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AMITRIPTYLINE METABOLITE (+/-)-

AMITRIPTYLINE METABOLITE (+/-)- structure

CAS No.: 64520-05-4

Chemical Name:: AMITRIPTYLINE METABOLITE (+/-)-

Synonyms: 10-Hydroxy (E)-Amitriptyline;AMITRIPTYLINE METABOLITE (+/-)-;AMITRIPTYLINE METABOLITE (+-)-(E)-10-HYD ROXYLA;Amitriptyline metabolite, (±)-E-10-hydroxylated-;(E)-5-(3-(Dimethylamino)propylidene)-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol;5H-Dibenzo[a,d]cyclohepten-10-ol, 5-[3-(dimethylamino)propylidene]-10,11-dihydro-, (5E)-;(11E)-11-[3-(dimethylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol

CBNumber:: CB9496952

Molecular Formula:: C20H23NO

Molecular Weight:: 293.4

MDL Number:: MFCD00069200

MOL File:: 64520-05-4.mol

MSDS File:: SDS

Last updated:2023-05-04 17:34:41

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AMITRIPTYLINE METABOLITE (+/-)- Properties

Melting point	97-99 °C
Boiling point	453.3±45.0 °C(Predicted)
Density	1.151±0.06 g/cm3(Predicted)
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	0.1 M HCl: soluble
pka	13.89±0.20(Predicted)
form	solid
color	white
Stability	Hygroscopic
FDA UNII	8646K54I21
EPA Substance Registry System	5H-Dibenzo[a,d]cyclohepten-10-ol, 5-[3-(dimethylamino)propylidene]-10,11-dihydro-, (5E)- (64520-05-4)

SAFETY

Risk and Safety Statements

Safety Statements	22-24/25
WGK Germany	3

AMITRIPTYLINE METABOLITE (+/-)- price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	A115	Amitriptyline metabolite, (±)-E-10-hydroxylated- analytical standard	64520-05-4	2mg	$310	2024-03-01	Buy
TRC	D462790	10-Hydroxy(E)-Amitriptyline	64520-05-4	10mg	$1605	2021-12-16	Buy
TRC	D462790	10-Hydroxy(E)-Amitriptyline	64520-05-4	25mg	$3550	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0163570	(+/-)-E-5-[3-(DIMETHYLAMINO)PROPYLIDENE]-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-10-OL 95.00%	64520-05-4	5MG	$502.87	2021-12-16	Buy

Product number	Packaging	Price	Buy
A115	2mg	$310	Buy
D462790	10mg	$1605	Buy
D462790	25mg	$3550	Buy
CHM0163570	5MG	$502.87	Buy

AMITRIPTYLINE METABOLITE (+/-)- Chemical Properties,Uses,Production

Uses

(5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).

Definition

ChEBI: E-10-Hydroxyamitriptyline is an organic tricyclic compound.

Biochem/physiol Actions

Metabolite of amitriptyline, tricyclic antidepressant; chromatographic standard.

AMITRIPTYLINE METABOLITE (+/-)- Preparation Products And Raw materials

Raw materials

Preparation Products

AMITRIPTYLINE METABOLITE (+/-)- Suppliers

Global( 7)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai ring qi biological technology co., LTD	13524106587	sales@hq-chem.com	China	225	58

Supplier	Advantage
Sigma-Aldrich	80
Shanghai ring qi biological technology co., LTD	58

64520-05-4(AMITRIPTYLINE METABOLITE (+/-)-)Related Search:

AMITRIPTYLINE METABOLITE (+/-)- Amitriptyline cyproheptadine 10,11-epoxide 10,11-DIHYDRO-5 H-DIBENZO[A,D]CYCLOHEPTENE 1,1-DI(O-TOLYL)ETHYLENE

NORTRIPTYLINE

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AMITRIPTYLINE METABOLITE (+/-)- AMITRIPTYLINE METABOLITE (+-)-(E)-10-HYD ROXYLA (11E)-11-[3-(dimethylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol 5H-Dibenzo[a,d]cyclohepten-10-ol, 5-[3-(dimethylamino)propylidene]-10,11-dihydro-, (5E)- 10-Hydroxy (E)-Amitriptyline Amitriptyline metabolite, (±)-E-10-hydroxylated- (E)-5-(3-(Dimethylamino)propylidene)-10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-ol 64520-05-4