Anti-VinculinFITC antibody, Mouse monoclonal
- CAS No.
- Chemical Name:
- Anti-VinculinFITC antibody, Mouse monoclonal
- Synonyms
- Anti-VinculinFITC antibody, Mouse monoclonal
- CBNumber:
- CB94669806
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-VinculinFITC antibody, Mouse monoclonal Chemical Properties,Uses,Production
Uses
Monoclonal Anti-Vinculin-FITC antibody is suitable for immunofluorescence staining of fibroblasts cells to study the effects of nanofiber spatial organization on cell behaviors. It is also suitable for direct immunofluorescence at a dilution of 1:50 using methanol/acetone fixed cultured bovine MDBK cells.
Biochem/physiol Actions
Vinculin is a cytoskeletal protein with molecular mass of ~116 kDa. Vinculin is closely associated with adhesive membrane areas, such as focal contacts, podosomes, or intercellular junctions of the zonula adherens type. It acts as a mediator in interactions of integrins and the actin cytoskeleton. It forms a bridge between integrins, receptors for ECM molecules on the cell surface and the F-actin cytoskeleton. It is associated with talin and α-actinin which directly connects with integrins. It has ability to bind α-catenin as well as the vasodilator stimulated phosphoprotein (VASP) in focal contact assembly.
Anti-VinculinFITC antibody, Mouse monoclonal Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-VinculinFITC antibody, Mouse monoclonal Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |