BTS
- CAS No.
- 1576-37-0
- Chemical Name:
- BTS
- Synonyms
- BTS;CLN3;Battenin;NSC 37123;N-Tosylbenzylamine;N-Benzyl-p-tosylaMide;LABOTEST-BB LT00786416;N-Tosylphenylmethanamine;N-Tosylbenzenemethaneamine;n-benzyl-p-toluenesulfonamid
- CBNumber:
- CB9457528
- Molecular Formula:
- C14H15NO2S
- Molecular Weight:
- 261.34
- MDL Number:
- MFCD00159328
- MOL File:
- 1576-37-0.mol
- MSDS File:
- SDS
| Melting point | 115 °C |
|---|---|
| Boiling point | 419.1±48.0 °C(Predicted) |
| Density | 1.204±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Dichloromethane, Ethyl Acetate (Slightly) |
| form | White crystalline solid |
| pka | 11.54±0.30(Predicted) |
| color | White to Off-White |
| Sensitive | Light Sensitive |
| CAS DataBase Reference | 1576-37-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| RTECS | XT5490000 | |||||||||
| HS Code | 2935.90.9500 | |||||||||
| Toxicity | rat,LD,oral,> 500mg/kg (500mg/kg),National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 41, 1953. | |||||||||
| NFPA 704 |
|
BTS price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 203895 | BTS A potent inhibitor of Ca | 1576-37-0 | 5mg | $172 | 2024-03-01 | Buy |
| TCI Chemical | B3082 | N-Benzyl-p-toluenesulfonamide >98.0%(HPLC)(N) | 1576-37-0 | 5g | $131 | 2024-03-01 | Buy |
| TCI Chemical | B3082 | N-Benzyl-p-toluenesulfonamide >98.0%(HPLC)(N) | 1576-37-0 | 25g | $394 | 2024-03-01 | Buy |
| Alfa Aesar | J64910 | N-Benzyl-p-toluenesulfonamide | 1576-37-0 | 5mg | $117.65 | 2024-03-01 | Buy |
| Alfa Aesar | J64910 | N-Benzyl-p-toluenesulfonamide | 1576-37-0 | 10mg | $212 | 2024-03-01 | Buy |
BTS Chemical Properties,Uses,Production
Description
BTS is an inhibitor of skeletal muscle myosin II ATPase activity that reduces the affinity of ADP-myosin for actin. It inhibits calcium-stimulated ATPase activity of rabbit muscle myosin subfragment 1 (S1) in an actin-independent manner with an IC50 value of approximately 5 μM. It is selective for calcium-stimulated myosin II over human platelet myosin II, kinesin, pyruvate kinase, and lactate dehydrogenase at 100 μM. BTS (2 μM) inhibits the activity of skeletal muscle myosin, reversibly reducing the sliding velocity of heavy meromyosin in a gliding-filament assay. It inhibits isometric calcium-activated tension in isolated fast-twitch rabbit psoas muscle fibers (IC50 = ~3 μM) but not in isolated slow-twitch rat trabeculae and papillary cardiac muscle. BTS is also an intermediate in the synthesis of sulfonamides.
Chemical Properties
White Solid
Uses
A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin interaction with F-actin. Does not affect platelet myosin II
Uses
A potent inhibitor of calcium-stimulated myosin S1 ATPase
Definition
ChEBI: 4-methyl-N-(phenylmethyl)benzenesulfonamide is a sulfonamide.
Synthesis Reference(s)
The Journal of Organic Chemistry, 28, p. 592, 1963 DOI: 10.1021/jo01037a523
Biological Activity
Selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC 50 ~ 5 mM). Reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle.
storage
Desiccate at RT
BTS Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7786 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Hebei Duling International Trade Co. LTD | +8618032673083 | sales05@hbduling.cn | China | 15745 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
View Lastest Price from BTS manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-01-14 | N-Benzyl-p-toluenesulfonaMide
1576-37-0
|
US $10.00-0.80 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2019-12-23 | BTS
1576-37-0
|
US $1.00 / KG | 1KG | 98% HPCL | 10t | Career Henan Chemical Co |
-
- N-Benzyl-p-toluenesulfonaMide
1576-37-0
- US $10.00-0.80 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- BTS
1576-37-0
- US $1.00 / KG
- 98% HPCL
- Career Henan Chemical Co
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