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Methyl cyanoacetate

Description
Methyl cyanoacetate
Methyl cyanoacetate structure
CAS No.
105-34-0
Chemical Name:
Methyl cyanoacetate
Synonyms
MCYA;usafkf-22;USAF kf-22;Methylcyanacetat;MetthylCyanoacetate;METHYL CYANOACETATE;methyl2-cyanoacetate;methylcyanoethanoate;Methyl 2-cyanoacetate;Methyl cyanoethanoate
CBNumber:
CB9485583
Molecular Formula:
C4H5NO2
Formula Weight:
99.09
MOL File:
105-34-0.mol

Methyl cyanoacetate Properties

Melting point:
-13 °C
Boiling point:
204-207 °C(lit.)
Density 
1.123 g/mL at 25 °C(lit.)
vapor density 
3.41 (vs air)
vapor pressure 
0.2 mm Hg ( 20 °C)
refractive index 
n20/D 1.417(lit.)
Flash point:
>230 °F
storage temp. 
Store below +30°C.
solubility 
54g/l
form 
Liquid
color 
Clear colorless to very slightly yellow
Water Solubility 
54 g/L (20 ºC)
Sensitive 
Light Sensitive
BRN 
773945
CAS DataBase Reference
105-34-0(CAS DataBase Reference)
NIST Chemistry Reference
Acetic acid, cyano-, methyl ester(105-34-0)
EPA Substance Registry System
Acetic acid, cyano-, methyl ester(105-34-0)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi
Safety Statements  24/25
RIDADR  3276
WGK Germany  1
RTECS  AG4375000
Hazard Note  Irritant
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  29269095
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Methyl cyanoacetate price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 108421 Methyl cyanoacetate 99% 105-34-0 25g $25.2 2018-11-13 Buy
Sigma-Aldrich 108421 Methyl cyanoacetate 99% 105-34-0 2kg $147 2018-11-13 Buy
TCI Chemical C0442 Methyl Cyanoacetate >99.0%(GC) 105-34-0 25mL $23 2018-11-22 Buy
TCI Chemical C0442 Methyl Cyanoacetate >99.0%(GC) 105-34-0 500mL $48 2018-11-22 Buy
Alfa Aesar A15555 Methyl cyanoacetate, 99% 105-34-0 250g $28.7 2018-11-13 Buy

Methyl cyanoacetate Chemical Properties,Uses,Production

Description

Methyl cyanoacetate is the intermediate product in pharmaceutical organic synthesis as well as in the synthesis of some biologically active compounds used in agriculture. It may be used in the synthesis of various 1,2,5-tricarbonyl compounds. It is often used as a nucleophile in the electrochemical oxidation of catechols. Methyl Cyanoacetate is also a reagent in the synthesis of Methyl 2-Amino-4-trifluoromethylthiophene-3-carboxylate; a compound used in the synthesis of DPP-IV inhibitors for treating type-2 diabetes. In addition, it is an intermediate in the preparation of α-cyanoacrylate, malononitrile, and 1,1-cyclohexanediacetic acid dyes. It is used as UV absorber or stabilizer, intermediate for pharmaceuticals. It may be used in the synthesis of various 1,2,5-tricarbonyl compounds.

Chemical Properties

clear colorless to very slighlty yellow liquid

Uses

pharmaceutical intermediate

Purification Methods

Purify the ester by shaking with 10% Na2CO3 solution, wash well with water, dry with anhydrous Na2SO4, and distil it. [Beilstein 2 H 584, 2 I 253, 2 II 530, 2 III 1628, 2 IV 1889.]

Methyl cyanoacetate Preparation Products And Raw materials

Raw materials

Preparation Products


Methyl cyanoacetate Suppliers

Global( 257)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21930 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555
+86-021-57951555 jack.li@time-chemicals.com CHINA 1367 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
Hebei Chisure Biotechnology Co., Ltd.
+8613091036086; +8613292890173
+8613292893290 sandy@speedgainpharma.com; luna@speedgainpharma.com CHINA 1019 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20516 58
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23982 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20094 58
Jinan Finer Chemical Co., Ltd
+86-531-88989536
+86-531-88989539 sales@finerchem.com CHINA 939 58

View Lastest Price from Methyl cyanoacetate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Methyl cyanoacetate
105-34-0
US $1.00 / KG 1G 98% 100KG career henan chemical co

Methyl cyanoacetate Spectrum


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