(S)-1-Boc-3-methylpiperazine
- CAS No.
- 147081-29-6
- Chemical Name:
- (S)-1-Boc-3-methylpiperazine
- Synonyms
- tert-butyl (S)-3-methylpiperazine-1-carboxylate;(S)-1-BOC-3-METHYLPIPERAZINE;(S)-TERT-BUTYL 3-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-4-Boc-2-methylpiperazine;4-HYDROXY-7-METHOXYQUINOLINE-2-CARBOXYLIC ACID;4-Hydroxy-7-methoxy-2-quinolinecarboxylic acid;CPD2809-SM;(3S)-3-MethyL;(S)-4-N-BOC-2-METHYL;Sotorasib Impurity 2
- CBNumber:
- CB9458934
- Molecular Formula:
- C10H20N2O2
- Molecular Weight:
- 200.28
- MDL Number:
- MFCD02683204
- MOL File:
- 147081-29-6.mol
- MSDS File:
- SDS
Melting point | 40-45 °C |
---|---|
alpha | -16 º (c=1 in dioxane) |
Boiling point | 268.7±15.0 °C(Predicted) |
Density | 0.997±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
pka | 8.52±0.40(Predicted) |
form | Crystalline Powder |
color | White to yellow |
optical activity | [α]/D -16±2°, c = 1 in dioxane |
Sensitive | Air Sensitive |
InChI | InChI=1S/C10H20N2O2/c1-8-7-12(6-5-11-8)9(13)14-10(2,3)4/h8,11H,5-7H2,1-4H3/t8-/m0/s1 |
InChIKey | FMLPQHJYUZTHQS-QMMMGPOBSA-N |
SMILES | N1(C(OC(C)(C)C)=O)CCN[C@@H](C)C1 |
CAS DataBase Reference | 147081-29-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05,GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H315-H318-H335 | |||||||||
Precautionary statements | P280-P302+P352-P305+P351+P338+P310 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 37/38-41-34 | |||||||||
Safety Statements | 26-39-45-36/37/39 | |||||||||
RIDADR | 3259 | |||||||||
WGK Germany | 3 | |||||||||
F | 10-34 | |||||||||
HS Code | 29335990 | |||||||||
NFPA 704 |
|
(S)-1-Boc-3-methylpiperazine price More Price(55)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 63207 | (S)-1-Boc-3-methylpiperazine ≥98% | 147081-29-6 | 1g | $21.9 | 2024-03-01 | Buy |
Sigma-Aldrich | 63207 | (S)-1-Boc-3-methylpiperazine ≥98% | 147081-29-6 | 5G | $65.4 | 2024-03-01 | Buy |
Alfa Aesar | H27534 | (S)-(-)-1-Boc-3-methylpiperazine, 98% | 147081-29-6 | 1g | $64.65 | 2024-03-01 | Buy |
Alfa Aesar | H27534 | (S)-(-)-1-Boc-3-methylpiperazine, 98% | 147081-29-6 | 5g | $256 | 2024-03-01 | Buy |
TRC | B656830 | (S)-4-Boc-2-methylpiperazine | 147081-29-6 | 25g | $305 | 2021-12-16 | Buy |
(S)-1-Boc-3-methylpiperazine Chemical Properties,Uses,Production
Description
(S)-1-Boc-3-methylpiperazine is a hydrophobic compound that is structurally modified from the tetracyclic family of drugs. It has been shown to inhibit tumor cell growth by binding to the oncogene, KRASG12C, and downregulating its expression. This compound also inhibits cancer cell growth through the inhibition of the PI3K/AKT signaling pathway. The pharmacological effects of (S)-1-Boc-3-methylpiperazine are dependent on its ability to bind with high affinity to KRASG12C and inhibit its activity.
Chemical Properties
colorless to yellow liquid
Uses
Reactant involved in the synthesis of biologically activy molecules including:
- CCR5 antagonists with anti-HIV-1 activity
- Opioid receptor antagonists
- Human growth hormone secretagogue receptor antagonists for treatment of obesity
- Fatty acid oxidation inhibitors
Uses
(S)-4-Boc-2-methylpiperazine ((S)-1-Boc-3-methylpiperazine) is a reagent used in the synthesis of benzamide peptidomimetic as non-ATP competitive inihbitors.
Uses
Laboratory chemicals, Manufacture of substances.
(S)-1-Boc-3-methylpiperazine Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Boc Chemical Co., Ltd. | 021-34975602; +8618721111801 | shangli@bocchem.com | China | 138 | 58 |
AstaTech(Chengdu) Biopharmaceutical Corp. | +86-02882666559 +86-15884417729 | gjpu@astatech.com.cn | China | 308 | 58 |
Golden Pharma Co., Limited | +undefined18958062155 | sales@zjgoldpharm.com | China | 5905 | 58 |
Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 +8618018249389 | sales@anikare.com | China | 9259 | 58 |
Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 7193 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20293 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Chembon Pharmaceutical Co., Ltd. | +86-28-8425-2981 | CHINA | 724 | 55 | |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10311 | 58 |
View Lastest Price from (S)-1-Boc-3-methylpiperazine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-12 | (S)-4-N-Boc-2-methylpiperazine
147081-29-6
|
US $37.00-788.00 / g | 10g | 0.99 | 25kg | Shanghai UCHEM Inc. | ||
2024-05-20 | (S)-4-N-Boc-2-methylpiperazine
147081-29-6
|
US $0.00-0.00 / KG | 0.5KG | 99.0%GC | 1-5tons/year | AstaTech(Chengdu) Biopharmaceutical Corp. | ||
2024-04-15 | (S)-1-Boc-3-methylpiperazine
147081-29-6
|
US $5.00-0.10 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd |
- (S)-4-N-Boc-2-methylpiperazine
147081-29-6
- US $37.00-788.00 / g
- 0.99
- Shanghai UCHEM Inc.
- (S)-4-N-Boc-2-methylpiperazine
147081-29-6
- US $0.00-0.00 / KG
- 99.0%GC
- AstaTech(Chengdu) Biopharmaceutical Corp.
- (S)-1-Boc-3-methylpiperazine
147081-29-6
- US $5.00-0.10 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
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