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Phenylmethylsulfonyl fluoride

Phenylmethylsulfonyl fluoride
Phenylmethylsulfonyl fluoride structure
CAS No.
329-98-6
Chemical Name:
Phenylmethylsulfonyl fluoride
Synonyms
PMSF;PMSF PLUS;PMSF, PMs-F;BCS ASSAY KIT;TOSYL FLUORIDE;Phenylmethanesulfony;BENZYLSULFONYL FLUORIDE;benzylsulphonylfluoride;PHENYLMETHANSULFOFLUORIDE;A-TOLUENESULFONYL FLUORIDE
CBNumber:
CB9454820
Molecular Formula:
C7H7FO2S
Formula Weight:
174.19
MOL File:
329-98-6.mol

Phenylmethylsulfonyl fluoride Properties

Melting point:
92-95 °C
Boiling point:
112 °C16 mm Hg(lit.)
Density 
0.797 g/mL at 20 °C
Flash point:
222 °F
storage temp. 
2-8°C
solubility 
dry solvents (ethanol, methanol, and 2-propanol): 200 mM Stock solution are stable for months at 4°C.
form 
Needles (May Agglomerate)
color 
White
Water Solubility 
hydrolysis
Sensitive 
Moisture Sensitive
Merck 
14,7542
BRN 
2088311
InChIKey
YBYRMVIVWMBXKQ-UHFFFAOYSA-N
CAS DataBase Reference
329-98-6(CAS DataBase Reference)
EPA Substance Registry System
Benzenemethanesulfonyl fluoride (329-98-6)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS02,GHS07,GHS05,GHS06
Signal word  Danger
Hazard statements  H301-H314-H225-H315-H319-H290-H318
Precautionary statements  P260h-P301+P310a-P501a-P234-P264-P270-P301+P330+P331+P310-P303+P361+P353+P310+P363-P390-P405-P406-P501-P260-P280-P301+P310+P330-P303+P361+P353-P304+P340+P310-P305+P351+P338+P310-P305+P351+P338-P310-P210-P337+P313-P403+P235
Hazard Codes  F,T,C
Risk Statements  11-34-25-23/24/25
Safety Statements  7-16-45-36/37/39-28A-26-27
RIDADR  UN 3261 8/PG 2
WGK Germany  3
RTECS  XT8050000
3-10-21
Hazard Note  Highly Toxic/Corrosive
TSCA  T
HazardClass  8
PackingGroup  III
HS Code  29241990
Toxicity LD50 (24 hr) in mice (mg/kg): 215 ±55 i.p. (Pinsky)

Phenylmethylsulfonyl fluoride price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 52332 Phenylmethylsulfonyl Fluoride 329-98-6 1gm $42.5 2019-12-02 Buy
Sigma-Aldrich 52332 Phenylmethylsulfonyl Fluoride 329-98-6 5gm $64.4 2019-12-02 Buy
TCI Chemical B1062 Benzylsulfonyl Fluoride >98.0%(GC) 329-98-6 5g $22 2019-12-02 Buy
TCI Chemical B1062 Benzylsulfonyl Fluoride >98.0%(GC) 329-98-6 25g $78 2019-12-02 Buy
Alfa Aesar B22146 alpha-Toluenesulfonyl fluoride, 99% 329-98-6 1g $21.8 2019-12-02 Buy

Phenylmethylsulfonyl fluoride Chemical Properties,Uses,Production

Chemical Properties

White to cream solid

Uses

PMSF is an irreversible serine/cysteine protease inhibitor

Uses

Phenylmethylsulfonyl fluoride is used as a Protease inhibitor such as Chymotrypsin, Trypsin and Thrombin as well as Acetylcholineesterase.

Uses

Standard protease inhibitor in biological research; in protein purification to prevent proteolytic degradation.

Definition

ChEBI: An acyl fluoride with phenylmethanesulfonyl as the acyl group.

Purification Methods

Purify PMSF by recrystallisation from *C6H6, pet ether or CHCl3/pet ether. [Davies & Dick J Chem Soc 483 1932, cf Tullock & Coffman J Org Chem 23 2016 1960.] It is a general protease inhibitor (specific for trypsin and chymotrypsin) and is a good substitute for diisopropylphosphoro floridate [Fahrney & Gould J Am Chem Soc 85 997 1963]. [Beilstein 11 III 331.]

Phenylmethylsulfonyl fluoride Preparation Products And Raw materials

Raw materials

Preparation Products


Phenylmethylsulfonyl fluoride Suppliers

Global( 226)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Yunbio Tech Co.,Ltd.
010-60605551
010-60605551 yunbiochem@126.com CHINA 256 58
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21686 58
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Mainchem Co., Ltd.
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+86-0592-6210733 sale@mainchem.com CHINA 32447 55
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career henan chemical co
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Haihang Industry Co.,Ltd
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Shandong chuangyingchemical Co., Ltd.
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View Lastest Price from Phenylmethylsulfonyl fluoride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-25 Phenylmethylsulfonyl fluoride
329-98-6
US $1044.00 / KG 1KG 99% 20kg career henan chemical co

Phenylmethylsulfonyl fluoride Spectrum


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