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Xylenol structure
Chemical Name:
Molecular Formula:
Formula Weight:
MOL File:

Xylenol Properties

Melting point:
42.65°C (estimate)
Boiling point:
209.6°C (estimate)
0.9863 (estimate)
refractive index 
1.5321 (estimate)
Sweet tarry.
CAS DataBase Reference
1300-71-6(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances
EWG's Food Scores
EPA Substance Registry System
Dimethylphenol (1300-71-6)
  • Risk and Safety Statements
RIDADR  2261
HazardClass  6.1(a)
PackingGroup  II
Toxicity LDLo oral in man: 5gm/kg
NFPA 704
3 1

Xylenol Chemical Properties,Uses,Production

Chemical Properties

White, crystalline solid. Only slightly soluble in water; soluble in most organic solvents and caustic soda solution. Combustible.


Disinfectants, solvents, pharmaceuticals, insecticides and fungicides, plasticizers, rubber chemicals, additives to lubricants and gasolines, manufacture of polyphenylene oxide (2,6-isomer only), wetting agents, dyestuffs.

Production Methods

Xylenes are obtained mainly (80%) from petroleum reformate streams in the form of "mixed xylenes." A typical composition of this stream is about 18 percent p-xylene, 40 percent m-xylene, 22 percent o-xylene, and 20 percent ethylbenzene. The major chemical uses of xylene, however, require the pure isomers. The purification process involves a number of steps. First the a-xylene is separated from the other aromatics by distillation, with the meta and para isomers going overhead along with the ethylbenzene. p-Xylene can be recovered by either adsorption or crystallization processes. In the adsorption process, the stream is charged to a fixed bed of molecular sieves, and the selectively adsorbed p-xylene is recovered by washing the bed with solvent. Because the demand for p-xylene is far greater than that for m-xylene, the raffinate usually is isomerized to form more ofthe para isomer. Toluene may also be disproportionated to form equivalent amounts of benzene and xylenes without any ethylbenzene. Recently, this TOP process became more favorable. Today, it contributes to 18.5 percent of xylene production.
In 1999, the total demand for the xylenes (12.3 billion lb) was roughly comparable to that for toluene. The volume of 0-, m- and p-xylene were approximately 1.1 , 0.27, and 9.9 billion lb, respectively. The principal uses of the three xylene isomers are the production of terephthalic acid (or di-methyl terephthalate), phthalic anhydride, and isophthalic acid, respectively.

Health Hazard

Recommended Personal Protective Equipment: Organic canister mask; goggles and face shield; rubber gloves; other protective clothing to prevent contact with skin; Symptoms Following Exposure: Vapor irritates eyes, nose, and throat and readily absorbed through mucous membranes and lungs; producing general toxic symptoms (weakness, dizziness, headache, difficult breathing, twitching). Contact with skin causes temporary prickling and intense burning, then local anesthesia. Affected areas initially show white discoloration, wrinkling, and softening, then become red, then brown or black (signs of gangrene). Extensive burns may permit absorption of chemical to produce toxic symptoms described above. Ingestion causes irritation of mouth and stomach, nausea, abdominal pain, weakness, dizziness, headache, difficult breathing, and twitching; General Treatment for Exposure: Get medical attention at once following exposure to this compound. INHALATION: remove patient immediately to fresh air; irritation of nose or throat may be somewhat relieved by spraying or gargling with water-until all odor is gone; 100% oxygen inhalation is indicated for cyanosis or respiratory distress; keep patient warm, but not hot. EYES: flood with running water for 15 min.; if physician is not immediately available, continue irritation for another 15 min.; do not use oils or oily ointments unless ordered by physician. SKIN: wash affected areas with large quantities of water or soapy water until all odor is gone; then wash with alcohol or 20% glycerin solution and more water; keep patient warm, but not hot; cover chemical burns continuously with compresses wet with saturated solution of sodium thiosulphate; apply no salves or ointments for 24 hrs after injury. INGESTION: give large quantities of liquid (salt water, weak sodium bicarbonate solution, milk, or gruel) followed by demulcent such as raw egg white or corn starch paste; if profuse vomiting does not follow immediately, give a mild emetic (such as 1 tbsp. mustard in glass of water), or tickle back of throat. Repeat procedure until vomitus is free of the odor. Some demulcent should be left in stomach after vomiting. Keep patient comfortably warm; Toxicity by Inhalation (Threshold Limit Value): 45 ppm; Short-Term Exposure Limits: Data not available; Toxicity by Ingestion: Grade 2, oral LD50= 1,070 mg/kg (mouse); Late Toxicity: Damage to heart muscle, and changes in liver, kidney in rats; Vapor (Gas) Irritant Characteristics: Data not available; Liquid or Solid Irritant Characteristics: Data not available; Odor Threshold: Data not available.

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Safety Profile

A poison. When heated to decomposition it emits acrid smoke and irritating fumes. See also other xylenol entries.

Xylenol Preparation Products And Raw materials

Raw materials

Preparation Products

Xylenol Suppliers

Global( 78)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-66670886 China 20907 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 22607 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418697 China 3000 55
Hubei xin bonus chemical co. LTD
027-59338440 CHINA 23035 58
86-18523575427 CHINA 47498 58
career henan chemical co
13203830695 0086-371-86658258
0086-371-86658258 CHINA 29864 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418697 CHINA 37441 58
13588875226 86-571-88216897、88216896
86-571-88216895 CHINA 6469 58
ShenZhen Ipure Biology import and export company co.,ltd
18071025641 18071025641 CHINA 11336 58
Dideu Industries Group Limited
029-88380327 CHINA 30014 58

View Lastest Price from Xylenol manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2020-01-10 Xylenol
US $1.00 / KG 1KG 98% HPLC 10 tons/month Career Henan Chemical Co
2020-01-01 Xylenol
US $0.10 / KG 1KG 99.0% 1000 tons Shaanxi Dideu Medichem Co. Ltd

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