IONOMYCIN CALCIUM SALT
- CAS No.
- 56092-82-1
- Chemical Name:
- IONOMYCIN CALCIUM SALT
- Synonyms
- ATCC 31005;Ionomycin,Ion;IONOMYCIN (CA);SQ23377 calcium;ionomycin calcium;IONOMYCIN CA-SALT;Calcium ionomycin.;Ionomycin Ca2+ salt;IONOMYCIN CALCIUM SALT;IONOMYCIN CALCIUM SALT 1MG
- CBNumber:
- CB9458893
- Molecular Formula:
- C41H70CaO9
- Molecular Weight:
- 747.07
- MDL Number:
- MFCD00083634
- MOL File:
- 56092-82-1.mol
- MSDS File:
- SDS
| Melting point | 205-206 C |
|---|---|
| Flash point | 87 °C |
| storage temp. | −20°C |
| solubility | Soluble in DMSO (10mg/ml). Also soluble in ethanol or methanol |
| form | White to off-white solid |
| color | white to off-white |
| Sensitive | Light Sensitive |
| BRN | 1416163 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months. |
IONOMYCIN CALCIUM SALT price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | I0634 | Ionomycin calcium salt from Streptomyces conglobatus powder, ≥98% (HPLC) | 56092-82-1 | 1mg | $163 | 2024-03-01 | Buy |
| Sigma-Aldrich | I0634 | Ionomycin calcium salt from Streptomyces conglobatus powder, ≥98% (HPLC) | 56092-82-1 | 5mg | $711 | 2024-03-01 | Buy |
| Sigma-Aldrich | 407952 | Ionomycin, Calcium Salt, Streptomyces conglobatus - CAS 56092-82-1 - Calbiochem Ionomycin, Calcium Salt, Streptomyces conglobatus, CAS 56092-82-1, is useful in cell activation experiments when calcium dose-response data are not required. | 56092-82-1 | 5mg | $470 | 2022-05-15 | Buy |
| Alfa Aesar | J67343 | Ionomycin calcium salt, 1 mg/ml in methanol, sterile-filtered | 56092-82-1 | 1ml | $423 | 2024-03-01 | Buy |
| Alfa Aesar | J60628 | Ionomycin calcium salt, 99% | 56092-82-1 | 5mg | $193 | 2023-06-20 | Buy |
IONOMYCIN CALCIUM SALT Chemical Properties,Uses,Production
Description
Ionomycin is a calcium ionophore originally isolated from S. conglobatus. It induces intracellular calcium mobilization in X. laevis oocytes when used at a concentration of 5 μM. Ionomycin (5 μM) induces the formation of neutrophil extracellular traps (NETs) in isolated human neutrophils. Ionomycin in combination with phorbol 12-myristate 13-acetate (PMA; ) has commonly been used to induce the proliferation and activation of T cells, as well as to stimulate cytokine production in macrophages, in vitro.
Chemical Properties
Powder
Uses
Ionomycin is more effectivethan A23187 as a Ca++ionophore; Ionomycin is used in research on Ca++ transport across biological membranes; Ionomycin induces apoptotic degeneration of embryonic cortical neurons.
Uses
Ionomycin calcium salt is used as a polyether antibiotic and apoptotic degeneration inducer. Ionomycin induces apoptotic degeneration of embryonic cortical neurons and cell cycle arrest at G1 phase. It is more effective than A23187 (sc-3591) and provides a useful tool for increasing intracellular Ca2+ concentration.
General Description
Useful in cell activation experiments when calcium dose-response data are not required. Also available as a 10 mM solution in DMSO (Cat. No. 407953).
Biological Activity
Calcium ionophore; more specific than A23187 (5-(Methylamino)-2-[[2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)-ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-4-benzoxazolecarboxylic acid ).
Biochem/physiol Actions
Product does not compete with ATP.
storage
-20°C
References
Liu et al. (1978), Ionomycin, a new polyether antibiotic; J. Antibiot., 31 815 Liu and Hermann et al. (1978), Characterization of ionomycin as a calcium ionophore; J. Biol.Chem, 253 5892
IONOMYCIN CALCIUM SALT Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
| HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3465 | 58 |
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
View Lastest Price from IONOMYCIN CALCIUM SALT manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-26 | IONOMYCIN CALCIUM SALT
56092-82-1
|
US $1.00 / g | 1g | ≥98% | g/kg/Ton | Career Henan Chemical Co |
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- IONOMYCIN CALCIUM SALT
56092-82-1
- US $1.00 / g
- ≥98%
- Career Henan Chemical Co