ChemicalBook >> CAS DataBase List >>LIT-927
LIT-927
- CAS No.
- 2172879-52-4
- Chemical Name:
- LIT-927
- Synonyms
- LIT-927;CS-2869;2(1H)-Pyrimidinone, 4-(4-chlorophenyl)-6-(4-hydroxy-3-methoxyphenyl)-
- CBNumber:
- CB94668137
- Molecular Formula:
- C17H13ClN2O3
- Molecular Weight:
- 328.75
- MDL Number:
- MFCD31726172
- MOL File:
- 2172879-52-4.mol
Last updated:2023-05-21 10:59:17
LIT-927 price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML2893 | LIT-927 ≥98% (HPLC) | 2172879-52-4 | 5MG | $94.2 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML2893 | LIT-927 ≥98% (HPLC) | 2172879-52-4 | 25MG | $306 | 2024-03-01 | Buy |
| Cayman Chemical | 28436 | LIT-927 | 2172879-52-4 | 5mg | $93 | 2024-03-01 | Buy |
| Cayman Chemical | 28436 | LIT-927 | 2172879-52-4 | 50mg | $547 | 2024-03-01 | Buy |
| Cayman Chemical | 28436 | LIT-927 | 2172879-52-4 | 10mg | $146 | 2024-03-01 | Buy |
LIT-927 Chemical Properties,Uses,Production
Biochem/physiol Actions
LIT-927 is an orally active CXCL12 (SDF1) neutraligand (Kd = 267) that selectively neutralizes CXCL12, but not CCL17, CCL22, CCL5, or CCL2 activity in cultures (10 μM LIT-927 against 5 nM chemokine-induced calcium mobilization). LIT-927 reduces eosinophil recruitment in a murine allergic airway hypereosinophilia model in vivo (330 nmol/kg intranasal, 350 nmol/kg ip. or 1400 μmol/kg po.), offering greatly improved oral activity and solubility than Chalcone-4, and exhibiting little side-effects when compared with dexamethasone or CXCR4 antagonist AMD3100.
LIT-927 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 44)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Chemia Biotechnology（Shanghai） Co., Ltd | +8613816753574 | info@chemia-pharm.com | CHINA | 311 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4121 | 55 | |
| Shanghaizehan biopharma technology co., Ltd. | 021-61350663 13052117465 | sales@zehanbiopharma.com | China | 994 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
CS-2869
LIT-927
2(1H)-Pyrimidinone, 4-(4-chlorophenyl)-6-(4-hydroxy-3-methoxyphenyl)-
2172879-52-4
API