Minoxidil sulphate
- CAS No.
- 83701-22-8
- Chemical Name:
- Minoxidil sulphate
- Synonyms
- U-58838;MINOXIDIL SULFATE;MINOXIDIL SULPHATE;Minoxidil O-sulfate;minoxidilsulfateester;Sulfuric acid minoxidil;MINOXIDIL SUFATE ETHYLATED;Ketotifen Fumarate Tablets;Minoxidil sulfate (U-58838);Minoxidil sulphate USP/EP/BP
- CBNumber:
- CB9494019
- Molecular Formula:
- C9H15N5O4S
- Molecular Weight:
- 289.31
- MDL Number:
- MFCD06248907
- MOL File:
- 83701-22-8.mol
- MSDS File:
- SDS
Melting point | 175-180°C |
---|---|
Density | 1.75±0.1 g/cm3(Predicted) |
RTECS | UV6260494 |
storage temp. | -20°C |
solubility | Acetone (Slightly), DMSO (Slightly) |
form | White solid. |
pka | -4.99±0.18(Predicted) |
color | White to Off-White |
Stability | Light Sensitive - Protect from Light, Store in Freezer |
InChI | InChI=1S/C9H15N5O4S/c10-7-6-8(13-4-2-1-3-5-13)12-9(11)14(7)18-19(15,16)17/h6,10H,1-5H2,(H2,11,12)(H,15,16,17) |
InChIKey | AGMYAAIWWVATKU-UHFFFAOYSA-N |
SMILES | C1(N)N(OS(O)(=O)=O)C(=N)C=C(N2CCCCC2)N=1 |
CAS DataBase Reference | 83701-22-8(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 2H6K6Y231J |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302-H315-H319-H335-H302-H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338-P301+P312+P330-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xn,T+ | |||||||||
Risk Statements | 22-36/37/38-26/27/28 | |||||||||
Safety Statements | 26-36-45-36/37/39-22 | |||||||||
WGK Germany | 3 | |||||||||
NFPA 704 |
|
Minoxidil sulphate price More Price(19)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | M7920 | Minoxidil sulfate salt | 83701-22-8 | 1mg | $42.9 | 2024-03-01 | Buy |
Sigma-Aldrich | M7920 | Minoxidil sulfate salt | 83701-22-8 | 5mg | $195 | 2024-03-01 | Buy |
Alfa Aesar | J67021 | Minoxidil sulfate, 98% | 83701-22-8 | 5mg | $128 | 2021-12-16 | Buy |
TRC | M345100 | MinoxidilSulfate | 83701-22-8 | 25mg | $145 | 2021-12-16 | Buy |
TRC | M345100 | MinoxidilSulfate | 83701-22-8 | 50mg | $275 | 2021-12-16 | Buy |
Minoxidil sulphate Chemical Properties,Uses,Production
Application
Chemical Properties
White Crystalline Solid
Uses
Minoxidil sulfate (MXS) has been used as a drug agent to study its effects on alopecia in corticotropin-releasing factor over-expressing (CRF-OE) mice. It has also been used as a positive control in an assay for the culturing of rat vibrissa follicles.
Uses
specifically opens ATP-sensitive K channels, strong vascular smooth muscle relaxer, active minoxidil metabolite
Uses
A selective ATP-sensitive potassium channel opener. It is the active metabolite of minoxidil and is a potent (IC50=0.14) vascular smooth muscle relaxant
Biological Functions
Minoxidil sulfate is the active metabolite of Minoxidil and is a potent (IC50=0.14M) vascular smooth muscle relaxant. Minoxidil sulfate is a selective ATP-sensitive potassium channel opener.
Biochem/physiol Actions
Minoxidil sulfate (MXS) is an endogenous derivative of minoxidil. It possesses greater aqueous solubility and is a potent vasodilator. MXS has the potential to treat androgenic alopecia or male baldness.
in vitro
Minoxidil sulfate (1-100 μM; 2 hours) significantly reduces the permeability of bloode-brain tumor barrier (BTB) in a monolayer of RBMEC in a time-dependent manner, additionally,the effects of MS on transendothelial electrical resistance (TEER) is Transendothelial electrical resistance (TEER) at 2 h with high concentration.Minoxidil sulfate (0-100 μM; 0-4 hours) increases the RhoA activation in brain tumor tissue by 1 h and the highest level appears at 2 h, it also significantly induces transient PKB phosphorylation at Ser-473, without affecting total PKB levels. Addiotionally, LY294002 partly prevents the phosphorylation of PKB induced by MS.
Minoxidil sulphate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Wuhan Golt Biotech Co., Ltd. | +8615389281203 | maria@goltbiotech.com | China | 980 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
Hong Kong Excellence Biotechnology Co., Ltd. | +86-86-18838029171 +8618126314766 | ada@sh-teruiop.com | China | 893 | 58 |
Anhui Yiao New Material Technology Co., Ltd | +86-199-55145978 +8619955145978 | sales8@anhuiyiao.com | China | 253 | 58 |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
Sigma Audley | +86-18336680971 +86-18126314766 | nova@sh-teruiop.com | China | 525 | 58 |
airuikechemical co., ltd. | +undefined86-15315557071 | sales02@airuikechemical.com | China | 994 | 58 |
Shanghai Aosiris new Material Technology Co., LTD | 86-15139564871 +8615139564871 | wrjmoon2000@163.com | China | 354 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
Related articles
- Minoxidil sulphate: History and Pharmacokinetics
- Minoxidil sulphate, approved for hypertension, later found use in treating baldness due to hypertrichosis. Its absorption and ....
- Mar 28,2024
- Minoxidil sulphate: origin, mechanism of action and applications
- Minoxidil sulphate is a commonly used treatment for hair loss, promoting hair regrowth and reducing hair loss.
- Oct 17,2023
- What is Minoxidil sulphate?
- Minoxidil sulfate was the drug approved by the FDA for the treatment of androgenetic alopecia (hair loss).Before that, minoxid....
- Feb 17,2020
View Lastest Price from Minoxidil sulphate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-04-23 | Minoxidil Sulfate
83701-22-8
|
US $100.00 / kg | 1kg | >99% | 20tons | Hong Kong Excellence Biotechnology Co., Ltd. | ||
2024-04-12 | Minoxidil sulphate
83701-22-8
|
US $0.00-0.00 / KG | 1KG | 99% | 10000 Mt/Year | Shaanxi Haibo Biotechnology Co., Ltd | ||
2024-04-12 | Minoxidil sulphate
83701-22-8
|
US $3.00-1.00 / kg | 1kg | 99.9% | 10 tons | Shanghai Aosiris new Material Technology Co., LTD |
- Minoxidil Sulfate
83701-22-8
- US $100.00 / kg
- >99%
- Hong Kong Excellence Biotechnology Co., Ltd.
- Minoxidil sulphate
83701-22-8
- US $0.00-0.00 / KG
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
- Minoxidil sulphate
83701-22-8
- US $3.00-1.00 / kg
- 99.9%
- Shanghai Aosiris new Material Technology Co., LTD
83701-22-8(Minoxidil sulphate)Related Search:
1of4