DEOXYCHOLIC-2,2,4,4-D4 ACID
- CAS No.
- 112076-61-6
- Chemical Name:
- DEOXYCHOLIC-2,2,4,4-D4 ACID
- Synonyms
- Deoxycholic acid-D;Deoxycholic-d4 Acid;D4-Deoxycholic Acid;2H4]-Deoxycholic acid;DEOXYCHOLIC-2,2,4,4-D4 ACID;Deoxycholic acid-2,2,4,4-d4;Deoxycholic Acid-[d4] (Solution);Deoxycholic Acid-[d4] in Methanol;Deoxycholic acid (2,2,4,4-D?, 98%);Deoxycholic Acid-d4 MaxSpec? Standard
- CBNumber:
- CB9491841
- Molecular Formula:
- C24H40O4
- Molecular Weight:
- 392.58
- MDL Number:
- MFCD00209707
- MOL File:
- 112076-61-6.mol
| Product description | Number | Pack Size | Price |
| Deoxycholic Acid-d4 ≥95% | 20851 | 1mg | $62 |
| Deoxycholic Acid-d4 ≥95% | 20851 | 5mg | $270 |
| Deoxycholic Acid-d4 ≥95% | 20851 | 10mg | $477 |
| DEOXYCHOLIC ACID-2,2,4,4-D4 95.00% | RDL0006065 | 50MG | $903.5 |
| DEOXYCHOLIC ACID-2,2,4,4-D4 95.00% | RDL0006065 | 100MG | $1146.05 |
| Melting point | 171-174 °C |
|---|---|
| Flash point | 9℃ |
| storage temp. | -20°C |
| solubility | DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| InChIKey | KXGVEGMKQFWNSR-FCSCGBJGSA-N |
| SMILES | [H][C@@]12[C@]([C@](CC([2H])([2H])[C@@H](O)C3([2H])[2H])(C)[C@]3([H])CC2)([H])C[C@H](O)[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(O)=O |
| UNSPSC Code | 51113400 |
| NACRES | NA.12 |
| CAS Number Unlabeled | 83-44-3 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS02,GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H301+H311+H331-H370 | |||||||||
| Precautionary statements | P210-P260-P280-P301+P310+P330-P308+P311-P403+P233 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| WGK Germany | 3 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| NFPA 704 |
|
DEOXYCHOLIC-2,2,4,4-D4 ACID price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 20851 | Deoxycholic Acid-d4 ≥95% | 112076-61-6 | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 20851 | Deoxycholic Acid-d4 ≥95% | 112076-61-6 | 5mg | $270 | 2024-03-01 | Buy |
| Cayman Chemical | 20851 | Deoxycholic Acid-d4 ≥95% | 112076-61-6 | 10mg | $477 | 2024-03-01 | Buy |
| American Custom Chemicals Corporation | RDL0006065 | DEOXYCHOLIC ACID-2,2,4,4-D4 95.00% | 112076-61-6 | 50MG | $903.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0006065 | DEOXYCHOLIC ACID-2,2,4,4-D4 95.00% | 112076-61-6 | 100MG | $1146.05 | 2021-12-16 | Buy |
DEOXYCHOLIC-2,2,4,4-D4 ACID Chemical Properties,Uses,Production
Description
Deoxycholic acid-d4 (DCA-d4) is intended for use as an internal standard for the quantification of DCA (Item Nos. 20756 | 18231) by GC- or LC-MS. DCA is a secondary bile acid that is formed via microbial transformation of cholic acid in the colon. It can be conjugated to glycine or taurine to produce glycodeoxycholic acid (GDCA; ) or taurodeoxycholic acid (TDCA; ), respectively, in hepatocytes. DCA (0.2% v/v) inhibits spore germination induced by taurocholic acid (TCA; ) in seven C. difficile strains, as well as inhibits growth and decreases the cytotoxicity of C. difficile culture supernatants to Vero cells when used at a concentration of 0.02% v/v. It inhibits ionizing radiation-induced p53-dependent transcription in a reporter assay using HCT116 cells when used at a concentration of 200 μM. Fecal and intestinal tissue levels of DCA are increased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet. Increased serum DCA levels have been found in patients with colorectal cancer.
Uses
Deoxycholic-2,2,4,4-d4 Acid (CAS# 112076-61-6) is a useful isotopically labeled research compound.
Definition
ChEBI: Deoxycholic acid-2,2,4,4-d4 is a deuterated compound and a deoxycholic acid.
References
[1] RAJANI THANISSERY Casey M T Jenessa A Winston. Inhibition of spore germination, growth, and toxin activity of clinically relevant C. difficile strains by gut microbiota derived secondary bile acids[J]. Anaerobe, 2017, 45: Pages 86-100. DOI: 10.1016/j.anaerobe.2017.03.004
[2] D. QIAO. Deoxycholic acid suppresses p53 by stimulating proteasome-mediated p53 protein degradation.[J]. Carcinogenesis, 2001, 22 6 1: 957-964. DOI: 10.1093/carcin/22.6.957
[3] HONG LIN. Alterations of Bile Acids and Gut Microbiota in Obesity Induced by High Fat Diet in Rat Model[J]. Journal of Agricultural and Food Chemistry, 2019, 67 13: 3624-3632. DOI: 10.1021/acs.jafc.9b00249
[4] EKKEHARD BAYERDRFFER . Increased serum deoxycholic acid levels in men with colorectal adenomas[J]. Gastroenterology, 1993, 104 1: Pages 145-151. DOI: 10.1016/0016-5085(93)90846-5
DEOXYCHOLIC-2,2,4,4-D4 ACID Preparation Products And Raw materials
Raw materials
Preparation Products
DEOXYCHOLIC-2,2,4,4-D4 ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39043 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Sinco Pharmachem (ShenZhen) R&D Co., Ltd. | +undefined18603013401 | jack.lin@sincopharmachem.com | China | 9999 | 58 |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9679 | 58 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18405 | 56 |
| Artis Biotech Co. Ltd. | 19138486554; 18108108965 | sales@artisbio.com | China | 2158 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71615 | 60 |
| Nanjing Haolv Biotechnology Co.,Ltd | 025-84622273 17361806303 | kexin.zhou@haolvbiotech.com | China | 3019 | 58 |
| Beijing OKA biological technology co., LTD | 010-62971590 18548936886 | 3462612863@qq.com | China | 10063 | 58 |
View Lastest Price from DEOXYCHOLIC-2,2,4,4-D4 ACID manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-04 | Deoxycholic acid-d4
112076-61-6
|
US $342.00-633.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- Deoxycholic acid-d4
112076-61-6
- US $342.00-633.00 / mg
- TargetMol Chemicals Inc.
