4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE
- CAS No.
- 587850-67-7
- Chemical Name:
- 4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE
- Synonyms
- CS-1909;C7280948;AKOS BBB/007;C7280948, >98%;ASISCHEM B51558;C 7280948;C-7280948;4-AMINO-N-PHENETHYL-BENZENESULFONAMIDE;4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE;Benzenesulfonamide, 4-amino-N-(2-phenylethyl)-;4-Amino-N-(2-phenylethyl)benzenesulfonamide C 7280948
- CBNumber:
- CB9493764
- Molecular Formula:
- C14H16N2O2S
- Molecular Weight:
- 276.35
- MDL Number:
- MFCD03716650
- MOL File:
- Mol file
- MSDS File:
- SDS
| Melting point | 143℃ |
|---|---|
| Boiling point | 481.1±55.0 °C(Predicted) |
| Density | 1.258±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | insoluble in H2O; insoluble in EtOH; ≥13.9 mg/mL in DMSO |
| form | solid |
| pka | 12.47±0.50(Predicted) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c | |||||||||
| Hazard Codes | Xi | |||||||||
| HazardClass | IRRITANT | |||||||||
| NFPA 704 |
|
4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 21601 | C-7280948 ≥98% | 587850-67-7 | 100mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 21601 | C-7280948 ≥98% | 587850-67-7 | 250mg | $172 | 2024-03-01 | Buy |
| Cayman Chemical | 21601 | C-7280948 ≥98% | 587850-67-7 | 500mg | $324 | 2024-03-01 | Buy |
| Cayman Chemical | 21601 | C-7280948 ≥98% | 587850-67-7 | 1g | $575 | 2024-03-01 | Buy |
| Biosynth Carbosynth | FA113793 | 4-Amino-N-(2-phenylethyl)benzenesulfonamide | 587850-67-7 | 2g | $434 | 2021-12-16 | Buy |
4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE Chemical Properties,Uses,Production
Biological Activity
c7280948 is a novel prmt1 inhibitor with ic50 value of 12.75 μm [1].protein arginine methyltransferase 1 (prmt1) is a histone methyltransferase specific for histone h4. prmt1 catalyzes the transfer of the methyl group from sam to the guanidine nitrogen atoms of arginine residues to produce monomethyl arginines (mma) and asymmetric dimethyl arginines (adma) [2].c7280948 is a novel prmt1 inhibitor. c7280948 interacts with aromatic residues at the hprmt1 substrate binding pocket (tyr 147 and tyr 160) [1]. c7280948 inhibited hprmt1 with ic50 value of 26.7 μm [3].
References
[1]. heinke r, spannhoff a, meier r, et al. virtual screening and biological characterization of novel histone arginine methyltransferase prmt1 inhibitors. chemmedchem, 2009, 4(1): 69-77.
[2]. itoh y, suzuki t, miyata n. small-molecular modulators of cancer-associated epigenetic mechanisms. mol biosyst, 2013, 9(5): 873-896.
[3]. bissinger em, heinke r, spannhoff a, et al. acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hprmt1. bioorg med chem, 2011, 19(12): 3717-3731.
4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 | |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
View Lastest Price from 4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-09-06 | 4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE
587850-67-7
|
US $1.00 / KG | 1KG | 95%~99% | per week:100kg | Career Henan Chemical Co |
-
- 4-AMINO-N-(2-PHENYLETHYL)BENZENESULFONAMIDE
587850-67-7
- US $1.00 / KG
- 95%~99%
- Career Henan Chemical Co