metalloproteinase-7 human ~0.1?mg/mL, recombinant, expressed in E. coli, buffered aqueous solution | 141256-52-2 | 10μG | $519 | 2023-06-20 | Buy |
| Usbiological | 357383 | MMP-7 | 141256-52-2 | 48Tests | $588 | 2021-12-16 | Buy |
| Usbiological | 357382 | MMP-7 | 141256-52-2 | 48Tests | $588 | 2021-12-16 | Buy |
| Usbiological | 383723 | MMP-7 | 141256-52-2 | 96Tests | $669 | 2021-12-16 | Buy |
| Apolloscientific | BITP1337 | Recombinant Human Matrix Metalloproteinase-7 | 141256-52-2 | 5μg | $75 | 2021-12-16 | Buy |
MATRILYSIN Chemical Properties,Uses,Production
Uses
Matrix metalloproteinase-7 (MMP7) human has been used in in silico analysis of MMP-7 proteolysis of perlecan.
General Description
Matrix metalloproteinase-7 (MMP7) also referred to as matrilysin is encoded by the gene mapped to human chromosome 11q21-q22. MMP7 is a smallest member of MMP enzyme family and is highly expressed in cancer cells. MMP7 is exclusively released by epithelial cells.
Biochem/physiol Actions
Matrix metalloproteinase-7 (MMP-7) catalyzes the cleavage of extracellular matrix (ECM) proteins such as proteoglycans, fibronectin, entactin, laminin, collagen III/ IV/ V/ IX/ X/ XI, type I/ II/ IV/ V gelatins, and elastin. Matrix metalloproteinase-7 facilitates initial stages of tumor progression. Activated MMP7 plays a vital role in human colorectal cancer (CRC) liver metastases. Overexpression of MMP7 is observed in various human cancers, such as breast, lung, prostate, esophagus, stomach, endometrium, and ovarian carcinomas, as well as esophageal squamous cell carcinomas. Increased expression of MMP7 is also associated with pathogenesis of demyelinating multiple sclerosis (MS) lesions. Both in silico and in vitro studies show that MMP7 degrades glycosylated and basement membrane bound perlecan and plays a vital role in prostate cancer cell invasion.
MATRILYSIN Preparation Products And Raw materials
Raw materials
Preparation Products
MATRILYSIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 15926423062 | 422450190@qq.com | China | 10132 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 6633 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| AntibodySystem | 027-65279366 18162686757 | biolab-reagents@atagenix.com | China | 9784 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6106 | 58 |