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8-M-PDOT

8-M-PDOT Structure
8-M-PDOT structure
CAS No.
134865-70-6
Chemical Name:
8-M-PDOT
Synonyms
AH 002;8-M-PDOT;8 M PDOT,8MPDOT;8-METHOXY-2-PROPIONAMIDOTETRALIN;Propanamide, N-(1,2,3,4-tetrahydro-8-methoxy-2-naphthalenyl)-
CBNumber:
CB9487996
Molecular Formula:
C14H19NO2
Molecular Weight:
233.31
MDL Number:
MFCD00901636
MOL File:
134865-70-6.mol
Last updated:2023-05-18 11:31:11
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8-M-PDOT Properties

Boiling point 447.8±45.0 °C(Predicted)
Density 1.09±0.1 g/cm3(Predicted)
storage temp. Store at RT
solubility Soluble to 50 mM in ethanol and to 100 mM in DMSO
form Powder
pka 15.87±0.20(Predicted)

8-M-PDOT price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 29521 8-M-PDOT 134865-70-6 5mg $82 2024-03-01 Buy
Cayman Chemical 29521 8-M-PDOT 134865-70-6 10mg $138 2024-03-01 Buy
Cayman Chemical 29521 8-M-PDOT 134865-70-6 25mg $324 2024-03-01 Buy
Cayman Chemical 29521 8-M-PDOT 134865-70-6 50mg $606 2024-03-01 Buy
Tocris 1035 8-M-PDOT ≥99%(HPLC) 134865-70-6 50 $504 2021-12-16 Buy
Product number Packaging Price Buy
29521 5mg $82 Buy
29521 10mg $138 Buy
29521 25mg $324 Buy
29521 50mg $606 Buy
1035 50 $504 Buy

8-M-PDOT Chemical Properties,Uses,Production

Description

8-M-PDOT is a melatonin receptor 2 (MT2) agonist (Ki = 1.12 nM). It is 5.2-fold selective for MT2 over MT1 receptors in a radioligand binding assay. Striatal microinfusion of 8-M-PDOT (10 μg/μl) increases the percentage of time spent in the open arms of the elevated plus maze, indicating anxiolytic-like activity, in a rat model of rotenone-induced Parkinson''s disease.

Uses

AH 002 is a selective melatonin receptor agonist.

Biological Activity

Melatonin receptor agonist, 20-fold selective for the MT 2 (vs MT 1 ) subtype. At human recombinant MT 1 and MT 2 receptors, displays pK i values of 8.23 and 8.95 respectively.

8-M-PDOT Preparation Products And Raw materials

Raw materials

Preparation Products

8-M-PDOT Suppliers

Global( 29)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223 psaitong@jm-bio.com China 29834 58
Shanghai Universal Biotech Co.,Ltd 18768175414 gaojun@univ-bio.com China 24998 58
Kaifeng Mingren Pharmaceutical Co.,LTD 0371-65741762 sales@hasunny.com China 2380 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
EMMX Biotechnology LLC 60
Shanghai EFE Biological Technology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Shanghai Universal Biotech Co.,Ltd 58
Kaifeng Mingren Pharmaceutical Co.,LTD 58
TargetMol Chemicals Inc. 58

134865-70-6(8-M-PDOT)Related Search:

1-(2-METHOXY-PHENYL)-2-BUTANAMINE 2-Amtt 8-METHOXY-2-AMINOTETRALIN 8-M-PDOT Methoxyphenamine
8-METHOXY-2-PROPIONAMIDOTETRALIN 8-M-PDOT AH 002 8 M PDOT,8MPDOT Propanamide, N-(1,2,3,4-tetrahydro-8-methoxy-2-naphthalenyl)- 134865-70-6