ChemicalBook >> CAS DataBase List >>Methylprednisolone hemisuccinate
Methylprednisolone hemisuccinate
- CAS No.
- 2921-57-5
- Chemical Name:
- Methylprednisolone hemisuccinate
- Synonyms
- Methylprednisolone 21-Hemisuccinate;6α-Methylprednisolone 21-HeMisuccinate;6α-Methylprednisolone 21-HeMisuccinate;Methylprednisolone hydrogen succinate CRS;drogensuccinate);(6-alpha,11-beta)-yl;Methylprednisolone, Powder;methylprednisolonesuccinate;Methylprednisolone sucsinate;Methylprednisolone Impurity 15
- CBNumber:
- CB9478132
- Molecular Formula:
- C26H34O8
- Molecular Weight:
- 474.54
- MDL Number:
- MFCD00271782
- MOL File:
- 2921-57-5.mol
- MSDS File:
- SDS
Last updated:2023-09-19 17:22:06
| Melting point | >230°C (dec.) |
|---|---|
| Boiling point | 689.6±55.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, slightly soluble in acetone and in anhydrous ethanol. It dissolves in dilute solutions of alkali hydroxides. |
| pka | 4.29±0.17(Predicted) |
| color | White to Off-White |
| LogP | 2.69 |
| CAS DataBase Reference | 2921-57-5(CAS DataBase Reference) |
| FDA UNII | 5GMR90S4KN |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H360FD-H373 |
| Precautionary statements | P202-P260-P280-P308+P313-P405-P501 |
| HS Code | 2937290000 |
Methylprednisolone hemisuccinate price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 1437009 | Methylprednisolone hemisuccinate United States Pharmacopeia (USP) Reference Standard | 2921-57-5 | 250mg | $436 | 2024-03-01 | Buy |
| Cayman Chemical | 11800 | 6α-Methylprednisolone 21-hemisuccinate ≥98% | 2921-57-5 | 10mg | $25 | 2024-03-01 | Buy |
| Cayman Chemical | 11800 | 6α-Methylprednisolone 21-hemisuccinate ≥98% | 2921-57-5 | 25mg | $57 | 2024-03-01 | Buy |
| Sigma-Aldrich | Y0001759 | Methylprednisolone hydrogen succinate for peak identification European Pharmacopoeia (EP) Reference Standard | 2921-57-5 | y0001759 | $150 | 2024-03-01 | Buy |
| Sigma-Aldrich | M1755220 | Methylprednisolone hydrogen succinate for performance test European Pharmacopoeia (EP) Reference Standard | 2921-57-5 | m1755220 | $60 | 2024-03-01 | Buy |
Methylprednisolone hemisuccinate Chemical Properties,Uses,Production
Description
Methylprednisolone hemisuccinate is a glucocorticoid used to treat severe allergic reactions, asthma, autoimmune diseases, blood disorders, gastrointestinal disorders, and endocrine disorders, among others.
Synthesis
Add 6L of dimethyl sulfoxide and 1kg of succinic anhydride in the reaction kettle, stir and dissolve at 25°C, add 0.8L of triethylamine, and stir for 10 minutes; add 1kg of methylprednisolone again, react at 30°C for 3 hours, add 10% hydrochloric acid water Terminate the reaction, separate 40 L of water, and stir for 30 minutes; filter and wash with water to obtain the crude product; the crude product is dissolved in 30 times of methanol temperature, and activated carbon is decolorized to obtain methylprednisolone succinate; the yield is 119%, and the content is 99.3%.
Chemical Properties
White or almost white, hygroscopic powder.
Uses
Glucocorticoid.
Uses
6α-Methylprednisolone 21-Hemisuccinate is a derivative of methylprednisolone (M325934), a glucocorticoid and a anti-inflammatory drug used to treat central nervous system disorders such as multiple sclerosis. 6α-Methylprednisolone 21-Hemisuccinate was examined for potential therapeutic efficacy in a model of neuroinflammation in rats with acute autoimmune encephalomyelitis.
Definition
ChEBI: Methylprednisolone succinate is a corticosteroid hormone and a hemisuccinate.
brand name
A-Methapred (Abbott); A-Methapred (Hospira); Solu-Medrol (Pharmacia & Upjohn).
Methylprednisolone hemisuccinate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 198)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12453 | 58 |
| Changzhou Rokechem Technology Co., Ltd. | 18758118018 | sales001@rokechem.com | China | 255 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81148696 +8615536356810 | 1047@dideu.com | China | 3527 | 58 |
View Lastest Price from Methylprednisolone hemisuccinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-19 | Methylprednisolone Hemisuccinate
2921-57-5
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-06-27 | Methylprednisolone sodium hemisuccinate
2921-57-5
|
US $0.00-0.00 / Kg | 1Kg | 99%; CP/EP/USP | 1-10000kgs | Changzhou Rokechem Technology Co., Ltd. | |
 |
2023-05-20 | Methylprednisolone Hemisuccinate
2921-57-5
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
-
- Methylprednisolone Hemisuccinate
2921-57-5
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- Methylprednisolone sodium hemisuccinate
2921-57-5
- US $0.00-0.00 / Kg
- 99%; CP/EP/USP
- Changzhou Rokechem Technology Co., Ltd.
-
- Methylprednisolone Hemisuccinate
2921-57-5
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
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2921-57-5
264368-56-0
C26H34O8
Steroid and Hormone
Steroids